Balloon kyphoplasty in the treatment of osteoporotic vertebral compression fracture nonunion.

Patients with nonunion of osteoporotic vertebral compression fractures that are refractory to conservative treatments have persistent back pain, progressive vertebral body collapse and kyphosis, and mobility of the fracture. Although many previous reports have reported vertebral compression fractures treated by balloon kyphoplasty, few data is available on using this method to treat nonunion of vertebral compression fractures. This study evaluated the therapeutic potential of balloon kyphoplasty in the treatment of nonunion of osteoporotic vertebral compression fractures. Twenty-one patients with nonunion of osteoporotic vertebral compression fractures were treated with balloon kyphoplasty. The criteria for diagnosis of nonunion osteoporotic vertebral compression fractures included the following: (1) history of pain for at least 6 months at the fracture site; (2) low T1- and high T2-signal on magnetic resonance images; (3) widening of fracture line on routine radiographs; and (4) movement of the endplate and changes of anterior vertebral heights on hyperextension radiographs. All patients were followed for 9 to 33 months postoperatively (mean 25 months). Statistically significant improvements in the mean postoperative anterior and middle vertebral body heights were observed compared with preoperative values. There was also statistically significant improvement in the mean values for Cobb's angle, pain (visual analog scale), and the Oswestry Disability Index at the postoperative assessment compared with the preoperative assessment. No statistically significant differences were noted between the postoperative and final follow-up assessment in any of the evaluated efficacy measures. The study suggests that balloon kyphoplasty is an effective technique to treat nonunion of osteoporotic vertebral compression fractures.

An evaluation of halo pin insertion torque on outer table penetration in elderly patients.

STUDY DESIGN: An experimental anatomic study performed on elderly cadaveric skulls. OBJECTIVES: (1) To determine the pin penetration depths in outer table of skull at different torques in the elderly population during halo pin insertion and (2) to validate a safe range of torque for use in this population. SUMMARY OF BACKGROUND DATA: The elderly are at an increased risk of falls, which can lead to cervical fractures. The halo pins used to stabilize these injuries present unique problems in this population owing to osteoporosis, and intracranial pin penetration should always be avoided. METHODS: A halo ring was used to insert pins in 4 standard positions on 10 elderly cadaveric skulls. Incremental torques were used to drive the pin into the outer table, and the penetration of each pin was measured using computed tomography imaging at each stage. RESULTS: Eight to Twelve in-lb of torque was not sufficient to fully penetrate the outer table of the skull. Only at 16 in-lb of torque was the outer table penetrated, and only anterolaterally, hence the posterolateral outer table is more resistant to penetration than the anterolateral outer table. CONCLUSIONS: Despite age-related bone changes in the elderly, it is still safe to use 8 in-lb of torque when inserting pins for a halo vest. However, as the anterolateral outer table is weaker than the posterolateral outer table, a new pin design with broader shoulders should be used anterolaterally to ensure maximal patient safety.

Implantable diagnostic monitoring devices for evaluation of syncope, and tachy- and brady-arrhythmias.

Symptoms arising from cardiac arrhythmias are often transient. Consequently, defining the responsible rhythm disturbance remains a challenge. However, absent a confident diagnosis of the arrhythmic basis for the symptoms, it is not possible to develop an effective treatment strategy. The implantable loop recorder (ILR) has become a valuable element in the evaluation of patients with suspected intermittent arrhythmia related symptoms. In this regard, clinical studies have not only demonstrated its superior effectiveness compared to other monitoring modalities, but even suggest that it may be cost-effective for the ILR to be used at an earlier stage of the evaluation strategy.

Comparison of automatic and patient-activated arrhythmia recordings by implantable loop recorders in the evaluation of syncope.

The implantable loop recorder (ILR) has become an important tool for evaluating patients with recurrent syncope. Second generation ILRs have the ability to record events either automatically (auto activated) or by manual activation (patient activated). In an attempt to evaluate the relative utility of the auto-activation feature, this study stratified ILR events based on a grading system designed to classify detected arrhythmias in terms of the likelihood that they provide a diagnostic basis for syncope. Data from 50 patients (27 men, mean age 64 +/- 22 years) who underwent ILR implantation for investigation of recurrent syncope were assessed. The arrhythmia syncope grading system used 5 levels, ranging from grade 0 (rhythm recorded during syncope) to grade IV (rhythm unlikely to provide a diagnostic basis for syncope). Thirty-six patients (72%) demonstrated > or =1 auto-activated or patient-activated recording during a follow-up of 14.3 +/- 7.9 months. Of the total of 529 recordings, 223 (194 after auto activation [86.9%]) from 30 patients showed a rhythm abnormality. Auto activation was more effective for documenting arrhythmias that were recorded during syncope or those with highest probability of providing a syncope diagnosis (grade 0 or I arrhythmias: auto activated, 19 patients, patient activated, 3 patients). Times from ILR implantation to first grade 0 and grade I arrhythmias were 13.4 and 7.8 months, respectively. The ILR auto-activation feature proved effective in providing a high probability basis for syncope (196 arrhythmia recordings [87.1%] in 27 patients) and enhanced the diagnostic effectiveness of the device compared with patient activation alone (29 arrhythmia recordings [12.9%] in 6 patients).