Escala de conocimientos sobre úlceras de pie diabético CUPD-35: elaboración y propiedades psicométricas en enfermeras de Colombia / Diabetic Foot Ulcer Knowledge Scale CUPD-35: development and psychometric properties on Colombian nurses

Introducción: Las enfermeras tienen un papel esencial en la prevención y en el manejo de las úlceras de pie diabético, por lo que es importante su formación para que tengan conocimientos actualizados. Disponer de escalas para medir de forma fiable estos conocimientos es de utilidad para los programas formativos. Objetivo: Elaborar y obtener propiedades psicométricas de una escala para medir los conocimientos de enfermeras sobre prevención y tratamiento de úlceras de pie diabético. Metodología: Primera fase de elaboración de los ítems de la escala y validación de contenido por panel de expertos. Segunda fase de prueba de campo mediante encuesta a una muestra de 500 enfermeras de hospital y clínicas de heridas en Colombia. Se realizó un análisis mediante modelos de Rasch y validación de constructo mediante test en grupos conocidos. Resultados: La versión inicial de la escala con 48 ítems tuvo adecuada validez de contenido. Tras la prueba de campo y el análisis Rasch se obtuvo la versión final con 35 ítems (CUPD-35) con buenos índices de ajuste y alta fiabilidad (0,97). La puntuación media de conocimientos en esta muestra de enfermeras fue de 28,2 (un 80,2% de la máxima puntuación), lo que indica un buen nivel de conocimientos. Conclusiones: La escala CUPD-35 es un instrumento fiable y válido para medir conocimientos sobre úlceras de pie diabético en enfermerashispanohablantes.(AU)

Introduction: Nurses play an essential role in the prevention and treatment of diabetic foot ulcers, so it is important that they are trained to achieve up-to-date knowledge. Appropriate and reliable tools to measure knowledge are useful for planning training programmes. Objective: To develop and obtain the psychometric properties of a new scale to measure nurses’ knowledge of diabetic foot ulcers prevention and treatment. Methodology: A first phase of item development and content validation by an expert panel. A second phase with a survey of a sample of 500 nurses in Colombia working in hospitals or wound clinics. Analysis using Rasch models and assessment of construct validity by a test of known groups. Results: The initial 48-item version of the scale showed adequate content validity. The survey and Rasch analysis resulted in the final version with 35 items (CUPD-35) with good fit indices and high reliability (0.97). The mean knowledge score of this sample of nurses was 28.2 (80.2% of the maximum score), which means a good level of knowledge. Conclusions: The CUPD-35 scale is a reliable and valid tool for measuring knowledge of diabetic foot ulcers in Spanish-speaking nurses.(AU)

Insights into the Y chromosome human diversity in Uruguay.

BACKGROUND: With regard to the origin of its population and microevolutionary processes, Uruguay exhibits distinctive features that distinguish it from other countries in Latin America, while at the same time sharing several similarities. In this article, we will focus on the variability of paternal genetic lineages in two geographical regions with different histories that can be considered as examples of distinct populations for the continent. In general terms, the genetic diversity is a result of different demographic processes related to the American conquest and colonisation. These resulted in distinct ancestral components which vary geographical and depend on the distribution by sex within these components. In Uruguay, native maternal haplogroups are significantly more frequent in the North. Although there are several studies about the geneticvariability of Uruguay, little is known about male genetic lineages. AIMS: The aim of this work is to present an updated study of the male genetic variability of the Uruguayan population. METHODS: We analyzed 13 biallelic markers and 27 STRs located in the male-specific region of the Y chromosome for 157 males: 98 from the capital, Montevideo, and 59 from Tacuarembó. RESULTS: Almost all haplogroups found in both locations are European (99% and 93.2% respectively). One Sub-Saharan African haplogroup was found in Montevideo (1%) and 2 in Tacuarembó (3%), while Native haplogroups were found only in Tacuarembó, evidencing a strong sex-biased admixture. By crossing genetic and genealogical information we could relate European haplogroups with different waves and times of migrations. DISCUSSION: Network analysis indicated a very diverse male population, suggesting that European migrants came from heterogeneous geographic locations and in different waves. Tacuarembó has closer population affinities with Iberian populations while Montevideo is more diverse. Male population expansion expansion, can be explained by the large number of migrants that arrived during the XIX century and the first half of the XX century. CONCLUSIONS: The Uruguayan male gene pool is the result of several migration waves with diverse origins, with strong sex-biased admixture that can be explained by the European migration, the violence against the indigenous males, and the segregation of the Africansadmixture that can be explained due to European migration, violence against Natives, and segregation against African males.admixture that can be explained due to European migration, violence against Natives, and segregation against African males.admixture that can be explained due to European migration, violence against Natives, and segregation against African males.admixture that can be explained due to European migration, violence against Natives, and segregation of hte Africans.

Room Temperature Polymorphism in WO3 Produced by Resistive Heating of W Wires.

Polymorphous WO3 micro- and nanostructures have been synthesized by the controlled Joule heating of tungsten wires under ambient conditions in a few seconds. The growth on the wire surface is assisted by the electromigration process and it is further enhanced by the application of an external electric field through a pair of biased parallel copper plates. In this case, a high amount of WO3 material is also deposited on the copper electrodes, consisting of a few cm2 area. The temperature measurements of the W wire agrees with the values calculated by a finite element model, which has allowed us to establish the threshold density current to trigger the WO3 growth. The structural characterization of the produced microstructures accounts for the γ-WO3 (monoclinic I), which is the common stable phase at room temperature, along with low temperature phases, known as δ-WO3 (triclinic) on structures formed on the wire surface and ϵ-WO3 (monoclinic II) on material deposited on external electrodes. These phases allow for a high oxygen vacancies concentration, which is interesting in photocatalysis and sensing applications. The results could help to design experiments to produce oxide nanomaterials from other metal wires by this resistive heating method with scaling-up potential.

A Digital Tool for Measuring Healing of Chronic Wounds Treated with an Antioxidant Dressing: A Case Series.

(1) Abstract: Wound monitoring is an essential aspect in the evaluation of wound healing. This can be carried out with the multidimensional tool HELCOS, which develops a quantitative analysis and graphic representation of wound healing evolution via imaging. It compares the area and tissues present in the wound bed. This instrument is used for chronic wounds in which the healing process is altered. This article describes the potential use of this tool to improve the monitoring and follow-up of wounds and presents a case series of various chronic wounds with diverse etiology treated with an antioxidant dressing. (2) Methods: A secondary analysis of data from a case series of wounds treated with an antioxidant dressing and monitored with the HELCOS tool. (3) Results: The HELCOS tool is useful for measuring changes in the wound area and identifying wound bed tissues. In the six cases described in this article, the tool was able to monitor the healing of the wounds treated with the antioxidant dressing. (4) Conclusions: the monitoring of wound healing with this multidimensional HELCOS tool offers new possibilities to facilitate treatment decisions by healthcare professionals.

Realfood and Cancer: Analysis of the Reliability and Quality of YouTube Content.

This study analyzes the quality and reliability of videos related to nutrition and cancer on YouTube. STUDY DESIGN: An observational, retrospective, cross-sectional, time-limited study analyzing activity on the social network YouTube was proposed. METHODS: The information from the videos was extracted through an API search tool, using the NodeXL software. The criteria to select the videos on YouTube were the keywords "real food", "realfood", and "cancer" and the hashtags #realfood and #cancer were present, videos in English and videos available on 1 December 2022. RESULTS: The DISCERN value in the total number of videos viewed was 2.25 (±0.88) points, indicating low reliability. The videos uploaded by HRU represented only 20.8%. Videos suggesting that the use of foods defined as "real food" could cure cancer without the intervention of any other treatment accounted for 12.5%. Videos that provided external links to scientific/technical evidence verifying the information represented only 13.89% of the total number of videos. Of these videos, 70% corresponded to HRU. The DISCERN value for videos from HRU users was 3.05 (0.88), a value that reflects a good reliability of videos from these users. CONCLUSIONS: This study provides information on the content and quality of the videos that we can find on YouTube. We found videos of non-health users who do not base their content on any scientific evidence, with the danger that this entails for the population, but it also highlights that the videos published by HRU have greater reliability and quality, being better perceived by the population, so it is important to encourage healthcare professionals and health institutions to share verified information on YouTube.

Analysis of Healthcare Professionals' and Institutions' Roles in Twitter Colostomy Information.

Social media represents a powerful tool for disseminating verified health information on topics such as colostomy, and the roles of healthcare professionals and institutions to ensure the veracity of the information conveyed is increasingly relevant. The main objectives of this study were to analyze the roles of these healthcare professionals and institutions in the conversation about colostomy, without being framed in a specific health communication campaign, and to know the use of reliable information in the conversation. The study was carried out by analyzing Twitter messages containing the hashtag "colostomy" and "Chron" between the 1 January and the 30 April 2022. It was conducted using the NodeXL software, focusing on content analysis of tweets and users' accounts. The results show that accounts with healthcare activity influence the impressions generated on the network (p = 0.018), finding that nurses are the most active healthcare professionals (22.24%) also having a significant effect on the overall network interactions (p = 0.022). In contrast, we found that institutions do not actively participate on the network. We emphasize the responsibility of institutions for health education and the need for professionals to improve communication skills on social networks, but also the need to improve communication skills on social media to support public health campaigns through these increasingly important channels.

DNA polymorphisms associated with lactase persistence, self-perceived symptoms of lactose intolerance, milk and dairy consumption, and ancestry, in the Uruguayan population.

Uruguay has one of the highest per capita milk intakes worldwide, even with a limited supply of lactose-free products; furthermore, the admixed nature of its population is well known, and various frequencies of lactase persistence (LP) are observed in the source populations. We aimed to contribute to the understanding of the relation between allelic variants associated with LP, milk consumption, digestive symptoms, and genetic ancestry in the Uruguayan population. Samples of saliva or peripheral blood were collected from 190 unrelated individuals from two regions of Uruguay, genotypes for polymorphic sites in a fragment within the LCT enhancer were determined and allelic frequencies calculated in all of them. Data were collected on frequency of milk and dairy consumption and self-reported symptoms in a subsample of 153 individuals. Biparental and maternal ancestry was determined by analyzing individual ancestry markers and mitochondrial DNA. Twenty-nine percentage of individuals reported symptoms attributed to the ingestion of fresh milk, with abdominal pain, bloating and flatulence being the most frequent. European LP-associated allele T-13910 showed a frequency of 33%, while other LP-associated alleles like G-13915 and T-14011 were observed in very low frequencies. Associations between self-reported symptoms, fresh milk intake, and C/T-13910 genotype were statistically significant. No evidence of association between genetic ancestry and C/T-13910 was found, although individuals carrying one T-13910 allele appeared to have more European ancestry. In conclusion, the main polymorphism capable of predicting lactose intolerance in Uruguayans is C/T-13910, although more studies are required to unravel the relation between genotype and lactase activity, especially in heterozygotes.

Uso de la metodología de paquete de cuidados (care bundle)aplicada a la prevención de lesiones por presión adquiridas en hospital en pacientes adultos: revisión exploratoria / The care bundle approach applied to the prevention of hospital acquired pressure injuries in adults: a scoping review

Objetivo: Explorar el estado del conocimiento sobre la metodología del paquete de cuidados (PCuid) en la prevención de lesiones por presión adquiridas en hospital en pacientes adultos. Metodología: Revisión exploratoria en 10 bases de datos bibliográficos. Se incluyeron las publicaciones relacionadas con pacientes adultos ingresados en unidades de hospitalización convencional. Se realizó una descripción narrativa sin análisis de la calidad metodológica. Resultados: Se seleccionaron 31 artículos de diferentes diseños de investigación, identificando 9 PCuid. Como resultados cuantitativos, se obtuvieron reducciones de la incidencia de lesiones por presión desde el 8 al 90%, en la prevalencia del 37 al 94%, o incrementos en el número de días sin lesiones por presión desde el 50 al 59%. Otros efectos fueron un aumento del 36% en la utilización de la escala de Braden para la valoración del riego de lesiones por presión, o la mejora de cumplimentación de los registros de lesiones por presión del 13%. Desde el punto de vista cualitativo, los profesionales consideraron la aplicación de un PCuid como factible y aceptable, destacando como beneficios el aumento de la comunicación, los conocimientos y la participación en la prevención de LPP. Los pacientes consideraron la aplicación del PCuid como aceptable al aumentar su participación en el cuidado, favorecer la interacción con el personal y proporcionar información fácil de entender. Conclusión:La metodología del PCuid mejora la prevención de LPP en adultos hospitalizados. Son necesarios más estudios y de mayor calidad para valorar su efectividad. Resultaría recomendable estandarizar el uso de un único indicador de resultados que permitiera la comparación entre PCuid con distintos contenidos, preferiblemente la incidencia o la prevalencia de lesiones por presión adquiridas en el hospital (AU)

Objective: To explore the state of knowledge regarding the care bundle (CB) approach in the prevention of hospital-acquired pressure injuries (PI) in hospital wards in adult patients. Methodology: Scoping review from 10 bibliographic databases. Publications related to adult patients admitted to conventional hospital wards were included. A narrative description was made without analysis of methodological quality. Results:31 articles were selected with different designs, identifying 9 CB. As quantitative results, reductions in the incidence of PI were obtained from 8% to 90%, in the prevalence from 37% to 94%, or increases in the number of days without PI from 50% to 59%. Other effects were a 36% increase in the use of the Braden scale for the assessment of PI risk, or a 13% improvement in the completion of PI records. From a qualitative point of view, the professionals considered the application of a CB as feasible and acceptable, highlighting the increased communication, knowledge and participation in the prevention of PI as benefits. Patients considered the application of CB as acceptable by increasing their participation in care, promoting interaction with staff and providing easy to-understand information. Conclusion: The CB methodology improves the prevention of PI in hospitalized adults. More and higher quality studies are needed to assess its effectiveness. It would be advisable to standardize the use of a unique indicator of results that would allow comparison between CB with different contents, preferably the incidence or prevalence of PI hospital acquired (AU)

Prevalencia de las lesiones cutáneas relacionadas con la dependencia en adultos hospitalizados en España: resultados del 6º Estudio Nacional del GNEAUPP 2022 / Prevalence of dependencerelated skin lesions in hospitalised adult population in Spain: Results of the 6th GNEAUPP National Study 2022

Objetivos: Obtener indicadores epidemiológicos actualizados paralas lesiones cutáneas relacionadas con la dependencia en unidades dehospitalización de adultos de hospitales españoles, tanto globales comoajustados. Analizar las características demográficas y clínicas de laspersonas con lesiones cutáneas relacionadas con la dependencia, y de laslesiones. Metodología: Estudio observacional, transversal, tipo encuestaepidemiológica (6.º Estudio Nacional de Prevalencia), dirigido a todos loshospitales de España. Recogida de datos mediante formulario seguro online.Variables: características de los hospitales y de las unidades, pacientesingresados, pacientes con cada tipo de lesiones cutáneas relacionadascon la dependencia, clasificación de las lesiones. Se estimó la prevalenciacruda global y ajustada por hospitales y por tipo de unidades. Resultados:Participaron 470 unidades de hospitalización de adultos pertenecientesa 67 hospitales de todo el territorio nacional. La prevalencia global delesiones cutáneas relacionadas con la dependencia fue del 8,4%. Segúnel tipo de lesiones, las prevalencias fueron: lesiones por presión 7,7%;combinadas 0,9%; humedad 1,5%; por fricción 0,9%, y desgarros 0,8%.Los hospitales pequeños, de menos de 200 camas, son los que presentanprevalencias mayores. Las unidades con prevalencias más altas fueron:cuidados paliativos (24,2%), UCI (21,5%) y unidades posquirúrgicas y dereanimación (14,8%). La mayoría de las lesiones son de origen nosocomial(80%), producidas en el mismo o en otro hospital. Siguen faltando laimplementación de medidas preventivas en los centros y la dotación derecursos de prevención. Conclusiones: La prevalencia de lesiones cutáneasrelacionadas con la dependencia se mantiene en cifras similares a la deestudios anteriores en hospitales españoles, con gran variabilidad en función del tamaño del centro y las unidades en las que ingresa el paciente. (AU)

Objectives: To obtain updated epidemiological indicators fordependence-related skin lesions (DSRL) in adult inpatientunits of Spanish hospitals, both global and adjusted. Toanalyse the demographic and clinical characteristics of personswith DRSLs and lesions. Methodology: Observational,cross-sectional, epidemiological survey-type study (6thNational Prevalence Study), aimed at all hospitals in Spain.Data collection by means of a secure online form. Variables:characteristics of hospitals and units, patients admitted,patients with each type of DRSL, classification of lesions.Overall and adjusted crude prevalence was estimated byhospital and by type of unit. Results: A total of 470 adultinpatient units from 67 hospitals nationwide participated.The overall prevalence of DRSL was 8.4%. According totype of injury, the prevalences were: pressure injuries 7.7%;combined injuries 1.5%; moisture 1.4%; friction 0.9%; andtears 0.8%. Small hospitals with less than 200 beds haveshigher prevalence. The units with the highest prevalencewere: palliative care (24.2%), ICU (21.5%), and post-surgicaland resuscitation units (14.8%). Most of the injuries are ofnosocomial origin (80%), produced in this or other hospitals.The implementation of preventive measures in the centresand the provision of resources are still lacking. Conclusions:The prevalence of DRSL remains similar to that of previousstudies in Spanish hospitals, with great variability dependingon the size of the centre and the units to which the patient isadmitted. (AU)

Prevalencia de las lesiones cutáneas relacionadas con la dependencia en centros de atención primaria de salud de España: resultados del 6º Estudio Nacional del GNEAUPP 2022 / Prevalence of pressure injuries and other dependence-related skin lesions in primary healthcare centers in Spain: Results of the 6th GNEAUPP National Study 2022

Objetivos: Obtener indicadores epidemiológicos actualizados para laslesiones cutáneas relacionadas con la dependencia en centros de atenciónprimaria de salud españoles, tanto globales como ajustados. Analizarlas características demográficas y clínicas de las personas con lesionescutáneas relacionadas con la dependencia y de las lesiones. Metodología:Estudio observacional, transversal, tipo encuesta epidemiológica (6.ºEstudio Nacional de Prevalencia), dirigido a todos los centros deatención primaria de salud en España. Recogida de datos medianteformulario seguro online. Variables: características de los centros deatención primaria, población total, población mayor de 65 años ypoblación en programas de atención domiciliaria, pacientes con cadatipo de lesiones cutáneas relacionadas con la dependencia, clasificaciónde las lesiones. Se estimó la prevalencia cruda global poblacional yajustada en mayores de 65 años y en personas en programas de atencióndomiciliaria. Resultados: Se han obtenido datos de una población de1.754.228 personas atendidas en 131 centros de atención primaria desalud españoles. La prevalencia de lesiones cutáneas relacionadas conla dependencia en las personas en pacientes atendidos en programasde atención domiciliaria (ATDOM) fue del 5,82%. Solo un 7,7% delos centros declararon no tener ninguna persona con lesiones cutáneasrelacionadas con la dependencia atendida en el momento de obtenerlos datos. La prevalencia casi se duplica en los centros rurales (7,1%)y mixtos (6,0%) respecto a los centros urbanos (3,9%). Las lesiones seoriginaron en el mismo domicilio del paciente en un 79,8% de los casos,y solo un 18,7% se originaron durante el ingreso del paciente en unainstitución. (AU)

Objectives: To obtain updated epidemiological indicatorsfor dependence-related skin lesions (DRSL) in SpanishPrimary Health Care (PHC) centres, both global andadjusted. To analyse the demographic and clinicalcharacteristics of people with DRSL and lesions. and thelesions. Methodology: Observational, cross-sectional,epidemiological survey-type study (6th NationalPrevalence Study), aimed at all PHC centres in Spain. Datacollection by means of a secure on-line form. Variables:characteristics of primary care centres, total population,population over 65 years of age and population in homecare programmes, patients with each type of DRSL,classification of lesions. We estimated the overall crudeprevalence in the population and adjusted prevalence,in people over 65 years of age and in people in homecare programmes. Results: Data were obtained from apopulation of 1,754,228 people cared for in Spanish PHCcentres in 131 centres. The prevalence of DRSL in personsin patients attended in home care programmes (HCP) was5.82%. Only 7.7% of the centres reported not having anypersons with DRSL in care at the time of data collection.The prevalence almost doubles in rural (7.1%) and mixed(6.0%) centres compared to urban centres (3.9%). Injuriesoriginated in the patient’s own home in 79.8% of cases,and only 18.7% originated during the patient’s admissionto an institution. The profile is that of an 83-year-oldwoman with mixed incontinence and using a staticmattress surface. Conclusions: The prevalence of primary care DRSL in Spain remains similar to previous studies,with great variability depending on the location of thecentre. Four out of 5 lesions develop in the patient’shome. (AU)

Prevalencia de las lesiones cutáneas relacionadas con la dependencia en residencias de mayores y centros sociosanitarios de España: resultados del 6º Estudio Nacional del GNEAUPP 2022 / Prevalence of dependence-related skin lesions in nursing home in Spain: Results of the 6th GNEAUPP National Study 2022

Objetivos: Obtener las cifras de prevalencia de las lesiones cutáneasrelacionadas con la dependencia en centros residenciales para mayores ycentros sociosanitarios españoles. Analizar las características demográficasy clínicas de las personas con lesiones cutáneas relacionadas con ladependencia y de las lesiones. Metodología: Estudio observacional,transversal, tipo encuesta epidemiológica (6.º Estudio Nacional dePrevalencia), dirigido a todas las residencias y centros sociosanitariosde España. Recogida de datos mediante formulario seguro online.Variables: características de los hospitales y de las unidades, pacientesingresados, pacientes con cada tipo de lesiones cutáneas relacionadascon la dependencia, clasificación de las lesiones. Se estimó la prevalenciacruda global y ajustada por hospitales y por tipo de unidades. Resultados:Se han obtenido datos de 74 centros sociosanitarios y residencias demayores. Solo un 9,5% de los centros declararon no tener ningunapersona con lesiones cutáneas relacionadas con la dependencia atendidaen el momento de obtener los datos. La prevalencia global de lesionescutáneas relacionadas con la dependencia fue del 9,28% (IC95%,5,45-6,71), un 3% más que en el anterior. Las cifras de prevalencia decada tipo de lesión fueron: presión, 6,05%; humedad, 2,35%; fricción,1,35%; desgarros cutáneos, 2,38%, y combinadas, 0,61%. Esto suponeun incremento en todas las lesiones menos las combinadas. La prevalenciade todas las lesiones cutáneas relacionadas con la dependencia fue mayoren los centros públicos que en los concertados y privados. En un 85,2%,las lesiones cutáneas relacionadas con la dependencia eran de origennosocomial (originadas en la residencia u otra institución residencial)y solo un 10,9% se originaron en los domicilios. (AU)

Objectives: To obtain the prevalence figures ofdependence-related skin lesions (DRSL) in Spanish nursinghomes and long term care centres (NH-LTCC). To analysethe demographic and clinical characteristics of peoplewith DRSL and lesions. Methodology: Observational,cross-sectional, epidemiological survey-type study (6thNational Prevalence Study), aimed at all NHC-LTCC inSpain. Data collection by means of a secure on-line form.Variables: characteristics of hospitals and units, patientsadmitted, patients with each type of DRSL, classificationof lesions. Overall and adjusted crude prevalence wasestimated by hospital and by type of unit. Results: Datawere obtained from 74 NHC-LTCC. Only 9.5% of thecentres reported not having any person with DRSL in theircare at the time of data collection. The overall prevalenceof DRSL was 9.28% (95%IC, 5.45-6.71); 3% higher thanin the previous study. The prevalence figures for each typeof injury were: pressure 6.05%, moisture 2.35%, friction1.35%, skin tears 2.38%. combined 0.61%. Thisrepresents an increase in all but combined injuries. Theprevalence of all DRSLs was higher in the public centresthan in the state and private centres. The 85.2% ofthe DRSLs were of nosocomial origin (originating in anursing home or other residential institution) and only10.9% originated at home. Conclusions: The prevalenceof DRSL in nursing homes is among the highest in thistype of centre in the historical series of studies carriedout in Spain by the GNEAUPP. This higher prevalencecould be explained by the situation in which many havebeen left after the COVID pandemic and a relaxation in the prevention programmes implemented. (AU)

Nanostructural Characterization of Luminescent Polyvinyl Alcohol/Graphene Quantum Dots Nanocomposite Films.

This study focuses on the fabrication of polymer nanocomposite films using polyvinyl alcohol (PVA)/graphene quantum dots (GQDs). We investigate the relationship between the structural, thermal, and nanoscale morphological properties of these films and their photoluminescent response. Although according to X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), and differential thermal analysis (DTA), the incorporation of GQDs does not significantly affect the percentage crystallinity of the PVA matrix, for a range of added GQD concentrations, atomic force microscopy (AFM) showed the formation of islands with apparent crystalline morphology on the surface of the PVA/GQD films. This observation suggests that GQDs presumably act as nucleating agents for island growth. The incorporation of GQDs also led to the formation of characteristic surface pores with increased stiffness and frictional contrast, as indicated by ultrasonic force microscopy (UFM) and frictional force microscopy (FFM) data. The photoluminescence (PL) spectra of the films were found to depend both on the amount of GQDs incorporated and on the film morphology. For GQD loads >1.2%wt, a GQD-related band was observed at ~1650 cm-1 in FT-IR, along with an increase in the PL band at lower energy. For a load of ~2%wt GQDs, the surface morphology was characterized by extended cluster aggregates with lower stiffness and friction than the surrounding matrix, and the PL signal decreased.

Algorithm for the differential diagnosis between dependence-related skin injuries and severe life-threatening skin injuries.

AIM: To develop a diagnostic algorithm to differentiate dependence-related skin injuries (avoidable) from severe life-threatening skin injuries (unavoidable). METHOD: A nominal group technique was used. Six experts with extensive knowledge of these types of injuries were selected for the group. All were nurses with a PhD in wound research and had more than 15 years of experience in wound care. The experts were asked only one question: In your opinion, what are the basic and indispensable aspects to differentiate a dependence-related skin injury (DR-SI) from a severe life-threatening skin injury (SLT-SI)? RESULTS: The experts identified three basic elements to differentiate DL-SI and SLT-SI (clinical situation, provision of care, and clinical characteristics of the lesions). A diagnostic algorithm was developed to differentiate the two types of skin lesions using the three basic elements identified, a literature review, and what was published in the two articles that define DR-SI and STL-SI. CONCLUSION: We developed a diagnostic algorithm to differentiate dependence-related skin injuries (avoidable) from severe life-threatening skin injuries (unavoidable). The algorithm also facilitates the identification of the subtypes of these injuries, depending on its location and characteristics.

Bots' Activity on COVID-19 Pro and Anti-Vaccination Networks: Analysis of Spanish-Written Messages on Twitter.

This study aims to analyze the role of bots in the dissemination of health information, both in favor of and opposing vaccination against COVID-19. Study design: An observational, retrospective, time-limited study was proposed, in which activity on the social network Twitter was analyzed. Methods: Data related to pro-vaccination and anti-vaccination networks were compiled from 24 December 2020 to 30 April 2021 and analyzed using the software NodeXL and Botometer. The analyzed tweets were written in Spanish, including keywords that allow identifying the message and focusing on bots' activity and their influence on both networks. Results: In the pro-vaccination network, 404 bots were found (14.31% of the total number of users), located mainly in Chile (37.87%) and Spain (14.36%). The anti-vaccination network bots represented 16.19% of the total users and were mainly located in Spain (8.09%) and Argentina (6.25%). The pro-vaccination bots generated greater impact than bots in the anti-vaccination network (p < 0.000). With respect to the bots' influence, the pro-vaccination network did have a significant influence compared to the activity of human users (p < 0.000). Conclusions: This study provides information on bots' activity in pro- and anti-vaccination networks in Spanish, within the context of the COVID-19 pandemic on Twitter. It is found that bots in the pro-vaccination network influence the dissemination of the pro-vaccination message, as opposed to those in the anti-vaccination network. We consider that this information could provide guidance on how to enhance the dissemination of public health campaigns, but also to combat the spread of health misinformation on social media.

Drone Applications for Emergency and Urgent Care: A Systematic Review.

INTRODUCTION: In recent years, the use of drones in health emergencies has increased. Among their main benefits are avoiding endangering rescuers, travelling long distances in a short time, or contacting victims in risky situations; but despite their multiple advantages, their use has not been fully demonstrated. STUDY OBJECTIVE: This study aims to identify the available evidence on the use of drones in emergency health care compared to traditional health care. METHODS: Systematic review of the literature was conducted. Search protocols were developed to locate studies that met the established selection criteria. Six experimental or quasi-experimental studies with high methodological quality published from the beginning of indexing until 2020 were included. RESULTS: Drones covered a significantly larger area than other traditional tracking methods and were very useful for performing preliminary triage, determining needs, and knowing the scene prior to the arrival of rescuers. In addition, drones reduced the time required to locate the victim. CONCLUSIONS: Drones are an element to be taken into account when attending health emergencies as they significantly improve the distance travelled to locate accident victims, have the possibility of performing triage prior to the arrival of the health care units, and improve the time and quality of the care provided.

Undergraduate nursing students' knowledge of Alzheimer's disease and related dementias care.

BACKGROUND: The increase in the number of people with Alzheimer's disease and Related Dementias (ADRD) will results in an increased need for nurses with up-to-date knowledge of ADRD and who are well-educated in ADRD care. Therefore, it is important to be sure that this topic is covered in the undergraduate nursing curriculum. PURPOSE: To assess undergraduate nursing students' knowledge of Alzheimer's disease and related dementias care. METHOD: Cross-sectional study carried out among nursing students at two universities in southern Spain. The University of Jaen (UJA)-Alzheimer's Care scale was used to measure their knowledge. RESULTS: The mean age of the students was 21.39 years, and 83.2% of the 678 students were women. For students, the UJA-Alzheimer's Care scale has a good fit and reliability of 0.99 for the items and 0.74 for the persons, according to the Rasch model. The mean knowledge score of nursing students was 15.33 (SD 3.69) out of 23; (95%CI: 15.06-15.61). The value of the latent variable (theta) was 1.16 (SD 1.21); (95%CI: 1.06-1.25). The factors positively associated with students' knowledge were the number of years in the program, experience in caring for a patient with ADRD during their placements, and the education on ADRD received in the nursing program as self-rated by the students. CONCLUSION: The UJA-Alzheimer's Care scale is a useful tool for measuring knowledge of ADRD care among nursing students in Spain and other Spanish-speaking countries. Nursing students at the two universities reached moderate scores in the knowledge of ADRD care. More years in the nursing program, practical experience in clinical placements, and higher self-rated level of education on ADRD received during the program were associated with higher scores on knowledge.

Health Literacy and Critical Lecture as Key Elements to Detect and Reply to Nutrition Misinformation on Social Media: Analysis between Spanish Healthcare Professionals.

Health misinformation about nutrition and other health aspects on social media is a current public health concern. Healthcare professionals play an essential role in efforts to detect and correct it. The present study focuses on analyzing the use of competencies associated with training in methodology, health literacy, and critical lecture in order to detect sources of health misinformation that use scientific articles to support their false information. A qualitative study was conducted between 15 and 30 January 2022, wherein the participants were recruited from active users from a nutrition conversation on Twitter, diets, and cancer and defined themselves as healthcare professionals. This study demonstrates that health literacy and critical lecture competencies allow for the detection of more misinformation messages and are associated with a high rate of responses to users that spread the misinformation messages. Finally, this study proposes the necessity of developing actions to improve health literacy and critical lecture competencies between healthcare professionals. However, in order to achieve this, health authorities must develop strategies to psychologically support those healthcare professionals faced with bullying as a result of their activity on social media debunking health hoaxes.

Skin injuries associated with severe life-threatening situations: A new conceptual framework.

PURPOSE: To create a conceptual framework for skin injuries developing in patients whose lives are severely compromised or who are expected to die within a short period of time. To name and classify these types of skin injuries. To describe the clinical features of the different types of skin injuries that may occur in terminally ill and/or dying patients. DESIGN: A sequential design with several different phases (a literature review, a nominal group, and a consensus conference) was used. METHODS: Six experts with extensive knowledge of these types of injuries were selected for the nominal group. The traditional eight-phase nominal group technique was followed. The consensus conference consisted of participants voting on different options based on the statements elaborated with the expert panel summarizing the best scientific evidence available. FINDINGS: Using all these elements, a conceptual framework was constructed to identify skin injuries associated with severe life-threatening situations (SI-SLTSs), defined as unpredictable and therefore unpreventable injuries indicating a serious threat to life or even imminent death. These injuries can occur in two forms: (a) as skin injuries associated with multiple organ dysfunction syndrome (SI-MODSs) or (b) as skin injuries associated with severe vasoconstriction (SI-ESVs). SI-MODSs develop very quickly and suddenly. They progress from superficial to deep stages abruptly, even within hours. The severity of the injuries does not reflect the care provided to the patient. Individuals suffering from these injuries have an irreversible clinical condition. SI-ESVs also appear in individuals who are in a very critical, even terminal, clinical condition. They are frequently treated in the ICU and may exhibit severe vasoconstriction due to their disease process (e.g., shock), sometimes exacerbated by vasoconstriction caused by various drugs (e.g., noradrenaline). CONCLUSIONS: We have developed a conceptual framework for skin injuries developing in patients whose lives are severely compromised or who are expected to die within a short period of time and have named them SI-SLTSs, distinguishing between SI-MODSs and SI-ESVs. CLINICAL RELEVANCE: This new conceptual framework may help clinicians understand the mechanisms and the pathophysiology of skin injuries that develop in terminally ill and/or dying patients associated with multi-organ failure. Through this new framework these injuries can be identified and differentiated from pressure injuries or other dependence-related skin lesions.

Nurses and ward managers' perceptions of leadership in the evidence-based practice: A qualitative study.

AIM: To describe nurses and ward managers' experiences with nursing leadership in the implementation of evidence-based practice. BACKGROUND: The implementation of evidence-based practice requires to identify the most suitable styles of nursing leadership for the successful application. DESIGN: A qualitative descriptive study. METHODS: The study was carried out with 57 nurses (clinical nurses and ward managers) in eight focus groups from five public hospitals. Template analysis, using the Promoting Action on Research Implementation in Health Services framework, was used. The Consolidated Criteria for Reporting Qualitative Research guide was followed in planning and reporting this research. RESULTS: Three types of nursing leadership were identified: traditional leadership, medium leadership and transformational leadership. Traditional leadership was the most frequent, with a predominance of bureaucratic tasks for ward managers, so implementation of evidence-based practice is difficult. CONCLUSION: Nurses do not feel empowered and they perceive the changes as an imposition. In the absence of strong leadership for evidence-based practice, a natural leader emerges. IMPLICATIONS FOR NURSING MANAGEMENT: Clinical nurses demand more empowerment for decision-making, and ward managers need clarity of roles. To create an environment favourable to evidence-based practice, it is necessary consider the role of the transformational leader.