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1.
Am J Trop Med Hyg ; 43(4): 410-8, 1990 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-2240369

RESUMO

Preliminary studies found that 9% of Guaymi Indians from Bocas del Toro province have antibody to human T cell lymphotropic virus (HTLV-I/II). The present study enrolled 317 (21% of the population) Guaymi Indians from Changuinola, the capital of Bocas del Toro province and 333 (70% of the population) from Canquintu, an isolated rural village. Demographic information and family relationships were ascertained and subjects were screened for neurologic diseases. Serum specimens were screened by an enzyme-linked immunosorbent assay for HTLV-I/II antibody and positives were confirmed according to U.S. Public Health Service criteria. Twenty-five (8%) Guaymi residing in Changuinola and 7 (2.1%) from Canquintu were confirmed seropositive. In Changuinola, antibody was virtually limited to residents greater than or equal to 15 years of age (24 [16%] of 153) and rates were slightly higher in males than in females; in Canquintu, antibody rates did not increase significantly with age and appeared higher in females than in males. In Changuinola, there was no evidence for household clustering of infection. In contrast, HTLV antibody among Canquintu residents clustered significantly by household. HTLV-associated neurologic disease was not detected in either population. The atypical seroepidemiology observed in both locations might be explained if the virus endemic to the Guaymi differed from HTLV-I previously described in the Caribbean basin and Japan.


Assuntos
Infecções por HTLV-I/epidemiologia , Infecções por HTLV-II/epidemiologia , Indígenas Centro-Americanos , Adolescente , Adulto , Fatores Etários , Western Blotting , Criança , Ensaio de Imunoadsorção Enzimática , Feminino , Anticorpos Anti-HTLV-I/análise , Infecções por HTLV-I/complicações , Anticorpos Anti-HTLV-II/análise , Infecções por HTLV-II/complicações , Hepatite B/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Panamá/epidemiologia , Prevalência , Fatores Sexuais
3.
Am J Trop Med Hyg ; 40(6): 659-62, 1989 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-2742042

RESUMO

Serum specimens from Puerto Rican residents were tested for antibodies to human T lymphotropic virus type I (HTLV-I) using an enzyme immunoassay, Western immunoblot, and radioimmunoprecipitation assays. Of 1,279 specimens obtained during a dengue virus surveillance program in 1986 and 1987, 3 (0.2%) tested positive; an additional 11 were indeterminate. Of 602 specimens obtained from blood donors in Ponce in 1987, 1 (0.2%) was positive; an additional specimen was indeterminate. Of 21 persons hospitalized for problems related to intravenous drug use in 1986 and 1987, 1 (5%) tested positive for HTLV-I antibodies.


Assuntos
Anticorpos Anti-HTLV-I/análise , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Western Blotting , Criança , Pré-Escolar , Ensaio de Imunoadsorção Enzimática , Feminino , Genes Virais , Anticorpos Anti-HTLV-I/genética , Infecções por HTLV-I/epidemiologia , Infecções por HTLV-I/imunologia , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Porto Rico
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