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1.
JAMA ; 277(11): 904-8, 1997 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-9062329

RESUMO

OBJECTIVE: To describe a coccidioidomycosis outbreak in Ventura County following the January 1994 earthquake, centered in Northridge, Calif, and to identify factors that increased the risk for acquiring acute coccidioidomycosis infection. DESIGN: Epidemic investigation, population-based skin test survey, and case-control study. SETTING: Ventura County, California. RESULTS: In Ventura County, between January 24 and March 15, 1994, 203 outbreak-associated coccidioidomycosis cases, including 3 fatalities, were identified (attack rate [AR], 30 cases per 100,000 population). The majority of cases (56%) and the highest AR (114 per 100,000 population) occurred in the town of Simi Valley, a community located at the base of a mountain range that experienced numerous landslides associated with the earthquake. Disease onset for cases peaked 2 weeks after the earthquake. The AR was 2.8 times greater for persons 40 years of age and older than for younger persons (relative risk, 2.8; 95% confidence interval [CI], 2.1-3.7; P<.001). Environmental data indicated that large dust clouds, generated by landslides following the earthquake and strong aftershocks in the Santa Susana Mountains north of Simi Valley, were dispersed into nearby valleys by northeast winds. Simi Valley case-control study data indicated that physically being in a dust cloud (odds ratio, 3.0; 95% CI, 1.6-5.4; P<.001) and time spent in a dust cloud (P<.001) significantly increased the risk for being diagnosed with acute coccidioidomycosis. CONCLUSIONS: Both the location and timing of cases strongly suggest that the coccidioidomycosis outbreak in Ventura County was caused when arthrospores were spread in dust clouds generated by the earthquake. This is the first report of a coccidioidomycosis outbreak following an earthquake. Public and physician awareness, especially in endemic areas following similar dust cloud-generating events, may result in prevention and early recognition of acute coccidioidomycosis.


Assuntos
Coccidioidomicose/epidemiologia , Desastres , Surtos de Doenças , Doença Aguda , Adolescente , Adulto , Idoso , Análise de Variância , California/epidemiologia , Estudos de Casos e Controles , Criança , Pré-Escolar , Coccidioides/isolamento & purificação , Coccidioidomicose/diagnóstico , Exposição Ambiental , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Vigilância da População , Fatores de Risco , Testes Sorológicos , Testes Cutâneos
2.
Science ; 238(4829): 921-5, 1987 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-17829356

RESUMO

A real-time system for issuing warnings of landslides during major storms is being developed for the San Francisco Bay region, California. The system is based on empirical and theoretical relations between rainfall and landslide initiation, geologic determination of areas susceptible to landslides, real-time monitoring of a regional network of telemetering rain gages, and National Weather Service precipitation forecasts. This system was used to issue warnings during the storms of 12 to 21 February 1986, which produced 800 millimeters of rainfall in the region. Although analysis after the storms suggests that modifications and additional development are needed, the system successfully predicted the times of major landslide events. It could be used as a prototype for systems in other landslide-prone regions.

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