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1.
Sci Adv ; 6(22): eaay4945, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32518819

RESUMO

Atmospheric new-particle formation (NPF) affects climate by contributing to a large fraction of the cloud condensation nuclei (CCN). Highly oxygenated organic molecules (HOMs) drive the early particle growth and therefore substantially influence the survival of newly formed particles to CCN. Nitrogen oxide (NOx) is known to suppress the NPF driven by HOMs, but the underlying mechanism remains largely unclear. Here, we examine the response of particle growth to the changes of HOM formation caused by NOx. We show that NOx suppresses particle growth in general, but the suppression is rather nonuniform and size dependent, which can be quantitatively explained by the shifted HOM volatility after adding NOx. By illustrating how NOx affects the early growth of new particles, a critical step of CCN formation, our results help provide a refined assessment of the potential climatic effects caused by the diverse changes of NOx level in forest regions around the globe.

2.
Unfallchirurg ; 114(8): 663-70, 2011 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-21800137

RESUMO

The incidence of pelvic fractures at 0.3-8% is low compared to all fractures. Nevertheless, the number of pelvic fractures in the elderly is increasing. Due to the increased age of the patient differences in trauma mechanism, fracture pattern and therapy occur. Most pelvic fractures in the elderly are caused by low-energy trauma. This makes it difficult to find the right diagnosis especially in insufficiency fracture of the pelvis. The time until the right treatment is started is prolonged significantly. Elderly patients who suffer from a high-energy fracture have a significantly higher risk of haemorrhage. At the same time emergency stabilisation of the pelvis using a C-clamp is dangerous due to the special fracture morphology with transiliac instabilities and the combination with osteoporosis. Low-energy trauma leads to simple fractures of the pubis, which often can be treated without operation. In these cases fractures of the dorsal pelvic ring need to be excluded using CT scan. Fracture of the dorsal part of the pelvic ring such as insufficiency fractures of the sacrum should be stabilized by 3D-guided percutaneous iliosacral screw fixation to reduce pain and allow early mobilisation.


Assuntos
Fraturas por Osteoporose/epidemiologia , Fraturas por Osteoporose/cirurgia , Ossos Pélvicos/lesões , Acidentes por Quedas/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Parafusos Ósseos , Estudos Transversais , Diagnóstico Diferencial , Deambulação Precoce , Emergências , Feminino , Fixação Interna de Fraturas/métodos , Alemanha , Humanos , Processamento de Imagem Assistida por Computador , Imageamento Tridimensional , Masculino , Fraturas por Osteoporose/diagnóstico por imagem , Ressuscitação , Sacro/diagnóstico por imagem , Sacro/lesões , Sacro/cirurgia , Fatores Sexuais , Fraturas da Coluna Vertebral/diagnóstico por imagem , Fraturas da Coluna Vertebral/epidemiologia , Fraturas da Coluna Vertebral/cirurgia , Cirurgia Assistida por Computador , Tomografia Computadorizada por Raios X
3.
Unfallchirurg ; 112(1): 15-22, 2009 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-19096820

RESUMO

BACKGROUND: It is hypothesized that misplacement of sustentacular screws during osteosynthesis of intraarticular calcaneal fractures can be reduced with the help of navigation. A method for three-dimensional (3D) navigated placement of sustentacular screws for treating intraarticular calcaneal fractures is presented and evaluated. MATERIAL AND METHODS: 11 consecutive patients with 15 intraarticular calcaneal fractures were treated using 3D navigation. In 12 cases osteosynthesis was done through an extended lateral approach; in three cases, it was achieved through a minimally invasive percutaneous approach. For verification and documentation of the placed screws, a second 3D scan was performed. RESULTS: A total of 20 screws were placed using 3D navigation. None of the navigated screws was misplaced. Extra operating time due to navigation averaged 11.9 minutes (+/-2.2 min). CONCLUSION: Through a combination of intraoperative 3D imaging and navigation, placement of sustentacular screws is possible and can yield precise and reliable results. Especially in minimally invasive treatment, a high quality of osteosynthesis can be achieved.


Assuntos
Calcâneo/lesões , Calcâneo/cirurgia , Traumatismos do Pé/cirurgia , Fixação Interna de Fraturas/instrumentação , Fraturas Ósseas/cirurgia , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Cirurgia Assistida por Computador/instrumentação , Adulto , Idoso , Calcâneo/patologia , Desenho de Equipamento , Feminino , Traumatismos do Pé/patologia , Fixação Interna de Fraturas/métodos , Fraturas Ósseas/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Cirurgia Assistida por Computador/métodos , Adulto Jovem
4.
Unfallchirurg ; 112(1): 76-80, 2009 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-19096821

RESUMO

Persistent dysphagia after ventral instrumentation of a patient with a cervical spine fracture and diffuse idiopathic skeletal hyperostosis (DISH, or Forestier's disease) is a rare but dramatic complication. In this case report some pathogenetic factors are discussed. Accurate resection of the spondylophytes should be considered to avoid a ventral protrusion of the plate.


Assuntos
Vértebras Cervicais/lesões , Vértebras Cervicais/cirurgia , Transtornos de Deglutição/etiologia , Hiperostose Esquelética Difusa Idiopática/complicações , Fraturas da Coluna Vertebral/cirurgia , Fusão Vertebral/efeitos adversos , Paralisia das Pregas Vocais/etiologia , Idoso , Doença Crônica , Transtornos de Deglutição/diagnóstico , Diagnóstico Diferencial , Humanos , Masculino , Paralisia das Pregas Vocais/diagnóstico
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