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1.
PLoS One ; 19(4): e0302358, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38640105

RESUMO

This study aims to develop an optimally performing convolutional neural network to classify Alzheimer's disease into mild cognitive impairment, normal controls, or Alzheimer's disease classes using a magnetic resonance imaging dataset. To achieve this, we focused the study on addressing the challenge of image noise, which impacts the performance of deep learning models. The study introduced a scheme for enhancing images to improve the quality of the datasets. Specifically, an image enhancement algorithm based on histogram equalization and bilateral filtering techniques was deployed to reduce noise and enhance the quality of the images. Subsequently, a convolutional neural network model comprising four convolutional layers and two hidden layers was devised for classifying Alzheimer's disease into three (3) distinct categories, namely mild cognitive impairment, Alzheimer's disease, and normal controls. The model was trained and evaluated using a 10-fold cross-validation sampling approach with a learning rate of 0.001 and 200 training epochs at each instance. The proposed model yielded notable results, such as an accuracy of 93.45% and an area under the curve value of 0.99 when trained on the three classes. The model further showed superior results on binary classification compared with existing methods. The model recorded 94.39%, 94.92%, and 95.62% accuracies for Alzheimer's disease versus normal controls, Alzheimer's disease versus mild cognitive impairment, and mild cognitive impairment versus normal controls classes, respectively.


Assuntos
Doença de Alzheimer , Disfunção Cognitiva , Humanos , Doença de Alzheimer/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Redes Neurais de Computação , Algoritmos , Aumento da Imagem , Disfunção Cognitiva/diagnóstico por imagem , Neuroimagem/métodos
2.
Comput Intell Neurosci ; 2022: 1189509, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36203732

RESUMO

Computer vision is the science that enables computers and machines to see and perceive image content on a semantic level. It combines concepts, techniques, and ideas from various fields such as digital image processing, pattern matching, artificial intelligence, and computer graphics. A computer vision system is designed to model the human visual system on a functional basis as closely as possible. Deep learning and Convolutional Neural Networks (CNNs) in particular which are biologically inspired have significantly contributed to computer vision studies. This research develops a computer vision system that uses CNNs and handcrafted filters from Log-Gabor filters to identify medicinal plants based on their leaf textural features in an ensemble manner. The system was tested on a dataset developed from the Centre of Plant Medicine Research, Ghana (MyDataset) consisting of forty-nine (49) plant species. Using the concept of transfer learning, ten pretrained networks including Alexnet, GoogLeNet, DenseNet201, Inceptionv3, Mobilenetv2, Restnet18, Resnet50, Resnet101, vgg16, and vgg19 were used as feature extractors. The DenseNet201 architecture resulted with the best outcome of 87% accuracy and GoogLeNet with 79% preforming the worse averaged across six supervised learning algorithms. The proposed model (OTAMNet), created by fusing a Log-Gabor layer into the transition layers of the DenseNet201 architecture achieved 98% accuracy when tested on MyDataset. OTAMNet was tested on other benchmark datasets; Flavia, Swedish Leaf, MD2020, and the Folio dataset. The Flavia dataset achieved 99%, Swedish Leaf 100%, MD2020 99%, and the Folio dataset 97%. A false-positive rate of less than 0.1% was achieved in all cases.


Assuntos
Aprendizado Profundo , Plantas Medicinais , Algoritmos , Inteligência Artificial , Humanos , Redes Neurais de Computação
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