[Eosinophilic cystitis: review and two case reports]. / Cistitis eosinofílica: revisión y reporte de dos casos.

Eosinophilic cystitis is a low frequency disease, with less than 200 reported cases in the world. It is characterized by a bladder wall inflammation, mainly by eosinophils, with fibrosis and muscle necrosis areas. Its origin seems to be immunological, although the triggers are not well known. Several predispose factor have been described such as allergic diseases, bladder injuries, drugs, infections, etc. It affects patient of all ages, mainly adults. It presents with frecuency, haematuria and suprapubic pain. Other less frequent symptoms are disuria, urinary retention, nicturia, and enuresis. The laboratory study (urinalysis, urinalysis and haemogram) and radiology (ultrasound, intravenous pyelography, computed tomography and nuclear magnetic resonance) are non specific. The lesions observed in the cystoscopy could emulate other diseases, that why the proper diagnostic is the histological analysis. The management could be observation o antihistaminic, anti-inflammatory and corticoid treatment. In refractory cases, surgery is an alternative. In this work, two male adult cases are reported with their symptoms, studies and management.

Cistitis eosinofílica: Revisión y reporte de dos casos / Eosinophilic cystitis: Review and two cases report

La cistitis eosinofílica es una enfermedad de baja frecuencia, con menos de 200 casos reportados en el mundo. Se caracteriza por la inflamación de toda la pared vesical, predominantemente por eosinófilos, con fibrosis y áreas de necrosis muscular. Su origen parece ser inmunológico aunque los desencadenantes no se conocen bien. Se han descrito varios factores predisponentes como enfermedades alérgicas, trauma vesical, fármacos, infecciones, etc. Afecta a pacientes de todas las edades, preferentemente adultos. Se presenta con polaquiuria, hematuria y dolor suprapúbico. Otros de menor frecuencia son disuria, retención urinaria, nicturia y enuresis. El estudio de laboratorio (sedimento de orina, urocultivo, hemograma)y radiológico (ecotomografía, pielografía de eliminación, tomografía computada y resonancia nuclear magnética) son inespecíficos. En la cistoscopía se observan lesiones que pueden simular otras enfermedades, por lo que el diagnóstico definitivo es histológico. El manejo puede ser expectante o con antihistamínicos, antiinflamatorios y corticoides. En los casos refractarios al tratamiento médico la cirugía puede ser una alternativa. Reportamos dos casos de pacientes hombres, adultos, con su cuadro de presentación, estudio y manejo (AU)

Eosinophilic cystitis is a low frequency disease, with less than 200 reported cases in the world. It is characterized by a bladder wall inflammation, mainly by eosinophils, with fibrosis and muscle necrosis areas. Its origin seems to be immunological, although the triggers are not well known. Several predispose factor have been described such as allergic diseases, bladder injuries, drugs, infections, etc. It affects patient of all ages, mainly adults. It presents with frecuency, haematuria and suprapubic pain. Other less frequent symptoms are disuria, urinary retention, nicturia, and enuresis. The laboratory study(urinalysis, urinalysis and haemogram) and radiology (ultrasound, intravenous pyelography, computed tomography and nuclear magnetic resonance) are non specific. The lesions observed in the cystoscopy could emulate other diseases, that why the proper diagnostic is the histological analysis. The management could be observation o antihistaminic, anti-inflammatory and corticoid treatment. In refractory cases, surgery is an alternative. In this work, two male adult cases are reported with their symptoms, studies and management (AU)

[Intrauterine device migration to the bladder: four case reports]. / Migración de dispositivo intrauterino a vejiga: aportación de cuatro casos.

The intrauterine device has been commonly used in our population for many years as contraceptive method. One of the complications is the device migration out of the uterus. One of the most uncommon fait of this migration is the bladder, with few reports on the literature. In this work, four cases are reported with their clinical presentation, study and treatment.

Migración de dispositivo intrauterino a vejiga: aportación de cuatro casos / Intrauterine device migration to the bladder: four cases report

El dispositivo intrauterino (DIU) ha sido utilizado en nuestro medio durante muchos años como método anticonceptivo. Una de las complicaciones es la migración fuera del útero, siendo la localización vesical inusual, con escasos casos en la literatura. Presentamos cuatro casos de migración del DIU a la vejiga. Se describe cuadro clínico, estudio y tratamiento (AU)

The intrauterine device has been commonly used in our population for many years as contraceptive method. One of the complications is the device migration out of the uterus. One of the most uncommon fait of this migrationis the bladder, with few reports on the literature. In this work, four cases are reported with their clinical presentation, study and treatment (AU)

Radioterapia primaria en cancer prostático: 1993-2006 / Primary radiotherapy in prostatic cancer: 1993-2006

De 89 pacientes irradiados por Cáncer Prostático entre 1993 y 2004, con 2 años de seguimiento mínimo, se analiza indicación, tipo de radioterapia y respuesta. El 56 por ciento fueron tratados por edad mayor a 70 años, 31 por ciento por patologías asociadas, y 8 por ciento por etapa T3 clínico. Obtuvimos 29 por ciento de remisión completa (PSAnadir <0,5 ng/ml); 69,6 por ciento remisión parcial y 1,4 por ciento sin respuesta. 58 por ciento de recurrencia, mayor en el grupo con respuesta parcial (66,6 por ciento), que en el grupo con respuesta completa (36 por ciento). La sobrevida libre de enfermedad es de 85 por ciento, 52,1, por ciento 43,4 por ciento , 42 por ciento, a los 12, 36, 60 y 84 meses respectivamente. La sobrevida específica es de 79 por ciento, 63 por ciento y 38 por ciento a los 4, 6 y 12 años respectivamente.

Of 89 patients irradiated for prostate cancer between 1993 and 2004, with 2 years of follow-up, we analyzed the treatment, type of radiotherapy and results. 56 percent of patients were treated by age greater than 70 years, 31percent for associated diseases, and 8 percent for T3 clinical stage. 29 percent of patients entered into complete remission(PSA nadir 0.5 ng / ml), 69.6 percent partial remission and 1.4 percent showed no response. 58 percent of patients with recurrent symptoms was higher in the group with a partial recovery (66.6 percent), than in the group with acomplete recovery (36 percent). Disease free survival was 85, percent 52.1, percent 43.4 percent, 42 percent to 12, 36, 60 and 84months respectively. The specific survival was 79 percent , 63 percent and 38 percent at 4, 6 and 12 years respectively.

Tremor in Parkinson's disease: 24-hr monitoring with calibrated accelerometry.

Monitoring systems enable the long-term registration of tremor in patients with Parkinson's disease This method is useful in the objective measurement of tremor during the course of treatments. Indeed, the symptoms of tremor as well as the aggravating and attenuating influences can be observed under real-life conditions. The methodology of data recording and analysis, described in previous investigations, was extended to automatically detect body position and certain movement patterns with calibrated 4-channel accelerometry. The main purpose of the present investigation was to apply this refined and extended methodology to patients in a clinical rehabilitation program, and to examine its practability with respect to the results of the treatment and the patients' compliance. The methodology was tested on 30 patients (17 male, 13 female) with Parkinson's disease. The mean age was 64.8 years (s = 8.9). The Hoehn-Yahr index ranged from 1 to 3 (m = 2.3, s = 0.7) and the overall UPDRS scale between 10 and 74 (m = 42.9, s = 18.1). The data recording included: (1) the registration of tremor under standardised conditions of rest and postural tremor test with and without distraction; (2) a standard protocol to obtain reference values for body position and movement; and (3) the 24-hr monitoring. 21 patients could be recorded a second time, on average 18 days after the first recording. Between the two registrations, patients received individually tailored drug treatment supplemented with specific activating physiotherapy, ergotherapy measures, and individual psychotherapeutic counseling. Changes between first and second recording were evident for the three tremor variables, but significant only for the 24-hr ambulatory monitoring. The between and within-subjects correlations of the tremor variables were rather low except the correlations between occurrence and amplitude (between-subjects. 87; within-subjects. 67). Conditions of rest and postural tremor test showed a correlation with corresponding segments of the ambulatory monitoring of about. 50 for the tremor occurrence. The best prediction of the day-time monitoring was made by the tremor tests with distraction, whereas the night segment was best predicted by the standard protocol.

[Complications in administration of contrast media in the catheterization laboratory: a 5-year retrospective study]. / Komplikace podání kontrastních látek v katetrizacní laboratori: petiletá retrospektivní studie.

UNLABELLED: Iodine contrast substances (CS) are used since the twenties of the 20th century. From the chemical aspect benzoic acid derivatives are involved which are classified according to their osmolality (high-low- and isoosmolar) tendency of ionization (ionic and non-ionic) and according to the molecular structure monomers and dimers). Side-effects are due to their osmotic, ionic and chemical action on tissues. They include a number of systemic and organ symptoms (cardiovascular, immunological, haemocoagulation, neurological and renal), from the clinical aspect divided into mild, medium severe and severe. The relatively high incidence of undesirable reactions when ionic high-molecular CS are used led to the-development of non-ionic preparations with a lower osmolality, the more extensive use of which is limited by economic factors. Moreover so far convincing clinical data are lacking that the higher incidence of undesirable reactions after the use of CS has a clinical impact. OBJECTIVE: To summarize experience with administration of CS in the catheterization laboratory of the Cardiocentre of the General Faculty Hospital during diagnostic and intervention procedures within 5 years with regard to the occurrence of undesirable effects when comparing ionic and non-ionic CS. METHOD: Retrospective analysis of a group of patients examined in the catheterization laboratory to whom a CS was administered during the period between Jan. 1 1995 and Dec. 31 1999. RESULTS: In 1995-1999 (5 years) in the catheterization laboratory a total of 10,149 procedures where implemented where ionic (ioxitalam-Telebrix 350) and non-ionic (iopromide Ultravist 370, ioversol--Optiray 370 and iomeprol-Iomeron 350) contrast substances were administered. Ionic CS were administered in 4,668 (46%) and non-ionic CS in 5,481 (54%) instances. Undesirable effects were recorded in a total of 107 (1.1%) patients, incl. ventricular fibrillation in 76 (0.75%), cardiac arrest in 12 (0.12%) and in 19 (0.19%) there were other undesirable effects (weakness, nausea, hypotension, flush, urtica etc.). Ionic and non-ionic CS participated equally in complications: ionic CS in 53 (49.5%) cases and non-ionic CS in 54 (50.5%), whereby no difference was observed in the type of complications. No death in conjucntion with administration of CS was observed. CONCLUSION: The use of contemporary contrast substances in the catheterization laboratory for diagnostic and intervention procedures on the heart is relatively safe with a minimal risk of development of serious complications. No difference was observed between the use of ionic and non-ionic CS.

Tremors in Parkinson's disease: symptom analysis and rating.

The object of the present study was to evaluate the hand tremor occurring under various conditions in 81 patients with Parkinson's disease (PD) and to statistically analyze their relation to clinical rating items. We found that resting and action tremor have to be separated, whereas postural tremor can be related to either one of them. Resting tremor does not correlate with disability items or performance items except for an item rating social handicaps. Action tremor shows some influence on performance items. Current rating scales of PD represent a valid measure of resting tremor but are less valid for the measurement of action tremor.

Identification of PCB's in the presence of DDT-type compounds using low temperature luminescence.

Low temperature (77 degrees K) luminescence spectra of polychlorinated biphenyls (PCB's), DDT-type compounds and mixtures suggest a simplified method for identification and quantitation of aromatic pesticides with minimal prior sample treatment. Spectral differences allow identification of PCB's in the presence of DDT and the converse. Approximate detection limits, possible interferences and suggestions for further work are discussed