[25 Years of TraumaTherapy with Children and Adolescents ‒ a Personal-Professional Review]. / 25 Jahre Traumatherapie mit Kindern und Jugendlichen ­ ein persönlich-fachlicher Rückblick.

The author was fortunate to experience and help shape the development of the trauma approach with children and adolescents from the very beginning. This brought a great joy for and in the therapeutic work, an intense impulse for one's own inner work, an intellectual pleasure in working out new concepts andmany wonderful encounters in all the workshops with people who had the welfare of children so much at heart. He is deeply convinced that the future belongs to this approach because it is effective and counteracts the "privatization of stress" (Fisher, 2013).

[Resource-Oriented Narrative TraumaTherapy (Resonat): Treating Complex Trauma Disorders in Children and Adolescents Gently and Specifically]. / Ressourcenorientierte narrative Traumatherapie (ResonaT): Komplexe Traumafolgestörungen bei Kindern und Jugendlichen schonend und spezifisch behandeln.

Resource-oriented narrative trauma therapy (ResonaT; Hiller u. Hensel, 2019) is an innovative and creative approach within existing narrative trauma procedures. It is based on the three core elements of modern trauma therapy (actualisation, resource activation, dual attention) and invokes the neurobiological self-healing mechanism of memory reconsolidation. Due to its low demands on the children, its resourceful and gentle actualisation of the traumatic material, the distance-creating use of animal protagonists and a supportive therapeutic relationship, it is particularly suitable for children and adolescents with complex trauma sequelae. Through specific structuring (orientation to the leading symptoms, elaboration of central basic emotions, allocation of current triggers to earlier traumatic events), the narratives can be formulated precisely for each child.The workload for the therapists is made considerably easier by the availability of around 100 elaborated, topic-specific narratives.

Synthesis and properties of unsymmetrical azatrioxa[8]circulenes.

Insights to the subtle reactivity patterns of hydroxy-substituted carbazoles allows the precise synthesis of unsymmetrical azatrioxa[8]circulenes by the reaction of N-benzyl-2,7-di-tert-butyl-3,6-dihydroxycarbazole with two different 1,4-benzoquinones in the presence of an oxidant (chloranil) and a Lewis acid (BF3OEt2). The unique synthetic control obtained originates from the selectivity obtained upon reacting N-benzyl-2,7-di-tert-butyl-3,6-dihydroxycarbazole with an electron-rich benzoquinone to give first the C-C bond formation and then subsequently the dibenzofuran formation with high regioselectivity. Herein the first synthesis of unsymmetrical antiaromatic azatrioxa[8]circulenes and the full characterization using NMR spectroscopy, optical spectroscopy, electrochemistry, computational techniques and single crystal X-ray crystallography is reported. The controlled stepwise condensation of N-benzyl-2,7-di-tert-butyl-3,6-dihydroxycarbazole with two different 1,4-benzoquinones gives selectively the unsymmetrical azatrioxa[8]circulenes.

Diazadioxa[8]circulenes: planar antiaromatic cyclooctatetraenes.

In this paper we describe a new class of antiaromatic planar cyclooctatetraenes: the diazadioxa[8]circulenes. The synthesis was achieved by means of a new acid-mediated oxidative dimerization of 3,6-dihydroxycarbazoles to yield the diazadioxa[8]circulenes in high yields. The synthetic protocol appears to be general, and is a one-pot transformation in which two C-C bonds and two C-O bonds are formed with the loss of two molecules of water. We also present a detailed characterization of the optical and electrochemical properties of this new class of stable planar cyclooctatetraenes. The properties of the diazadioxa[8]circulenes are compared with the properties of isoelectronic tetraoxa[8]circulenes and azatrioxa[8]circulenes. We discuss the antiaromatic nature of the planar central cyclooctatetraene moiety. The antiaromatic nature of the planar cyclooctatetraenes was studied by using computational methods (NICS calculations), and these calculations reveal that the central eight-membered ring has antiaromatic character.

Azatrioxa[8]circulenes: planar anti-aromatic cyclooctatetraenes.

We describe herein the first synthesis of a new class of anti-aromatic planar cyclooctatetraenes: the azatrioxa[8]circulenes. This was achieved by treating a suitably functionalised 3,6-dihydroxycarbazole with 1,4-benzoquinones or a 1,4-naphthoquinone. We fully characterised the azatrioxa[8]circulenes by using optical, electrochemical and computational techniques as well as by single-crystal X-ray crystallography. The results of a computational study (NICS) suggest that the central planar cyclooctatetraene is anti-aromatic when the molecules are in neutral or oxidised states (2+), and that the corresponding dianions are aromatic. We discuss the aromatic/anti-aromatic nature of the planar cyclooctatetraenes and compare them with the isoelectronic tetraoxa[8]circulenes.

EEG parameters and their combination as indicators of depth of anaesthesia.

EEG parameters for assessment of depth of anaesthesia are typically based on different signal processing methods, such as spectral and complexity analysis. In the present study, the parameters investigated (WSMF, qWSMF, approximate entropy and Lempel-Ziv complexity) do not correlate monotonically to depth of anaesthesia. To obtain this correlation, parameters are combined based on fuzzy inference, whereby each parameter only operates in a specific range. Fuzzy inference seems to be a suitable approach, as the indicator designed separates wakefulness from unconsciousness as well as the best single parameter does and correlates to the depth of anaesthesia.