1.
Org Biomol Chem
; 22(14): 2780-2790, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38498332
RESUMO
An N-iodosuccinimide (NIS) catalyst was developed for use in the non-traditional synthesis of amide derivatives from nitroalkanes and amines. In contrast to traditional oxidative catalysis, this catalytic system involves reversing the polarities of two catalytic components (umpolung) by means of a hypervalent iodine reagent. A variety of functional groups were tolerated in the reaction, suggesting that they have the potential for use in other types of oxidative catalytic reactions.