Diagnosis of visceral form of Isospora infection (atoxoplasma) in black spot syndrome in canaries, in Iran.

The gastrointestinal form of Isospora is well described in Passeriformes, but there are few reports of the visceral form of Isospora. Therefore, to evaluate the visceral form of Isospora in canaries with "black spot" syndrome, gastrointestinal contents were prepared from 50 canaries that were lost and appeared with black spot under the skin of the abdomen. At the same time, tissue samples were collected from visceral tissues. After preparing the samples, the oocysts were counted in the digestive contents. A total of 7 canaries out of 50 canaries showed oocysts in their feces. Following the identification of infected birds, histopathological sections were prepared from their visceral tissues. Visceral tissues included the heart, liver, and intestine. Inflammation and hyperemia were seen in the microscopic view of the heart, but no developing stage of parasites was seen. The liver showed inflammation as well as the asexual reproductive stage of the parasite. The asexual reproductive stage of the parasite was also observed in the intestine. Therefore, Isospora seems to be involved in the syndrome of black spot in canaries by causing gastrointestinal and visceral lesions.

Acute Bilateral Neuroretinitis and Panuveitis in A Patient with Coronavirus Disease 2019: A Case Report.

Purpose: Herein, we report a case of bilateral neuroretinitis and panuveitis in a patient recovered from coronavirus disease 2019 (COVID-19).Case presentation: A 37-year-old male patient with a history of recovered COVID-19, which was confirmed with nasopharyngeal reverse transcriptase polymerase chain reaction (RT-PCR) for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), about one-month ago was referred with one-week history of bilateral severe vision loss. Visual acuity was counting fingers, and bilateral retinitis and panuveitis were revealed in ocular examination. The result of the vitreous sample using RT-PCR was positive for SARS-CoV-2 and negative for Herpesviridae viruses and mycobacterium tuberculosis. The patient was successfully treated with corticosteroid.Conclusion: We report a case of bilateral neuroretinitis and panuveitisin a recovered COVID-19 patient and positive RT-PCR of the vitreous sample. It is suggested to apply intraocular sampling and evaluation for COVID-19 in patients with the new-onset of uveitis and/or retinitis during the pandemic.