RESUMO
Cutaneous diseases of the ear encompass a wide range of symptoms, complaints, and factors that negatively impact patients' well-being. These observations are frequently encountered by otolaryngologists and other physicians who treat individuals with ear-related issues. In this document, we aim to offer up-to-date information on diagnosing, predicting outcomes, and treating commonly occurring ear diseases.
Assuntos
Otopatias , Orelha Externa , Humanos , Otopatias/diagnóstico , Otopatias/terapiaAssuntos
Alopecia/diagnóstico por imagem , Alopecia/patologia , Dermoscopia , Dermatoses do Couro Cabeludo/diagnóstico por imagem , Couro Cabeludo/diagnóstico por imagem , Couro Cabeludo/patologia , Adulto , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Dermatoses do Couro Cabeludo/patologiaRESUMO
Skin cancers are relatively rare in patients with skin of color; however, they are an important public health concern because of disparities in patient outcomes. Gaps in skin cancer knowledge exist because of lack of large-scale studies involving people of color, and limitations in data collection methods and skin classification paradigms. Additional research is needed to address questions regarding risk and reasons for disparate skin cancer outcomes in these patients. We summarize the clinical and epidemiologic features for basal cell carcinoma, squamous cell carcinoma, and melanoma and touch on some of their unique features in patients with skin of color.
Assuntos
Asiático , Negro ou Afro-Americano , Carcinoma Basocelular/etnologia , Carcinoma de Células Escamosas/etnologia , Hispânico ou Latino , Melanoma/etnologia , Neoplasias Cutâneas/etnologia , Pigmentação da Pele , Carcinoma Basocelular/diagnóstico , Carcinoma Basocelular/patologia , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/patologia , Erros de Diagnóstico , Detecção Precoce de Câncer , Disparidades em Assistência à Saúde/etnologia , Humanos , Melanoma/diagnóstico , Melanoma/patologia , Infecções por Papillomavirus/epidemiologia , Fatores de Risco , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologiaRESUMO
PURPOSE:: Topical corticosteroids (TS) are a treatment for atopic dermatitis (AD) and psoriasis (Ps). We assessed whether use of a TS under conditions designed to enhance adherence would be effective in patients who "failed" TS in the outpatient setting. METHODS:: Individuals with treatment-resistant Ps or AD were recruited (AD, n = 12; Ps, n = 12). Six participants were randomized to each of 2 groups of desoximetasone 0.25% spray alone (n = 6) or desoximetasone spray plus twice-daily phone call reminders to use the medication. Disease severity was assessed. RESULTS:: In treatment-resistant Ps patients, desoximetasone spray, with reminders, resulted in statistically significant improvement in all outcome measures. In treatment-resistant AD patients, there was statistically significant improvement in some assessments. Despite the very small sample size and short evaluation time, statistically significant changes were detected in this cohort. This is evidence of the large effect size of TS for Ps and AD when the treatment is used. CONCLUSIONS:: Patients with "treatment-resistant" Ps and AD generally responded well to the use of desoximetasone spray in the trial setting. This may be due to better adherence in the study environment or patients' preference for the spray vehicle. Patient reminders contributed to improved clinical outcomes in Ps and AD patients with "treatment-resistant" disease.
