Association between school bullying and the early age at menarche among girls / 中国学校卫生

Objective@#To analyze the correlation between school bullying and the age at menarche (AAM) in girls, so as to provide references for promoting the healthy growth of girls in puberty.@*Methods@#In April 2022, a total of 987 middle school girls with onset of menarche in Rongchang District of Chongqing were selected by using a stratified random cluster sampling method to carry out a questionnaire survey and physical examination. The t tests,variance analysis and Dunnett t tests were conducted to analyze the differences between individuals who experienced different types of school bullying and AAM. Multivariate Logistic regression analysis was conducted to analyze the association between school bullying and the early age at menarche.@*Results@#The average AAM of 987 girls was (12.13±1.03) years, and 22.90% of them had early AAM. The AAM of those who did not experience bullying events (12.18±0.96) varied significantly with those who experienced bullying events (11.86±1.44) ( t=3.71, P <0.01). The average AAM of individuals who experienced 1, 2, 3 or more school bullying events was (12.08±1.38, 11.74±1.07, 11.61± 1.63 ) years old, respectively. There was a statistically significant difference in AAM between girls who did not experience school bullying and those who experienced 1, 2, 3 or more types of school bullying ( F=6.99, P <0.01). Multivariate Logistic regression analysis found that after adjusting confounding factors, experiencing school bullying ( OR=2.71, 95%CI =2.04-4.27), being deliberately excluded from collective activities or being isolated ( OR=2.58, 95%CI =1.69-4.67), being kicked, pushed or locked in the house ( OR= 2.85 , 95%CI =1.39-4.92), being teased due to physical defects or appearance ( OR=2.74, 95%CI =1.77-5.02), experiencing one school bullying event ( OR=2.33, 95%CI =1.52-4.23), and experiencing two school bullying events ( OR=3.36, 95%CI = 1.82 -7.36), and experiencing three or more school bullying events ( OR=2.89, 95%CI =1.74-5.71) were associated with the early age at menarche ( P <0.05).@*Conclusion@#School bullying is related to the earlier AAM among girls. Strengthening school anti bullying education might be helpful for promoting girls healthy growth and development in adolescence.

Effects of combined administration of calcium, iron, zinc, chrysanthemum flavonoids, and DMSA on the treatment of lead intoxication in mice.

The effect of combined administration of calcium (Ca), iron (Fe), zinc (Zn), chrysanthemum flavonoids, and meso-2,3-dimercaptosuccinic acid (DMSA) on the treatment of lead (Pb) intoxication in mice was studied. One hundred ninety female mice (SPF level, aged 18-22 days) were randomly divided into two groups as experimental animals. Mice in group I (10 mice) served as normal control animals, and were administered deionized water containing 12.5 µL/L acetate acid for 6 weeks, whereas mice in group II (180 mice) were exposed to 0.1% (wt/vol) of lead acetate in deionized water for 6 weeks and served as experimental animals. After 6 weeks of successful modeling, 180 mice from group II (lead-exposed) were divided into 18 groups of 10 mice each, 16 of which were treated by the combined administration of Ca, Fe, Zn, chrysanthemum flavonoids, and DMSA by L16 (215 ) orthogonal design. The remaining two groups were given treatment with low and high doses of DMSA, respectively. After three weeks of intervention (ig), the optimal treatment group was identified according to its blood lead level, as well as some antioxidant indices in the blood, liver, and hippocampus. The results indicated that the combined administration of Fe, Zn, chrysanthemum flavonoids, and DMSA with low dosage had the most significant effect on increasing the activities of blood delta-aminolevulinic acid dehydratase and superoxide dismutase (SOD), hepatic SOD and hippocampus nitric oxide synthase while decreasing the blood lead level, the content of hepatic malondialdehyde and hippocampus nitric oxide; this was considered the optimal treatment group. There was no difference in the level of blood hemoglobin between the optimal treatment group and the model control group (the first group of the orthogonal experiment). The activities of blood glutathione (GSH), hepatic GSH and glutathione peroxidase of the optimal treatment group were the same as other groups', and the recovery of the related indexes in the optimal effect group closely resembled the high dosage DMSA group. It can be concluded that the coadministration of Fe, Zn, and chrysanthemum flavonoids along with a low-dose DMSA effectively reduces Pb poisoning and lead-induced oxidative damage in lead-exposed mice; the result may provide a theoretical reference for the treatment of Pb poisoning.

Research on the present situation of WeChat public accounts of college psychological health education in Hunan Province / 中国学校卫生

Objective@#To explore the application present situation of the WeChat public accounts of colleges psychological health education in Hunan Province, and to provide a scientific reference for strengthening the construction of WeChat public accounts of colleges psychological health education.@*Methods@#The WCI(WeChat Communication Index) of the WeChat public accounts of college psychological health education in Hunan province, the numbers of reading and watching of the push articles which were published during period between June 1 and June 30 in 2019 were collected through the Qingbo data platform. The characteristics of the top 10 articles in reading numbers were analyzed.@*Results@#Totally 19 universities in Hunan Province opened WeChat public accounts of psychological health education, accounting for 51.16% of all universities in Hunan Province. In June 2019, the average WCI of the WeChat public account of college psychological health education in Hunan Province was(159.3±81.3), with 267 articles and average(15.7±14.9). The total number of reading was 38 921, and the average reading number of the articles was 145.8. The total number of watching was 607, and the average watching number of articles was 2.3. Eight articles of the the top 10 articles in reading number were from the top 3 WeChat public accounts in WCI. Four articles were about online and offline interaction and the content of the other 6 articles combined with hot current events, closed to college students’ lives in the top 10 articles in reading numbers. Two articles of the the top 10 articles in reading numbers were film.@*Conclusion@#The proportion of the universities which have opened the WeChat Public account of psychological health education in Hunan Province is not very high, and the dissemination of the WeChat Public accounts of college psychological health education is not very strong. The construction quality of WeChat public account is an important factor affecting the reading number of push article. The articles with content combining with current hot events and closing to college students’ life have higher reading number than the other articles. Video work are more popular than text articles.