Biosimilarity: resemble or not? The diffirence between biosimilarity and low molecule medicine

Studies of 11 biosimilarities. Result: in vitro bioactive was from 71-226% compared to Eprex. 9/11 biosilmilars had different isome from standard. Among 12 samples from 5 producers, the effectiveness was from 67.6% to 119.4% differently from European stardard. In three samples, toxic level was 15 higher than maximum accepted starndard. Isomeric samples also varied among producers. The study showed Epoetin produced outside of The United States and Europe had very different elements not in conformity with full process. The content on label was often lower or exceeded the limit.

Updates on the use of vardenafil (Levitra) in the treatment of erection disorders

Updates on the use of vardenafil (Levitra) in the treatment of erection disorders including: specific inhibition with PDE5, treatment efficacy, pharmacokinetics, tolerance level, interaction, contraindication, cautions especially for people with cardiovascular diseases or penis surgery deformation, dosage and use. Except for above contraindication and cautions, vardenafil can be considered as first choice for men with erection disorders in accordance with PDE5 inhibition treatment

C-reactive protein (CRP) assay to evaluate the inflammation

Some protein, at acute phase were usually used to diagnose and to monitor the status of inflammation in infection diseases. In healthy person, CRP exists only in the form of patch, but CRP is as an sensitive indicator of a reaction of systemic inflammation, in turn, inflammation had a key role in physiopathology of arteriosclerosis. Person with high content of CRP will have a 4.5 fold risk of heart attack in comparing with healthy one. Moreover it has diverse manifestations in other severe diseases such as blood sugar disorders, dental gingival diseases, smoking, overweight and obese

Red wine and the "French paradox"

Red wine contains much active substances of super antioxydant with great value of preventing and treating diseases. In vitro and in vivo researches on inimal, epidemiological investigations conducted on human hah demonstrated a bright future on the prevention and treatment of atherosclerosis, cancer, viral diseases and mental declining, Alzheimer disease… Moderate use daily of red wine offers considerable advantage for health and prolongs the longevity. However, because of the containing of alcohol, it must weigh the pros and cons in using red wine.