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1.
Science ; 372(6547): 1192-1196, 2021 06 11.
Artigo em Inglês | MEDLINE | ID: mdl-34112691

RESUMO

Extending the framework of statistical physics to the nonequilibrium setting has led to the discovery of previously unidentified phases of matter, often catalyzed by periodic driving. However, preventing the runaway heating that is associated with driving a strongly interacting quantum system remains a challenge in the investigation of these newly discovered phases. In this work, we utilize a trapped-ion quantum simulator to observe the signatures of a nonequilibrium driven phase without disorder-the prethermal discrete time crystal. Here, the heating problem is circumvented not by disorder-induced many-body localization, but rather by high-frequency driving, which leads to an expansive time window where nonequilibrium phases can emerge. Floquet prethermalization is thus presented as a general strategy for creating, stabilizing, and studying intrinsically out-of-equilibrium phases of matter.

2.
Nature ; 551(7682): 601-604, 2017 11 29.
Artigo em Inglês | MEDLINE | ID: mdl-29189781

RESUMO

A quantum simulator is a type of quantum computer that controls the interactions between quantum bits (or qubits) in a way that can be mapped to certain quantum many-body problems. As it becomes possible to exert more control over larger numbers of qubits, such simulators will be able to tackle a wider range of problems, such as materials design and molecular modelling, with the ultimate limit being a universal quantum computer that can solve general classes of hard problems. Here we use a quantum simulator composed of up to 53 qubits to study non-equilibrium dynamics in the transverse-field Ising model with long-range interactions. We observe a dynamical phase transition after a sudden change of the Hamiltonian, in a regime in which conventional statistical mechanics does not apply. The qubits are represented by the spins of trapped ions, which can be prepared in various initial pure states. We apply a global long-range Ising interaction with controllable strength and range, and measure each individual qubit with an efficiency of nearly 99 per cent. Such high efficiency means that arbitrary many-body correlations between qubits can be measured in a single shot, enabling the dynamical phase transition to be probed directly and revealing computationally intractable features that rely on the long-range interactions and high connectivity between qubits.

3.
Philos Trans A Math Phys Eng Sci ; 375(2108)2017 Dec 13.
Artigo em Inglês | MEDLINE | ID: mdl-29084886

RESUMO

Linear arrays of trapped and laser-cooled atomic ions are a versatile platform for studying strongly interacting many-body quantum systems. Effective spins are encoded in long-lived electronic levels of each ion and made to interact through laser-mediated optical dipole forces. The advantages of experiments with cold trapped ions, including high spatio-temporal resolution, decoupling from the external environment and control over the system Hamiltonian, are used to measure quantum effects not always accessible in natural condensed matter samples. In this review, we highlight recent work using trapped ions to explore a variety of non-ergodic phenomena in long-range interacting spin models, effects that are heralded by the memory of out-of-equilibrium initial conditions. We observe long-lived memory in static magnetizations for quenched many-body localization and prethermalization, while memory is preserved in the periodic oscillations of a driven discrete time crystal state.This article is part of the themed issue 'Breakdown of ergodicity in quantum systems: from solids to synthetic matter'.

4.
Nature ; 543(7644): 217-220, 2017 03 08.
Artigo em Inglês | MEDLINE | ID: mdl-28277505

RESUMO

Spontaneous symmetry breaking is a fundamental concept in many areas of physics, including cosmology, particle physics and condensed matter. An example is the breaking of spatial translational symmetry, which underlies the formation of crystals and the phase transition from liquid to solid. Using the analogy of crystals in space, the breaking of translational symmetry in time and the emergence of a 'time crystal' was recently proposed, but was later shown to be forbidden in thermal equilibrium. However, non-equilibrium Floquet systems, which are subject to a periodic drive, can exhibit persistent time correlations at an emergent subharmonic frequency. This new phase of matter has been dubbed a 'discrete time crystal'. Here we present the experimental observation of a discrete time crystal, in an interacting spin chain of trapped atomic ions. We apply a periodic Hamiltonian to the system under many-body localization conditions, and observe a subharmonic temporal response that is robust to external perturbations. The observation of such a time crystal opens the door to the study of systems with long-range spatio-temporal correlations and novel phases of matter that emerge under intrinsically non-equilibrium conditions.

5.
Science ; 343(6168): 269-72, 2014 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-24356114

RESUMO

The Standard Model of particle physics is known to be incomplete. Extensions to the Standard Model, such as weak-scale supersymmetry, posit the existence of new particles and interactions that are asymmetric under time reversal (T) and nearly always predict a small yet potentially measurable electron electric dipole moment (EDM), d(e), in the range of 10(-27) to 10(-30) e·cm. The EDM is an asymmetric charge distribution along the electron spin (S(→)) that is also asymmetric under T. Using the polar molecule thorium monoxide, we measured d(e) = (-2.1 ± 3.7stat ± 2.5syst) × 10(-29) e·cm. This corresponds to an upper limit of |d(e)| < 8.7 × 10(-29) e·cm with 90% confidence, an order of magnitude improvement in sensitivity relative to the previous best limit. Our result constrains T-violating physics at the TeV energy scale.

6.
Am Ind Hyg Assoc J ; 39(9): 717-22, 1978 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-727117

RESUMO

This procedure describes a field method for determining operator noise exposures that cannot be assessed from single sound level meter readings. Noise exposures that should be evaluated by this method are those characterized by time-varying operator position sound levels--sound levels that change by three decibels or more while the meter is being read. The method is based on statistical concepts and requires multiple readings for a sample period whose length is prescribed by the desired precision of the results. This new procedure compares well with the theoretical accuracy of the best dosimeters. The actual performance of the new method has been shown to be better than the actual performance of the dosimeters.


Assuntos
Exposição Ambiental , Ruído Ocupacional , Ruído , Humanos
7.
Cancer ; 39(4 Suppl): 1850-5, 1977 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-192437

RESUMO

Clustering of cases of feline lymphosarcoma (LSA) has been observed by veterinarians for many years. In 1964 it was discovered that feline LSA was caused by an oncornavirus, the feline leukemia virus (FeLV). In 1970, a simple, indirect immunoflourescent antibody (IFA) test for FeLV was developed which enabled large numbers of cats, living in their natural (household) environments, to be tested for the virus. In one study, over 2,000 cats were tested and the results showed conclusively that FeLV is a contagious agent for cats. This finding was independently confirmed by several other investigators using different testing procedures. After discovering the contagious nature of FeLV a test and removal program was devised which successfully prevents the spread of FeLV and the development of FeLV diseases in the pet cat population. There is, at present, no evidence that FeLV infects humans living with FeLV infected cats.


Assuntos
Doenças do Gato/transmissão , Vírus da Leucemia Felina , Linfoma não Hodgkin/veterinária , Infecções Tumorais por Vírus/veterinária , Animais , Antígenos de Neoplasias , Antígenos Virais , Capsídeo/imunologia , Doenças do Gato/etiologia , Doenças do Gato/imunologia , Gatos , Métodos Epidemiológicos , Feminino , Humanos , Vírus da Leucemia Felina/imunologia , Linfoma não Hodgkin/etiologia , Linfoma não Hodgkin/imunologia , Linfoma não Hodgkin/transmissão , Masculino
12.
Cancer Res ; 36(2 pt 2): 582-8, 1976 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-175919

RESUMO

The feline leukemia virus (FeLV) was discovered in 1964 in a cluster of cats with lymphosarcoma. The observed clustering of cases of feline lymphosarcoma suggested that FeLV was an infectious agent for cats. The development of a simple immunofluorescent test for FeLV permitted a seroepidemiological study to be undertaken on the distribution of the virus in cats living in their natural environment. Over 2000 cats were tested, and the results showed conclusively that FeLV is an infectious agent for cats. This finding has now been independently confirmed using three different test procedures. After the infectious nature of FeLV was discovered, a simple FeLV test and removal program was devised to control the spread of the virus in the natural environment. The spread of FeLV was controlled in 45 households by removing the FeLV-infected cats, while in 25 households, where the infected cats were left in contact with the uninfected cats, 12% of the uninfected cats became infected. The ultimate control of FeLV awaits the development of an effective FeLV vaccine, which now seems feasible since we have already experimentally immunized some cats with attenuated FeLV. Although FeLV is infectious for cats there is no evidence that FeLV can infect humans.


Assuntos
Doenças do Gato/etiologia , Vírus da Leucemia Felina , Linfoma não Hodgkin/veterinária , Animais , Anticorpos Antivirais/análise , Antígenos Virais/análise , Doenças do Gato/transmissão , Gatos , Controle de Doenças Transmissíveis , Reservatórios de Doenças , Humanos , Vírus da Leucemia Felina/imunologia , Vírus da Leucemia Felina/patogenicidade , Linfoma não Hodgkin/transmissão , Testes de Neutralização , Sorotipagem , Infecções Tumorais por Vírus/etiologia
15.
Bibl Haematol ; (40): 67-74, 1975.
Artigo em Inglês | MEDLINE | ID: mdl-169834

RESUMO

Traditionally, cancer has not been considered an infectious disease although some multiple cases of leukemia in man and cattle have been reported. The discovery that feline lymphosarcoma was associated with an RNA virus (feline leukemia virus(FeLV)) meant that infectious transmission of the disease was a possibility. The critical question was whether the predominant method of transmission from one animal to another was 'vertical' (via the gametes) or 'horizontal' (via contagion or infection). A number of epidemiological studies have shown that the chances of healthy cats contracting lymphosarcoma are greatly increased when a cat with the disease lives in close proximity. It does not matter whether the healthy cats are related to the sick animal or not. It has also been established that viremic normal cats have an approximately 900 times greater chance of developing leukemia than cats whose FeLV status is unknown. Infectious FeLV is present in the excretions and blood of viremic animals. In the natural environment, feline lymphosarcoma occurs in clusters. The results in pet cats have been supported by experiments with cat colonies under controlled conditions and prove that horizontal transmission of FeLV occurs. This does not mean that epigenetic (infection in utero or via the milk) or vertical transmission cannot also occur. It should be possible to break the cycle of horizontal transmission of the virus by vaccination and thus control FeLV-related diseases.


Assuntos
Doenças do Gato/transmissão , Vírus da Leucemia Felina , Linfoma não Hodgkin/veterinária , Animais , Sangue/microbiologia , Doenças do Gato/microbiologia , Gatos , Surtos de Doenças/veterinária , Reservatórios de Doenças/veterinária , Vetores de Doenças , Feminino , Vírus da Leucemia Felina/isolamento & purificação , Linfoma não Hodgkin/microbiologia , Linfoma não Hodgkin/transmissão , Troca Materno-Fetal , Leite/microbiologia , Gravidez , Saliva/microbiologia , Urina/microbiologia
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