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Pak J Pharm Sci ; 32(3 Special): 1409-1413, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31551222

RESUMO

To observe and analyze the therapeutic efficacy of high-dose ambroxol in the treatment of severe pneumonia, as well as summarize the nursing methods. A total of 180 patients diagnosed with severe pneumonia and treated at our hospital who were enrolled. The patients were divided into a control group and are search group, with 90 patients in each group. Of those, patients in the research group were treated with high-doses ambroxol, while small-dose ambroxol was administered to patients in the control group. The therapeutic efficacy was compared between both groups. Meanwhile, predictive nursing regimens were applied on patients in the research group, while routine nursing care was given to patients in the control group. The nursing satisfaction was compared between both groups. By comparing the pulmonary function indicators, Comparison of procalcitonin (PCT) and C-reactive protein (CRP) results showed that all indicators of the research group were obviously better than those of the control group (p<0.05). The time of infection control, ICU stay and hospital stay of the research group were significantly less than those of the control group (p<0.05). Moreover, the overall nursing satisfaction of the research group was significantly higher than that of the control group (p<0.05).Application of high-dose ambroxol and scientific nursing methods could significantly improve the therapeutic efficacy in the treatment of severe pneumonia and gain favorable nursing satisfaction.


Assuntos
Ambroxol/administração & dosagem , Expectorantes/administração & dosagem , Cuidados de Enfermagem , Pneumonia/tratamento farmacológico , Administração Intravenosa , Adulto , Idoso , Ambroxol/uso terapêutico , Proteína C-Reativa/análise , Relação Dose-Resposta a Droga , Expectorantes/uso terapêutico , Feminino , Humanos , Unidades de Terapia Intensiva , Pulmão/diagnóstico por imagem , Pulmão/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Pneumonia/diagnóstico por imagem , Pró-Calcitonina/sangue , Resultado do Tratamento , Adulto Jovem
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