RESUMO
To determine the best combination of parameters that would improve the diagnostic performance of exercise testing, coronary angiography plus exercise testing were done on 112 patients with angina pectoris and normal electrocardiogram. The univariate predictors of coronary artery disease included: age > or = 40 years, male sex, hypertension, smoking, development of exertional chest pain, decrease in systolic blood pressure (BP) > or = 10 mmHg or systolic BP 3 min post-exercise > 90% of peak, heart rate drop < 12 beats/min 1 min postexercise, exercise-induced ST-segment depression > or = 1 mm. Multivariate logistic regression analysis showed that using either ST depression > or = 1 mm or peak exercise QTDc > 70 ms significantly improved sensitivity and negative predictive value of the test without a significant decrease in specificity.
Assuntos
Angiografia Coronária/métodos , Doença da Artéria Coronariana/diagnóstico , Interpretação Estatística de Dados , Eletrocardiografia/métodos , Teste de Esforço/métodos , Distribuição por Idade , Análise de Variância , Angina Pectoris/etiologia , Doença da Artéria Coronariana/epidemiologia , Doença da Artéria Coronariana/etiologia , Egito/epidemiologia , Feminino , Humanos , Hipertensão/complicações , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Sensibilidade e Especificidade , Distribuição por Sexo , Fumar/efeitos adversos , Estatísticas não ParamétricasRESUMO
To determine the best combination of parameters that would improve the diagnostic performance of exercise testing, coronary angiography plus exercise testing were done on 112 patients with angina pectoris and normal electrocardiogram. The univariate predictors of coronary artery disease included: age >/= 40 years, male sex, hypertension, smoking, development of exertional chest pain, decrease in systolic blood pressure [BP] >/= 10 mmHg or systolic BP 3 min post-exercise > 90% of peak, heart rate drop < 12 beats/min 1 min post-exercise, exercise-induced ST-segment depression >/= 1mm. Multivariate logistic regression analysis showed that using either ST depression >/= 1mm or peak exercise QTDc > 70 ms significantly improved sensitivity and negative predictive value of the test without a significant decrease in specificity
