Assuntos
Doença de Crohn/tratamento farmacológico , Resistência a Medicamentos , Tromboflebite/complicações , Dor Abdominal/etiologia , Adalimumab , Adulto , Anti-Inflamatórios não Esteroides/uso terapêutico , Anticorpos Monoclonais Humanizados/uso terapêutico , Doença de Crohn/complicações , Humanos , Masculino , Tromboflebite/diagnóstico por imagem , UltrassonografiaRESUMO
Dengue hemorrhagic fever is characterized by the presence of a capillary leak syndrome. Its pathogenesis is presumed to differ from that of classical dengue fever (DF) and to be associated with secondary dengue infection. Returning travelers given a diagnosis of DF were evaluated for capillary leakage with abdominal sonography. Data were compared between travelers with primary/secondary infection defined by epidemiologic and serologic parameters. A total of 12 (34.3%) of 35 patients had sonographic signs of capillary leakage. Most (85%) patients with capillary leakage had classical DF. Capillary leak was diagnosed in 32% of primary dengue cases and in 40% of secondary dengue cases (P = 0.69). The two patients given a diagnosis of dengue hemorrhagic fever had primary infections. The high prevalence of capillary leakage among travelers, most of them with primary exposure to dengue, calls into question the importance of secondary infection in causing capillary leakage in dengue infection.
Assuntos
Capilares/patologia , Síndrome de Vazamento Capilar/patologia , Dengue Grave/diagnóstico , Dengue Grave/patologia , Adulto , Síndrome de Vazamento Capilar/epidemiologia , Síndrome de Vazamento Capilar/etiologia , Coinfecção/complicações , Coinfecção/patologia , Feminino , Humanos , Masculino , Prevalência , Estudos Prospectivos , Dengue Grave/complicações , Dengue Grave/epidemiologia , Adulto JovemRESUMO
OBJECTIVE: To assess the incidence of short-term outcomes of low birth weight infants (= 1,750 g) exposed prenatally to either dexamethasone or betamethasone. METHODS: We retrospectively analyzed a cohort comprising 550 infants who were born alive at our center during the period January 1999 through December 2001, who weighed 1,750 g or less at birth, and who were exposed to prenatal steroid treatment. We compared brain ultrasound findings, such as intraventricular hemorrhage and cystic periventricular leukomalacia (PVL), as well as other clinical findings, including respiratory distress syndrome (RDS), necrotizing enterocolitis, retinopathy of prematurity, and bronchopulmonary dysplasia, for all premature infants whose mothers received either dexamethasone (from January 1, 1999 to June 30, 2000, n = 263) or betamethasone (July 1, 2000 to December 31, 2001, n = 287). RESULTS: Patient characteristics (mothers and infants) were the same in both groups, with the exception of the number of steroid courses administered, the number of women with premature rupture of membranes (defined as > 24 hours), and the number of women who had received tocolysis. No significant difference was found between the 2 groups with respect to intraventricular hemorrhage and cystic PVL frequencies. No significant differences were found in the incidence of short-term outcomes examined, despite the fact that the dexamethasone group was exposed to a statistically significantly greater number of courses than the betamethasone group. CONCLUSION: There seem to be no advantages to maternal antenatal treatment with betamethasone compared with dexamethasone in reducing the risk of PVL in low birth weight (= 1,750 g) infants. Both drugs have the same effect on all short-term outcome parameters checked.
Assuntos
Betametasona/uso terapêutico , Dexametasona/uso terapêutico , Glucocorticoides/uso terapêutico , Recém-Nascido de Baixo Peso , Doenças do Recém-Nascido/prevenção & controle , Feminino , Humanos , Recém-Nascido , Exposição Materna , Estudos Retrospectivos , Fatores de TempoRESUMO
Epidermoid cyst, a tumorlike lesion, is a rare benign testicular tumor with typical, distinctive ultrasonographic appearance. When the preoperative features are highly suggestive of epidermoid cyst, testicular sparing surgery after strict oncologic guidelines is warranted. The authors report a case of a preoperatively suspected epidermoid cyst in an adolescent and review the literature concerning the changing paradigm of management.