Home exercise, branched-chain amino acids, and probiotics improve frailty in cirrhosis: A randomized clinical trial.

BACKGROUND: Frailty is a predictive factor of hospitalization, falls, and mortality in patients with cirrhosis, regardless of the degree of liver failure. The aim was to analyze whether a multifactorial intervention consisting of home-based exercise, branched-chain amino acids, and a multistrain probiotic can improve frailty in these patients. METHODS: Outpatients with cirrhosis were classified according to the Liver Frailty Index (LFI). Prefrail and frail patients were randomized into 2 groups. The intervention group was assigned to a multifactorial intervention consisting of exercise at home, branched-chain amino acid supplements, and a multistrain probiotic for 12 months. The control group received standard care. All patients were prospectively followed up every 3 months for 1 year to determine LFI, incidence of falls, emergency room visits, hospitalizations, and mortality. RESULTS: Thirty-two patients were included: 17 patients were assigned to the intervention group and 15 to the control group. In the intervention group, the baseline LFI decreased at 3, 6, 9, and 12 months (p = 0.019 for overall change with respect to the control group). The change in LFI (ΔLFI) at 12 months was -0.71 ± 0.24 in the intervention group and -0.09 ± 0.32 in the control group (p<0.001). During follow-up, patients in the intervention group had a lower 1-year probability of falls (6% vs. 47%, p = 0.03) and emergency room visits (10% vs. 44%, p = 0.04) than patients in the control group. CONCLUSIONS: A long-term multifactorial intervention that included exercise at home, branched-chain amino acids, and a multistrain probiotic improved frailty in outpatients with cirrhosis and was associated with a decrease in the incidence of clinical events such as falls and emergency room visits.

Libro "Fractura de cadera en el adulto mayor": recurso de aprendizaje para el médico general / Book "Hip fracture in the elderly": learning resource for the general practitioner

Fundamento: los medios de enseñanza constituyen uno de los ejes vertebrales de las acciones en cualquiera de los niveles de la educación. Objetivo: mostrar los fundamentos teóricos del libro: "Fractura de cadera en el adulto mayor", como recurso de aprendizaje para la superación profesional del médico de familia. Métodos: se realizó una investigación con enfoque cualitativo en la Universidad de Ciencias Médicas "Dr. Zoilo Marinello Vidaurreta" de Las Tunas en el año 2021. Se emplearon métodos del nivel teórico para la fundamentación teórica; y empírico: análisis documental para verificar los nexos y relaciones que se ofrecen en los referentes teóricos relacionados con las características que debe poseer un libro de texto como medio de enseñanza en el proceso docente educativo, su importancia, ventajas y fundamentos. Se utilizó el criterio de expertos para valorar su pertinencia, factibilidad y estructura metodológica. Resultados: se presenta un libro diseñado como recurso del aprendizaje para la superación profesional, contiene las particularidades del contenido que se desea enseñar y lo que necesitan aprender los médicos de familia sobre la atención al adulto mayor con fractura de cadera. Está estructurado en trece capítulos con predominio de interrogantes que son respondidas con precisión y claridad. Se resaltan los fundamentos teóricos que lo sustentan. Conclusiones: se mostraron los principales fundamentos teóricos del libro "Fractura de cadera en el adulto mayor", como medio de enseñanza para la superación profesional del médico de familia y se resaltaron sus principales ventajas como componente didáctico del proceso docente educativo.

Background: the teaching means constitute one of the backbones of the actions at any level of education. Objective: to show the theoretical foundations of the book: "Hip fracture in the elderly", as a learning resource for the professional improvement of the family doctor. Methods: a research with a qualitative approach was carried out at "Dr. Zoilo Marinello Vidaurreta" University of Medical Sciences from Las Tunas in 2021. Theoretical methods were used for the theoretical foundation; and documentary analysis as an empirical one to verify the links and relationships that are offered in the theoretical references related to the characteristics that a textbook must have as a teaching medium in the educational process, its importance, advantages and foundations. Expert criteria were used to assess its relevance, feasibility and methodological structure. Results: a book designed as a learning resource for professional improvement is presented; it contains the particularities of the content to be taught and what family doctors need to learn about care for the elderly with hip fracture. It is structured in thirteen chapters with a predominance of questions which are answered with precision and clarity. Its theoretical foundations are highlighted. Conclusions: the main theoretical foundations of the book "Hip fracture in the elderly" were shown as a teaching tool for the professional improvement of the family doctor and its main advantages as a didactic component of the educational teaching process were highlighted.

The yeast two-component SLN1 branch of the HOG pathway and the scaffolding activity of Pbs2 modulate the response to endoplasmic reticulum stress induced by tunicamycin / La rama SLN1 de dos componentes de levadura de la vía HOG y la actividad de andamiaje de Pbs2 modulan la respuesta al estrés del retículo endoplásmico inducido por tunicamicina

In addition to the UPR pathway, yeast cells require components of the HOG pathway to respond to ER stress. In this work, we found that unphosphorylated Sln1 and Ssk1 are required to mount an appropriate response to Tn. We also found that the MAPKKKs Ssk2 participates in the Tn response, but its osmo-redundant protein Ssk22 does not. We also found that the Pbs2 docking sites for Ssk2 (RDS-I and KD) are partially dispensable when mutated separately; however, the prevention of Ssk2 binding to Pbs2, by the simultaneous mutation of RDS-I and KD, caused strong sensitivity to Tn. In agreement with the lack of Hog1 phosphorylation during Tn treatment, a moderate resistance to Tn is obtained when a Pbs2 version lacking its kinase activity is expressed; however, the presence of mutual Pbs2-Hog1 docking sites is essential for the Tn response. Finally, we detected that Tn induced a transcriptional activation of some components of the SLN1 branch. These results indicate that the Tn response requires a complex formed by the MAPK module and components of the SLN1 branch but not their canonical osmoregulatory activities.(AU)

Post-transcriptional regulation during stress.

To remain competitive, cells exposed to stress of varying duration, rapidity of onset, and intensity, have to balance their expenditure on growth and proliferation versus stress protection. To a large degree dependent on the time scale of stress exposure, the different levels of gene expression control: transcriptional, post-transcriptional, and post-translational, will be engaged in stress responses. The post-transcriptional level is appropriate for minute-scale responses to transient stress, and for recovery upon return to normal conditions. The turnover rate, translational activity, covalent modifications, and subcellular localisation of RNA species are regulated under stress by multiple cellular pathways. The interplay between these pathways is required to achieve the appropriate signalling intensity and prevent undue triggering of stress-activated pathways at low stress levels, avoid overshoot, and down-regulate the response in a timely fashion. As much of our understanding of post-transcriptional regulation has been gained in yeast, this review is written with a yeast bias, but attempts to generalise to other eukaryotes. It summarises aspects of how post-transcriptional events in eukaryotes mitigate short-term environmental stresses, and how different pathways interact to optimise the stress response under shifting external conditions.

The yeast two-component SLN1 branch of the HOG pathway and the scaffolding activity of Pbs2 modulate the response to endoplasmic reticulum stress induced by tunicamycin.

In addition to the UPR pathway, yeast cells require components of the HOG pathway to respond to ER stress. In this work, we found that unphosphorylated Sln1 and Ssk1 are required to mount an appropriate response to Tn. We also found that the MAPKKKs Ssk2 participates in the Tn response, but its osmo-redundant protein Ssk22 does not. We also found that the Pbs2 docking sites for Ssk2 (RDS-I and KD) are partially dispensable when mutated separately; however, the prevention of Ssk2 binding to Pbs2, by the simultaneous mutation of RDS-I and KD, caused strong sensitivity to Tn. In agreement with the lack of Hog1 phosphorylation during Tn treatment, a moderate resistance to Tn is obtained when a Pbs2 version lacking its kinase activity is expressed; however, the presence of mutual Pbs2-Hog1 docking sites is essential for the Tn response. Finally, we detected that Tn induced a transcriptional activation of some components of the SLN1 branch. These results indicate that the Tn response requires a complex formed by the MAPK module and components of the SLN1 branch but not their canonical osmoregulatory activities.

Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis.

The phase angle is a versatile measurement to assess body composition, frailty and prognosis in patients with chronic diseases. In cirrhosis, patients often present alterations in body composition that are related to adverse outcomes. The phase angle could be useful to evaluate prognosis in these patients, but data are scarce. The aim was to analyse the prognostic value of the phase angle to predict clinically relevant events such as hospitalisation, falls, and mortality in patients with cirrhosis. Outpatients with cirrhosis were consecutively included and the phase angle was determined by electrical bioimpedance. Patients were prospectively followed to determine the incidence of hospitalisations, falls, and mortality. One hundred patients were included. Patients with phase angle ≤ 4.6° (n = 31) showed a higher probability of hospitalisation (35% vs 11%, p = 0.003), falls (41% vs 11%, p = 0.001) and mortality (26% vs 3%, p = 0.001) at 2-year follow-up than patients with PA > 4.6° (n = 69). In the multivariable analysis, the phase angle and MELD-Na were independent predictive factors of hospitalisation and mortality. Phase angle was the only predictive factor for falls. In conclusion, the phase angle showed to be a predictive marker for hospitalisation, falls, and mortality in outpatients with cirrhosis.

Frailty in outpatients with cirrhosis: A prospective observational study.

BACKGROUND AND AIM: Frailty is increasingly recognized as a major prognostic factor in cirrhosis in addition to conventional liver insufficiency scores. The aim was to compare the prevalence and characteristics of frailty between patients with cirrhosis and controls, and to analyse its prognostic value. METHODS: We included outpatients with cirrhosis and age- and gender-matched non-cirrhotic controls. Frailty was defined according to the Fried frailty criteria. In patients with cirrhosis, we analysed the ability of the degree of frailty to predict a composite endpoint, consisting of hospitalization, admission to a long-term care centre, falls or death. RESULTS: We included 135 patients with cirrhosis and 135 controls. The prevalence of frailty was higher among patients with cirrhosis: 35 (25.9%) frail, 74 (54.8%) pre-frail and 26 (19.2%) robust vs 14 (10.4%) frail, 67 (49.6%) pre-frail and 54 (40%) robust (P < .001) in controls. This difference was mainly as a result of decreased muscle strength in patients with cirrhosis. During follow-up, frail patients with cirrhosis showed a higher probability of composite endpoint, hospitalization and falls than pre-frail and robust cirrhotic patients but mortality was similar. MELD-Na score and frailty were independent predictive factors for hospitalization, frailty for falls, and MELD-Na score and albumin for survival. Vitamin D deficiency and increased cystatin C were associated with frailty. CONCLUSIONS: Frailty was more frequent in outpatients with cirrhosis than in controls, mainly because of a decrease in muscle strength, and it could be a predictive factor for hospitalization and falls in these patients.

Utilidad de los marcadores bioquímicos de preeclampsia / Usefulness of the biochemical markers of pre-eclampsia

La preeclampsia (PE) constituye una de las principales causas de mortalidad materna y perinatal en el mundo. En los países desarrollados, los estudios apuntan a un importante aumento de la incidencia de PE en la última década, en parte, por el aumento de la prevalencia, en la población general, de enfermedades que afectan a la función vascular, como la diabetes, la hipertensión crónica o la enfermedad renal. En el presente documento se lleva cabo una revisión actualizada de la PE. Se describen los criterios diagnósticos y la fisiopatología de la enfermedad. El objetivo principal del documento es revisar los nuevos marcadores bioquímicos que pueden ser de utilidad en la práctica clínica para la predicción y el diagnóstico de la PE, así como los distintos métodos mediante los cuales se puede llevar a cabo su determinación

Pre-eclampsia (PE) is one of the leading causes of maternal and perinatal mortality in the world. In developed countries, studies point to a significant increase in the incidence of PE in the last decade, partly due to the increase in the prevalence in the general population of diseases that affect vascular function, such as diabetes. chronic hypertension, or kidney disease. An updated review of PE is presented in this article. The diagnostic criteria and the pathophysiology of the disease are described. The main objective of the document is to review the new biochemical markers that may be useful in clinical practice for the prediction and diagnosis of PE, as well as the different methods by which yey can be determined

Tunicamycin Sensitivity-Suppression by High Gene Dosage Reveals New Functions of the Yeast Hog1 MAP Kinase.

In the yeast Saccharomyces cerevisiae, components of the High Osmolarity Glycerol (HOG) pathway are important for the response to diverse stresses including response to endoplasmic reticulum stress (ER stress), which is produced by the accumulation of unfolded proteins in the lumen of this organelle. Accumulation of unfolded proteins may be due to the inhibition of protein N-glycosylation, which can be achieved by treatment with the antibiotic tunicamycin (Tn). In this work we were interested in finding proteins involved in the ER stress response regulated by Hog1, the mitogen activated protein kinase (MAPK) of the HOG pathway. A high gene dosage suppression screening allowed us to identify genes that suppressed the sensitivity to Tn shown by a hog1Δ mutant. The suppressors participate in a limited number of cellular processes, including lipid/carbohydrate biosynthesis and protein glycosylation, vesicle-mediated transport and exocytosis, cell wall organization and biogenesis, and cell detoxification processes. The finding of suppressors Rer2 and Srt1, which participate in the dolichol biosynthesis pathway revealed that the hog1Δ strain has a defective polyprenol metabolism. This work uncovers new genetic and functional interactors of Hog1 and contributes to a better understanding of the participation of this MAPK in the ER stress response.

The Unfolded Protein Response Pathway in the Yeast Kluyveromyces lactis. A Comparative View among Yeast Species.

Eukaryotic cells have evolved signalling pathways that allow adaptation to harmful conditions that disrupt endoplasmic reticulum (ER) homeostasis. When the function of the ER is compromised in a condition known as ER stress, the cell triggers the unfolded protein response (UPR) in order to restore ER homeostasis. Accumulation of misfolded proteins due to stress conditions activates the UPR pathway. In mammalian cells, the UPR is composed of three branches, each containing an ER sensor (PERK, ATF6 and IRE1). However, in yeast species, the only sensor present is the inositol-requiring enzyme Ire1. To cope with unfolded protein accumulation, Ire1 triggers either a transcriptional response mediated by a transcriptional factor that belongs to the bZIP transcription factor family or an mRNA degradation process. In this review, we address the current knowledge of the UPR pathway in several yeast species: Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida glabrata, Cryptococcus neoformans, and Candida albicans. We also include unpublished data on the UPR pathway of the budding yeast Kluyveromyces lactis. We describe the basic components of the UPR pathway along with similarities and differences in the UPR mechanism that are present in these yeast species.

Unfolding the Endoplasmic Reticulum of a Social Amoeba: Dictyostelium discoideum as a New Model for the Study of Endoplasmic Reticulum Stress.

The endoplasmic reticulum (ER) is a membranous network with an intricate dynamic architecture necessary for various essential cellular processes. Nearly one third of the proteins trafficking through the secretory pathway are folded and matured in the ER. Additionally, it acts as calcium storage, and it is a main source for lipid biosynthesis. The ER is highly connected with other organelles through regions of membrane apposition that allow organelle remodeling, as well as lipid and calcium traffic. Cells are under constant changes due to metabolic requirements and environmental conditions that challenge the ER network’s maintenance. The unfolded protein response (UPR) is a signaling pathway that restores homeostasis of this intracellular compartment upon ER stress conditions by reducing the load of proteins, and by increasing the processes of protein folding and degradation. Significant progress on the study of the mechanisms that restore ER homeostasis was achieved using model organisms such as yeast, Arabidopsis, and mammalian cells. In this review, we address the current knowledge on ER architecture and ER stress response in Dictyostelium discoideum. This social amoeba alternates between unicellular and multicellular phases and is recognized as a valuable biomedical model organism and an alternative to yeast, particularly for the presence of traits conserved in animal cells that were lost in fungi.

The European eel may tolerate multiple infections at a low biological cost.

Most animals are concurrently infected with multiple parasites, and interactions among them may influence both disease dynamics and host fitness. However, the sublethal costs of parasite infections are difficult to measure and the effects of concomitant infections with multiple parasite species on individual physiology and fitness are poorly described for wild hosts. To understand the costs of co-infection, we investigated the relationships among 189 European eel (Anguilla anguilla) from Mar Menor, parasites (richness and intensity) and eel's 'health status' (fluctuant asymmetry, splenic somatic index and the scaled mass index) by partial least squares regression. We found a positive relationship with 44% of the health status variance explained by parasites. Contracaecum sp. (Nematoda: Anisakidae) was the strongest predictor variable (44·72%) followed by Bucephalus anguillae (Platyhelminthes: Bucephalidae), (29·26%), considered the two most relevant parasites in the analysis. Subsequently, 15·67 and 12·01% of the response variables block were explained by parasite richness and Deropristis inflata (Platyhelminthes: Deropristiidae), respectively. Thus, the presence of multiple parasitic exposures with little effect on condition, strongly suggests that eels from Mar Menor tolerate multiparasitism.

Intervenciones psicológicas para el manejo y reducción de estrés en pacientes hipertensos: una revisión sobre su efectividad / Psychological interventions on stress management and reduction for hypertensive patients: a review of their effectiveness

Resumen La hipertensión está considerada como una de las principales problemáticas de salud pública, pues es una enfermedad crónica asintomática caracterizada por una elevación de presión arterial, en la que inciden los niveles de estrés que percibe el paciente y cuyas consecuencias pueden ser devastadoras tanto en la salud física como emocional de este grupo. Se realizó una revisión analítica enfocada a la efectividad de diversos tipos de intervención psicológica, para disminuir los niveles de presión sistólica, controlar el nivel de la presión diastólica, disminuir la percepción del estrés de los sujetos y propiciar una mayor adherencia al tratamiento. La búsqueda se realizó en la base de datos Springer, donde 50 artículos cumplieron con los criterios de exclusión y de inclusión, para el periodo 2000-2013. La revisión arrojó una mayor inclinación hacia las intervenciones de tipo conductual (38%), sin embargo, las intervenciones cognitivo-conductuales fueron las más eficaces para disminuir los niveles de estrés y generar la reducción más significativa en presión arterial, con un 100% de resultados positivos, mientras que solo el 68.4% de los estudios conductuales reportó una mejoría.

Abstract Hypertension an asymptomatic chronic disease characterized by elevated blood pressure, is considered a public health problem, affected by stress levels perceived by the patient, with physical and emotional health consequences that can be devastating for this population. This study presents an analytical review focused on the effectiveness of different types of psychological intervention to reduce systolic blood pressure levels, controlling the level of diastolic pressure, decreasing stress perception of subjects and fostering greater adherence. The search was conducted by means of the Springer database, with 50 articles selected on the basis of the inclusion and exclusion criteria for the period 2000-2013. Results showed greater inclination towards behavioral type interventions (38%), while cognitive-behavioral interventions were the most effective for decreasing stress levels and producing the most significant reduction in blood pressure, 100% of the studies based on this type of intervention showed positive results, while the behavioral type only registered 68.4% of success.

Un Protocolo para Observar cómo los Profesores Ayudan a sus Alumnos cuando Leen Textos en el Aula / A Protocol for Observation of how Students are Helped by Teachers when Reading Texts in Class

En este trabajo se propone y se justifica un sistema para analizar cómo transcurren las lecturas colectivas en las que profesores y alumnos abordan la lectura y la interpretación de un texto. El sistema conlleva analizar seis tipos de elementos, dispuestos en sucesivas capas que conforman el contexto de la actividad: la función que cumplen las lecturas, cómo se organiza globalmente la actividad, cómo se organiza localmente, el tipo de planes que se proponen, las ayudas locales que se proporcionan, y la retórica del texto. Se asume que esas capas canalizan y conforman la actividad mental y social de los alumnos. De cada una de ellas se propone un esquema para el análisis con guías específicas para interpretar los datos. Todo ello se ejemplifica en un caso real del que se desprenden algunas consecuencias para la intervención educativa (AU)

In this paper, a system for analysis of whole-group reading lessons (activity in which the teacher and his/her whole class read and interpret a text) is proposed and discussed. The system focuses on six elements to be analyzed: the function (role) of whole group reading within a curricular unit, the way in which this activity is organized globally, the way in which the interaction (between teacher and pupils) is structured locally, the kind of planning which takes place, the local aids provided by the teacher, and the rhetorical characteristics of the texts. These different elements form the successive layers of the context of teacher-aided reading activities, and it is assumed that these layers channel and make up the pupils´ mental and social activity. A guide is suggested to analyze each of them (with specific guidelines to interpret data). Finally, all this is illustrated with a case study from which implications are drawn for educational intervention (AU)

Ghrelin inhibits proliferation and increases T-type Ca2+ channel expression in PC-3 human prostate carcinoma cells.

Ghrelin is a multifunctional peptide hormone with roles in growth hormone release, food intake and cell proliferation. With ghrelin now recognized as important in neoplastic processes, the aim of this report is to present findings from a series of in vitro studies evaluating the cellular mechanisms involved in ghrelin regulation of proliferation in the PC-3 human prostate carcinoma cells. The results showed that ghrelin significantly decreased proliferation and induced apoptosis. Consistent with a role in apoptosis, an increase in intracellular free Ca(2+) levels was observed in the ghrelin-treated cells, which was accompanied by up-regulated expression of T-type voltage-gated Ca(2+) channels. Interestingly, T-channel antagonists were able to prevent the effects of ghrelin on cell proliferation. These results suggest that ghrelin inhibits proliferation and may promote apoptosis by regulating T-type Ca(2+) channel expression.

Aminoglucosidos en la infección urinaria / Aminoglucoids in urinary infections

Se realizó un estudio descriptivo retrospectivo de cohorte de todos los urocultivos con antibiograma realizados durante el año 2002 en el Hospital Luis Aldana Palomino, para determinar la frecuencia de resistencia bacteriana a los aminoglucósidos de uso común en el tratamiento de las infecciones urinarias complicadas. Se trabajó para un índice de confianza del 95 por ciento por estadígrafo CHI-cuadrado. Encontrando niveles de resistencia superiores al 10 por ciento estimado para los aminoglucósidos en general. La amikacina fue el fármaco más efectivo, mientras que la kanamicina y la gentamicina mostraron un elevado índice de resistencia, especialmente la gentamicina en presencia de cepas de Echerichia coli, donde resultó clínica y estadísticamente significativo ( a <0,05) al compararse con la amikacina. Se recomienda el uso racional de los antimicrobianos en concordancia con el antibiograma (AU)

A descriptive and retrospective cohort study in all antibiogran midstream realized during the 2002 year in the Luis Aldana Palomino Hospital was made. The bacterial resistance to common use aminoglucosides in the treatment of complicated kidney infection was found. Chi Cuadrado test with 95 per cent confidence index was use. The aminoglucosides in general showed a resistance level over than 10 per cent. The most effective antibiotic was amikacin, on the other hands, kanamicina and gentamicina showed an elevated resistance index, especially gentamicina from E. coli . Clinically and statistically significative difference ( p < 0,05 ) to amikacin was found (AU)

Nutrición en la etiología y tratamiento del cáncer / Nutrition in the etiology and therapy of cancer

La nutrición juega papel importante en la historia natural del cáncer. La dieta está involucrada en la carcinogénesis a través de mecanismos que son cada vez más claros. Se considera que por lo menos el 35 por ciento del total de casos de cáncer se asocian a la dieta y que cáncer y caquexia están entre las causas más comunes de muerte por enfermedad maligna. Esta revisión tiene el propósito de mostrar la relación del cáncer con la nutrición desde sus cuatro perspectivas: 1. La dieta como factor etiológico; 2. Las alteraciones nutricias causadas por la enfermedad; 3. Las alteraciones nutricias causadas por los tratamientos; y La alimentación del paciente con cáncer. Destacado además, la importancia que tiene la terapia nutricia en este especial grupo de pacientes.

Aplicación del proceso de enfermería en el Servicio de Enfermedades Respiratorias Agudas / Application of the nursing process in the Service of Acute Respiratory Diseases

Desde el valor que posee la recuperación de los pacientes y el desarrollo de las prácticas de enfermería, se estudiaron 37 niños menores de 1 año ingresados en el Servicio de Enfermedades Respiratorias agudas del Hospital Infantil Sur Docente de Santiago de Cuba durante los meses marzo-abril de 1987. La investigación se fundamentó en el proceso de atención de enfermería, para conocer el comportamiento y resultado de su aplicación en una sala cuya plantilla cubría los indicadores actuales. Se pudo conocer que con el recurso humano con que contaba el servicio resultó factible llevar a cabo dicho proceso, con el que se logró una más rápida rehabilitación de estos enfermos, acorde con el plan de cuidado realizado; la relación enfermera-paciente se puso de manifiesto en todos los pacientes estudiados, entre los que predominaron los del grupo de edades de 6 a 9 meses

Aplicación del proceso de enfermería en el Servicio de Enfermedades Respiratorias Agudas / Application of the nursing process in the Service of Acute Respiratory Diseases

Desde el valor que posee la recuperación de los pacientes y el desarrollo de las prácticas de enfermería, se estudiaron 37 niños menores de 1 año ingresados en el Servicio de Enfermedades Respiratorias agudas del Hospital Infantil Sur Docente de Santiago de Cuba durante los meses marzo-abril de 1987. La investigación se fundamentó en el proceso de atención de enfermería, para conocer el comportamiento y resultado de su aplicación en una sala cuya plantilla cubría los indicadores actuales. Se pudo conocer que con el recurso humano con que contaba el servicio resultó factible llevar a cabo dicho proceso, con el que se logró una más rápida rehabilitación de estos enfermos, acorde con el plan de cuidado realizado; la relación enfermera-paciente se puso de manifiesto en todos los pacientes estudiados, entre los que predominaron los del grupo de edades de 6 a 9 meses