1.
Eur J Med Chem
; 78: 419-24, 2014 May 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24704614
RESUMO
A novel series of pyrrolothiazines 2-4 and pyrrolopyrimidines 5-7 have been synthesized. The structures of these compounds were established by spectroscopic and element microanalytical data. The newly synthesized compounds were evaluated as inhibitors of TSG-14. The most effective results were obtained by the S-sec-butyl derivatives 6e (80%) and the N-ethyl derivatives 4e (70%).