A case of successful pregnancy and delivery after brain metastasis of choriocarcinoma.

This is report regarding a 28-year-old woman who conceived and delivered a healthy child following treatment for brain metastasis of choriocarcinoma in 1980 and a prolonged postoperative disease-free period. The patient had delivered a hydatidiform mole. Eight months afterwards she was admitted to our hospital with occipital pain, vomiting and stupor, and upon CT examination was found to have a brain tumor. The surgically removed tumor was pathologically diagnosed as choriocarcinoma. Postoperative methotrexate chemotherapy rapidly lowered the preoperative urinary human chorionic gonadotrophin (19 IU/ml), and allowed restoration of the preoperative LH level, consciousness, ambulation, and manifest ovulation. Occasional mild cramps were received by continuous use of anticonvulsants which did not affect her daily life. Four and one-half years postoperatively she conceived, and had a healthy boy weighing 2,294 g at the 39th week of gestation in June 1985. Both mother and baby have been doing well for 7 postpartum years.

Secretory carcinoma of the endometrium.

A case of secretory carcinoma of the endometrium in a 21-year-old woman is reported. Endometrial smears were interpreted as showing a differentiated adenocarcinoma. Smears of ascitic fluid obtained during subsequent surgery showed similar findings; periodic acid-Schiff staining of the smears revealed abundant positive material in the cytoplasm. These findings were interpreted as evidence of secretory carcinoma, which was confirmed by histopathologic study of the biopsy and surgical specimens.

[Survey of screening for uterine cervical cancer in Wakayama city (author's transl)].

3,261 women participated in a questionnaire concerning screening for uterine cervical cancer with the following results: 1. 6.3% reported undergoing cervical cancer screening at intervals of one year or less, and 9.0% at intervals of two years or less, 22% reported having had a screening test at least once. 2. According to age group, 14.7% of women in their fifties had undergone screening; 11.3% in the forties; 10.1% in the thirties, while a sharp decrease to 2.9% was noted for women in their sixties. 3. Among those who had not been screened, an average of about 49% stated their willingness to do so. 60% of those in the age group between 30 and 59 were willing to be screened as compared to only 28% of those over 60. 4. Reasons given for not participating in the screening were as follows: Too busy 34.1%, Bashfulness 23.1%, Fear 13.9%, Overconfidence 15.5%, Old age 2.3% Reasons given differed from the younger group versus those over 60. Between 1979-1980, 4,258 women were screened at Wakayama Rosai Hospital with the following findings: In 0.73% carcinoma in situ, early invasive carcinoma (Stage Ia) was found. In 0.28% Stage Ib-II was found. In 0.19% Stage III-IV was present. In those women having carcinoma over 60 years of age, Stage III-IV was found in 57.9%. We conclude that there is an urgent need to increase the percentage of women undergoing cancer screening in Wakayama. An all-out effort to develop an awareness in women of all age groups of the importance of cancer screening and the promotion of mass screening are called for.