RESUMO
Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the eccrine duct leads to miliaria. The excretion of drugs into eccrine sweat may be a contributory factor in neutrophilic eccrine hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of eccrine gland pathophysiology.
Assuntos
Adulto , Criança , Humanos , Coma/induzido quimicamente , Doenças das Glândulas Sudoríparas/etiologia , Doenças das Glândulas Sudoríparas/fisiopatologia , Doenças das Glândulas Sudoríparas/induzido quimicamente , Eletrólitos/análise , Eritema Multiforme/induzido quimicamente , Fibrose Cística/metabolismo , Glândulas Écrinas/fisiopatologia , Glândulas Écrinas/metabolismo , Glândulas Écrinas/patologia , Hidradenite/induzido quimicamente , Hiperidrose/etiologia , Hiperidrose/fisiopatologia , Hipo-Hidrose/etiologia , Hipo-Hidrose/fisiopatologia , Metaplasia , Miliária/etiologia , Miliária/fisiopatologia , Suor/metabolismo , Suor/química , Suscetibilidade a Doenças , Tratamento Farmacológico/efeitos adversos , Vesícula/induzido quimicamenteRESUMO
Lymphomatoid papulosis is a chronic disease of cutaneous lymphoid infiltration characterized clinically by involuting and recurring papules, plaques, and nodules. The intriguing combination of a usually benign clinical course, a cytologically malignant lymphoid infiltrate on histologic examination, and a clear, but sporadic association with extracutaneous lymphomas has stimulated significant investigation. Application of recent technical advances to research in lymphomatoid papulosis prompts this review.