An innovative low-cost breast pump-hire program to enhance breastfeeding rates in a neonatal intensive care unit.

AIM: To evaluate the outcomes of a low-cost hospital-grade breast pump hire program for women experiencing financial hardship with infants in neonatal intensive care. DESIGN: A multi-method evaluation including data audits and surveys. METHODS: Twenty-four electric breast pumps were purchased and rented to mothers at a cost of $1/day. To be eligible, mothers needed to have given birth to an infant <32 weeks and/or <1500 g and self-identified as experiencing financial hardship. Data were collected by (1) a retrospective audit to evaluate infant feeding and clinical outcomes at hospital discharge; (2) prospective telephone surveys to evaluate women's satisfaction with the program; and (3) analysis of the breast pump register to determine any loss or damages. RESULTS: Twenty-four mothers of 26 infants participated in the program. More than half of the infants were exclusively breastmilk fed at hospital discharge, and more than three-quarters were fed a combination of breastmilk and formula. Women who intended to formula feed were supported to provide breastmilk to their infants in the first few weeks of life. Most participants were highly satisfied with the program. Women reported that accessibility to a hospital-grade breast pump improved their ability to provide expressed breastmilk to their infants. Most participants were 'extremely satisfied' with the performance of the breast pump. One-quarter of the women reported that they would have exclusively formula-fed if they did not have access to the breast pump hire program. The audit of the equipment register showed no reported technical issues, loss or damages. CONCLUSION: The findings suggested that the low-cost breast pump hire program supported equitable care, increasing women's ability to provide expressed breastmilk for their infants. IMPACT: Providing access to low-cost hospital-grade breast pumps to mothers of vulnerable infants is likely to prevent poor infant clinical outcomes and improve women's care satisfaction. PUBLIC OR PATIENT CONTRIBUTION: Nil.

Development of the national consensus statement on ear health and hearing check recommendations for Aboriginal and Torres Strait Islander children aged under 6 years attending primary care: systematic scoping review and e-Delphi.

BACKGROUND: Early detection of long-term, often asymptomatic, middle ear infection in young Aboriginal and Torres Strait Islander children is more likely to be achieved when ear health and hearing checks are routinely undertaken in primary healthcare. Evidence consistently demonstrates the adverse impacts of this condition on the development and wellbeing of children and their families. We aimed to develop feasible, evidence- and consensus-based primary healthcare recommendations addressing the components and timing of ear health and hearing checks for Aboriginal and Torres Strait Islander children aged under 6 years, not already known to have, nor being actively managed for, ear and hearing problems. METHODS: A 22-person working group comprising Aboriginal and Torres Strait Islander and non-Indigenous members from the primary healthcare, ear, hearing, and research sectors provided guidance of the project. A systematic scoping review addressed research questions relating to primary health ear health and hearing checks for Aboriginal and Torres Strait Islander and other populations at increased risk of persistent ear health problems. Twelve primary studies and eleven guidelines published between 1998 and 2020 were identified and reviewed. Quality and certainty of evidence and risk of bias ratings were completed for studies and guidelines. In the absence of certain and direct evidence, findings and draft recommendations were presented for consensus input to a 79-member expert panel using a modified e-Delphi process. Recommendations were finalised in consultation with working group members and presented to expert panel members for input on considerations relating to implementation. RESULTS: Overall, the quality, certainty, and directness of evidence in the studies and guidelines reviewed was low. However, the findings provided a basis and structure for the draft recommendations presented during the consensus-building process. After two e-Delphi rounds, seven goals and eight recommendations on the components and timing of Ear Health and Hearing Checks in primary healthcare for young Aboriginal and Torres Strait Islander children were developed. CONCLUSIONS: The systematic scoping review and consensus-building process provided a pragmatic approach for producing strong recommendations within a reasonably short timeframe, despite the low quality and certainty of evidence, and paucity of studies pertaining to primary healthcare settings.

'It wasn't the strategies on their own': Exploring caregivers' experiences of accessing services in the development of interventions for autistic people with intellectual disability.

LAY ABSTRACT: Many autistic individuals with intellectual disability experience anxiety, and for those who use few or no words, anxiety may present as behaviour that challenges, such as self-injury and avoiding anxiety-provoking situations. Families report difficulty accessing support from services for autistic individuals experiencing anxiety. Moreover, once receiving support, effective interventions for autistic people with intellectual disability are limited. We completed individual and group discussions with 16 caregivers of autistic people with intellectual disability, to (a) explore their experiences of accessing services for anxiety and/or behaviour that challenges for their child; and (b) understand what matters to caregivers when developing interventions that have been designed for them and the autistic individual with intellectual disability that they support. Caregivers reported that services, in their experience, did not deliver the support that they expected, and that they often needed to 'fight' for support. Caregivers considered services and families working together, the inclusion of peer support, and families being offered interventions that are flexible to individual circumstances to be important. These considerations are valuable for clinicians and researchers developing interventions and aiming to improve outcomes for autistic people with intellectual disability and their families.

Endorsement of scientific inquiry promotes better evaluation of climate policy evidence.

Public and scientific consensus about climate change do not align. Problematically, higher scientific knowledge has been associated with lower acceptance of climate information among those with more conservative socio-political ideologies. Positive attitudes towards science can attenuate this effect. We investigated the association between endorsement of scientific inquiry (ESI) and decision-making with scientific evidence about climate policies. Participants rated support for 16 climate policies accompanied by weaker or stronger evidence. In study 1 (N = 503), higher ESI was associated with greater discernment between strongly and weakly evidenced climate policies, irrespective of worldview. In studies 2 (N = 402) and 3 (N = 600), an ESI intervention improved discrimination, and, in study 3, increased ESI specifically for hierarchical/individualistic participants. Unlike ESI, the link between scientific knowledge and evaluation of evidence was influenced by worldview. Increasing ESI might improve the evaluation of scientific evidence and increase public support for evidence-based climate policies. Supplementary Information: The online version contains supplementary material available at 10.1007/s10584-023-03535-y.

Association of Brain Natriuretic Peptide Levels at Time of Injury with Morbidity and Mortality in Patients with Surgically Treated Hip Fractures.

An elevated brain natriuretic peptide (BNP) level has been shown to be associated with mortality and cardiac events in cardiac surgery, but its utility in the prediction of morbidity and mortality in hip fracture surgery is unknown. The primary aim of this study was to determine if there is a difference in BNP level at the time of injury between patients who do and do not develop complications after hip fracture surgery. The secondary aim was to determine if there is a predictive relationship between complications associated with the initial BNP level and mortality. Methods: A retrospective chart review of 455 hip fractures in patients ≥60 years old that were operatively treated between February 2014 and July 2018 was performed. Patients were included if they had a BNP level within 48 hours after injury (BNPi). Specific perioperative (≤7 days), 30-day, 1-year, and 2-year postoperative complications were recorded. Wilcoxon rank-sum tests were used to determine if higher BNPi values were associated with greater morbidity. The complications associated with higher BNPi values were further analyzed to assess if they were predictive of mortality, using univariate and multivariable analyses. Results: Higher BNPi was significantly associated with greater morbidity at all postoperative time points and with higher mortality at 1 and 2 years postoperatively. Furthermore, several complications including cardiac failure or exacerbation and altered mental status were associated with mortality at all time points in univariate analysis and at many time points in multivariable analysis. Conclusions: Patients with higher BNPi levels were more likely to develop complications up to 1 year postoperatively, and several of these complications were associated with increased mortality. Future studies to determine if delaying surgery until BNP levels are normalized or lowered may help guide management, and may be useful in determining the need for further medical optimization. Future studies aimed at defining a threshold BNP value at the time of injury may also help in better managing patients preoperatively. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Comparison of the Effect of Different Conditioning Media on the Angiogenic Potential of Hypoxia Preconditioned Blood-Derived Secretomes: Towards Engineering Next-Generation Autologous Growth Factor Cocktails.

Hypoxia Preconditioned Plasma (HPP) and Serum (HPS) are regenerative blood-derived growth factor compositions that have been extensively examined for their angiogenic and lymphangiogenic activity towards wound healing and tissue repair. Optimization of these secretomes' growth factor profile, through adjustments of the conditioning parameters, is a key step towards clinical application. In this study, the autologous liquid components (plasma/serum) of HPP and HPS were replaced with various conditioning media (NaCl, PBS, Glucose 5%, AIM V medium) and were analyzed in terms of key pro- (VEGF-A, EGF) and anti-angiogenic (TSP-1, PF-4) protein factors, as well as their ability to promote microvessel formation in vitro. We found that media substitution resulted in changes in the concentration of the aforementioned growth factors, and also influenced their ability to induce angiogenesis. While NaCl and PBS led to a lower concentration of all growth factors examined, and consequently an inferior tube formation response, replacement with Glucose 5% resulted in increased growth factor concentrations in anticoagulated blood-derived secretomes, likely due to stimulation of platelet factor release. Medium substitution with Glucose 5% and specialized peripheral blood cell-culture AIM V medium generated comparable tube formation to HPP and HPS controls. Altogether, our data suggest that medium replacement of plasma and serum may significantly influence the growth factor profile of hypoxia-preconditioned blood-derived secretomes and, therefore, their potential application as tools for promoting therapeutic angiogenesis.

Comparing outcomes in the treatment of pediatric and adolescent intraarticular radial head fractures.

Intraarticular radial head (IARH) fractures are uncommon pediatric injuries with unpredictable yet poor outcomes. The aim of this study was to evaluate clinical outcomes of IARH fractures in pediatric and adolescent patients, by testing our hypothesis that surgically managed fractures would have less risk for an unplanned second surgery and better elbow range of motion at the final follow-up. A retrospective review of 53 IARH fractures was performed. Demographic and clinical data were recorded. Concomitant and associated injuries were documented. Initial management and any attempted reduction in the emergency room were documented. The primary outcome was the need for an unplanned second procedure. Motion at final follow-up, presence of pain and need for physical therapy were reviewed. Radiographs were carefully reviewed and analyzed for physeal status, displacement, angulation and percent of radial head involved. We rejected our hypothesis, however, because it was displaced fractures that tended to require an unplanned change in treatment at a higher rate than nondisplaced fractures, regardless of index management with or without surgery. Fracture displacement on the lateral radiograph was a significant risk factor compared to the anterior-posterior images, and younger patients, particularly those with open physis, were at higher risk of an unplanned second procedure. Moreover, 80% of displaced fractures had asymmetric elbow motion after healing was achieved. It is important to counsel patients and families regarding the potential for suboptimal outcomes and elbow stiffness regardless of treatment choice, in the setting of an initially displaced IARH fracture. Level of evidence: Level III.

Health promotion programs for middle-aged adults that promote physical activity or healthy eating and involve local governments and health services: A rapid review.

BACKGROUND: Noncommunicable diseases can be prevented or delayed through health promotion programs. Little is known about programs delivered by partnership organisations that address lifestyle behaviours. The study's purpose was to review the literature on physical activity or healthy eating health promotion programs, delivered in partnership by the local government and local health services, to describe characteristics of programs and their impact on physical activity, healthy eating or related health outcomes among middle-aged adults. METHODS: This rapid review was conducted from November 2021 to June 2022, informed by the Cochrane Rapid Reviews Methods guidance for conducting rapid reviews. Articles published in English since 2000 were identified in Medline, Embase, CINAHL, AgeLine and Scopus databases. A narrative synthesis was performed. RESULTS: Ten articles involving 19 802 participants were identified from a total of 4847 articles identified from the search. The primary role of the partnership was providing funds. Other roles were facilitating stakeholder involvement, program development, delivery and recruitment. Positive outcomes were likely if programs were developed by collaborative stakeholder partnerships, informed by previous research or a behaviour change framework. The heterogeneity of study designs and reported outcomes did not permit meta-analysis. CONCLUSION: This review highlights the lack of evidence of local government-health service partnerships delivering physical activity or healthy eating health promotion programs for middle-aged adults. Programs designed collaboratively with an evidence base or a theory base are recommended and can guide future work investigating strategies for partnership development. SO WHAT?: Physical activity or healthy eating health promotion programs need early stakeholder collaborative input designed with a theory/evidence base. This can guide future work for investigating strategies for partnership development.

Utilising Interview Methodology to Inform the Development of New Clinical Assessment Tools for Anxiety in Autistic Individuals Who Speak Few or no Words.

Autistic individuals with intellectual disability who speak few or no words are at high risk of anxiety but are underrepresented in research. This study aimed to describe the presentation of anxiety in this population and discuss implications for the development of assessments. Interviews were conducted with 21 parents/carers of autistic individuals and nine clinicians. Data were analysed using content analysis and interpretative phenomenological analysis. Anxiety behaviours described by parents/carers included increased vocalisation, avoidance and behaviours that challenge. Changes to routine were highlighted as triggering anxiety. Clinicians discussed the importance of identifying an individual's baseline of behaviour, knowing an individual well and ruling out other forms of distress. This study raises considerations for early identification of anxiety and for subsequent support.

Quadriplegia from cervical osteomyelodiscitis with vertebral collapse: A case report.

Vertebral osteomyelitis is a rare clinical condition accounting for 1%-7% of all bone-related infections. The increase in chronic diseases such as diabetes mellitus or those that lead to immunosuppression, the increase in spinal instrumentation including epidural catheters for pain management, and the continual increase in intravenous (IV) drug use are factors that have led to the rise in cases. The condition may present subtly without clinical signs and symptoms making early diagnosis difficult. Here, we present a rare case of spontaneous osteodiscitis of the cervical spine complicated by epidural abscess/phlegmon, burst fracture, and spinal cord injury due to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in a patient with a history of intravenous drug use who presented with neck pain. The patient was treated with IV antibiotics and decompressive surgery and, however, was unable to regain the mobility of the lower extremities and regained only slight mobility in the upper extremities leading to an ultimate diagnosis of functional quadriplegia.

The U.S. Armed Services Blood Program support to U.S. Central Command 2014-2021: Transformation of combat trauma resuscitation through blood product innovation and expansion of blood availability far forward.

BACKGROUND: The United States Armed Services Blood Program (ASBP) faced complex blood supply challenges during two decades of military operations in the U.S. Central Command (CENTCOM) and through an adaptive, responsive, and agile system, gained valuable insights on blood product usage in combat casualty care. STUDY DESIGN AND METHODS: A retrospective review of blood product introduction and utilization trends was compiled from ASBP data collected during CENTCOM operations from 2014 through 2021. RESULTS: During the study period, several blood products were introduced to the CENTCOM area of operations including Low Titer O Whole Blood (LTOWB), Cold-Stored Platelets (CSP), Liquid Plasma (LP), and French Freeze Dried Plasma (FDP) manufactured from U.S. sourced donor plasma, all while expanding Walking Blood Bank capabilities. There was a gradual substitution of component therapy for whole blood; blood utilization peaked in 2017. Transfusion of Fresh Whole Blood (FWB) from Walking Blood Banks decreased as fully pre-tested LTOWB was supplied by the ASBP. LTOWB was initially supplied in citrate-phosphate-dextrose (CPD) anticoagulant (21-day shelf life) but was largely replaced with LTOWB in citrate-phosphate-dextrose-adenine (CPDA-1) anticoagulant (35-day shelf life) by 2019. Implementation of prehospital transfusion and expansion of surgical and resuscitation teams led to an increase in the number of sites receiving blood. DISCUSSION: ASBP introduced new products to its inventory in order to meet changing blood product demands driven by changes in the Joint Trauma System Clinical Practice Guidelines and operational demands. These products were adopted into clinical practice with a resultant evolution in transfusion strategies.

Factors influencing surgical decision-making in pediatric and adolescent scaphoid fractures.

We aimed to assess the risk of conversion to surgical intervention in children initially managed with casting for an isolated scaphoid fracture with a secondary aim of assessing the incidence and management of occult scaphoid fractures without signs of fracture on initial radiographs. A retrospective review was performed. Our primary outcome was conversion to surgery. Subsequent evidence of fracture in those with only initial snuffbox tenderness was recorded for the secondary aim. Three hundred and eighty-four wrists with radiographic evidence of a scaphoid fracture were included. Twenty-one scaphoid fractures failed conservative treatment. Subjects that failed cast treatment were older than those that did not (15.9 years vs. 14.0 years; P < 0.001). Subjects with a delay in treatment of at least 6 weeks from injury were 8× more likely to require surgery than those with prompt treatment ( P < 0.001). Surgical conversion varied based on fracture location: distal pole 0.7%, waist 7.4%, and proximal pole 23.5% of the time ( P < 0.001). A total of 14% of wrists managed in a cast without radiographic evidence of fracture at presentation subsequently demonstrated a fracture on follow-up films. The primary predictor of failed conservative treatment is a delay in presentation. We found that the sequelae of delay in presentation or diagnosis of a scaphoid fracture increased the likelihood of requiring surgery. Therefore, clinical suspicion should dictate early management and these factors should play a role in determining when to initiate casting in the setting of pediatric scaphoid fractures. Level of evidence: III.

Psychosocial and Physiological Factors Affecting Selection to Regional Age-Grade Rugby Union Squads: A Machine Learning Approach.

Talent selection programmes choose athletes for talent development pathways. Currently, the set of psychosocial variables that determine talent selection in youth Rugby Union are unknown, with the literature almost exclusively focusing on physiological variables. The purpose of this study was to use a novel machine learning approach to identify the physiological and psychosocial models that predict selection to a regional age-grade rugby union team. Age-grade club rugby players (n = 104; age, 15.47 ± 0.80; U16, n = 62; U18, n = 42) were assessed for physiological and psychosocial factors during regional talent selection days. Predictive models (selected vs. non-selected) were created for forwards, backs, and across all players using Bayesian machine learning. The generated physiological models correctly classified 67.55% of all players, 70.09% of forwards, and 62.50% of backs. Greater hand-grip strength, faster 10 m and 40 m sprint, and power were common features for selection. The generated psychosocial models correctly classified 62.26% of all players, 73.66% of forwards, and 60.42% of backs. Reduced burnout, reduced emotional exhaustion, and lower reduced sense of accomplishment, were common features for selection. Selection appears to be predominantly based on greater strength, speed, and power, as well as lower athlete burnout.

A comparison of cone beam computed tomography, standard computed tomography and plain radiographs in the evaluation of medial epicondyle humerus fractures.

The ideal technique to measure medial epicondyle humerus fracture displacement minimizes radiation exposure while maximizing measurement accuracy and reliability. This study compares the radiation exposure and accuracy of displacement measurements of the four-view X-ray examination (XR), computed tomography (CT) and in-clinic cone-beam CT (CBCT). A cadaveric humerus underwent medial epicondyle osteotomy. The fragment was fixed to the humerus at clinically relevant displacements (6 to 18 mm). Dosimeters were placed around the distal humerus and simulating thyroid location. XR, CT and CBCT were performed at each displacement. Four pediatric orthopedists measured the maximum linear displacement on each XR and 3D reconstruction of the CT and CBCT images. Focal (elbow location) and thyroid radiation exposure was compared between modalities. Intra- and interclass correlation coefficients (ICC) for displacement measurements were determined. Mean focal radiation exposures for XR, CT and CBCT were 0.008, 2.061 and 0.478 rad, respectively (P = 0.001). Exposures 10 inches from the elbow for XR, CT and CBCT were 0.001, 0.066 and 0.010 rad, respectively (P = 0.006). At 12 inches, there was no significant difference in exposure between XR and CBCT ( P = 0.114). Intra- and interobserver reliabilities were excellent for all measures, except lateral x-ray. CBCT and CT had significantly less deviation from the actual displacement compared to XR ( P < 0.05). In-office CBCT of the elbow exposes patients to significantly less radiation than conventional CT. All X-ray images (except lateral), CT and CBCT had equal reliability in evaluating medial epicondyle fractures, which contrasts with previous evidence.

Treatment of Hip Instability in Children With Down Syndrome: Keys to Managing a Challenging Problem.

INTRODUCTION: Management of hip instability in children with Down syndrome is a challenging task to undertake for even the most experienced surgeons. As life expectancy of these patients increases, the importance of preserving functional mobility and hip joint stability in order to minimize late hip degeneration and pain has become a priority. The aim of this study is to evaluate the clinical and radiographic outcomes of children with Down syndrome and hip instability who underwent surgical reconstruction with femoral and/or acetabular procedures. METHODS: We performed a retrospective review of all children with Down syndrome age 18 years and younger, who underwent surgical intervention to address hip instability between 2003 and 2017. Data was recorded detailing the patient's demographics, preoperative and postoperative functional status and surgical details. Preoperative and postoperative radiographic analysis was performed as well as 3-dimensional computed tomography scan evaluation, when available. All major and minor complications were recorded and classified using the Severin radiographic classification and the Clavien-Dindo-Sink clinical classification. RESULTS: We studied 28 hips in 19 children that were followed for an average of 4.4 years postsurgical intervention for hip instability. The majority of patients improved in all radiographic parameters. A total of 14 hips (50%) had complications and 9 hips (32%) required a secondary surgery. Of those complications, 2 hips (7%) developed avascular necrosis and 4 hips (14%) developed recurrent instability after the index procedure. Two of these hips had a subsequent anteverting periacetabular osteotomy that produced a stable hip at final follow up. DISCUSSION: Surgical management of hip instability in children with Down syndrome remains challenging. The treating surgeon must have a thorough understanding of the pathoanatomy and design the surgical treatment to meet all of the underlying sources of instability. Combined femoral and acetabular osteotomies plus capsulorrhaphy are often required along with postoperative hip spica immobilization. Although complication and revision surgery rates are high, hip stability and good functional outcomes can be achieved.

Distal tibial osteotomy to address internal tibial torsion: Should the fibula be cut?

Background Rotational tibial osteotomy seeks to address pathologic tibial torsion. Inclusion of fibular osteotomy during this procedure remains controversial. This study aimed to determine how external rotation through a tibial osteotomy, with or without a fibular osteotomy, would influence tibiofibular joint congruity. Methods Eight cadaveric legs underwent distal tibial osteotomies. Pins were placed to designate neutral, 10°, 20°, 30° of external rotation. Computed tomography (CT) imaging was performed at each rotation without, then with a fibular osteotomy. Magnetic Resonance Imaging was performed prior to fibular osteotomy to confirm that ligaments remained intact. Custom software calculated tibial torsion using CT scan 3D reconstructions. Proximal tibiofibular joint rotation, distal tibiofibular gapping and ankle mortise were measured on each CT exam. Groups without and with fibular osteotomy were compared. Findings There was no difference between tibial osteotomy rotation magnitude with or without the fibular osteotomy (P = 0.2). The group without the fibular osteotomy had greater proximal fibular rotation at the tibiofibular joint at 20°, 30° (P < 0.05), greater posterior distal tibiofibular gap at 10°, 20°, 30° (P < 0.05) and less anterior distal tibiofibular gap at 20°, 30° (P < 0.05). The medial tibiotalar space was narrowed without the fibular osteotomy at 20°, 30° (P < 0.05) compared to pre-rotation. Interpretation Deformity at the proximal tibiofibular and ankle joints become most pronounced at >20° of tibial rotation without a fibular osteotomy. The first joint to be affected is the distal tibiofibular joint. To limit ankle and proximal tibiofibular articular deformation during tibia rotational osteotomy, a fibular osteotomy is recommended when correcting over 20° of rotation.

Diversity in the prevalence and correlates of extramarital sex in a probability sample of Latino adults.

Individuals from different Spanish-speaking countries are often combined into a single Latino group. However, this group is diverse, with immigrants and naturalized citizens coming from multiple countries. The present study was conducted to (a) examine potential differences in the annual prevalence of extramarital sex as a function of cultural group (Mexican, Cuban, Puerto Rican, or other Latino) and nativity (born inside or outside the United States) and (b) identify explanations for any observed differences in the prevalence of extramarital sex, drawing on known correlates of extramarital sex and other psychosocial constructs that may be associated with cultural group or nativity that could account for such associations. Results from the National Latino and Asian American Study, a probability sample of Latinos in the United States, indicated that the annual prevalence of extramarital sex was significantly higher among (a) Puerto Ricans relative to Mexicans and (b) foreign-born individuals relative to those born in the United States. Probability of extramarital sex was significantly associated with marital satisfaction and frequency of religious attendance, but these variables did not account for the subgroup differences in the prevalence of extramarital sex. Marital adjustment, acculturation (English proficiency and use), enculturation (ethnic identity), and family cohesion were not significantly associated with probability of extramarital sex. Results underscore the need for continued research on understanding subgroup differences in the prevalence of extramarital sex within the diverse Latino community and identifying characteristics that account for such differences. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Role of inflammatory markers in the preoperative evaluation of patients undergoing salvage total hip arthroplasty.

Surgeons may use laboratory tests, including erythrocyte sedimentation rate, C-reactive protein (CRP), and white blood cell count, as well as joint aspirations to diagnose prosthetic joint infections. There is a paucity of literature correlating preoperative inflammatory markers with risk of infection in the setting of salvage total hip arthroplasty (THA). This retrospective case analysis included patients who underwent a THA salvage procedure a minimum of 3 months after a failed fixation of a proximal femur or acetabulum, with a goal of assessing the utility of inflammatory markers as a screening tool in preoperative evaluation of salvage THA. Eighty-five patients met inclusion criteria. Thirteen patients were diagnosed with an infection preoperatively or intraoperatively during salvage THA. An elevated preoperative CRP level was a significant marker for infection. A CRP of 7.1 produced 80% sensitivity, 88% specificity, and a receiver operating characteristic curve of 0.840. There was a high rate of perioperative complications (17.6%) in salvage THA regardless of the presence of infection. In conclusion, CRP levels are useful in the preoperative evaluation for periprosthetic joint infection before salvage THA.

Breastfeeding practices in an Australian tertiary care hospital: A retrospective study.

BACKGROUND: The World Health Organization recommend that infants be exclusively breastfed until six months of age. The Baby Friendly Health Initiative (BFHI) was developed for protecting, promoting, and supporting breastfeeding. The BFHI global criteria guides hospital practice for supporting infant feeding and reducing disparities in breastfeeding outcomes. AIM: The aim of this study was to analyse 2019 data to identify factors that predict exclusive breastfeeding vs non-exclusive breastfeeding on discharge to determine areas for intervention in relation to BFHI guidelines. MATERIAL AND METHODS: A retrospective chart review of 5836 neonates born at an Australian tertiary hospital in 2019 was conducted. Descriptive statistics were used to report exclusive breastfeeding rates. Univariate and logistic regression analyses were conducted to determine factors associated with exclusive breastfeeding and non-exclusive breastfeeding on discharge. RESULTS: A total of 69% of neonates were exclusively breastfed on discharge in 2019. When excluding admissions to Newborn Services, 75% of neonates were exclusively breastfed on discharge, achieving the BFHI benchmark. Predictors which significantly reduced the odds of exclusive breastfeeding on discharge were maternal country of birth (Vietnam, p < 0.001, Sudan p < 0.001, Samoa p < 0.01, Philippines p < 0.05), main language (Other, p < 0.05), birth type (caesarean or assisted vaginal birth p < 0.001), first-feed type (mixed feeding or formula p < 0.001), and Newborn Services admission (p < 0.001). CONCLUSIONS: Examining breastfeeding outcomes is an important quality assurance process for health services. Understanding groups of mothers who commence breastfeeding but do not exclusively breastfeed upon discharge enables identification of areas for intervention to achieve BFHI targets and reduce breastfeeding disparities.

Effect of interventions for the well-being, satisfaction and flourishing of general practitioners-a systematic review.

OBJECTIVES: Clinician well-being has been recognised as an important pillar of healthcare. However, research mainly addresses mitigating the negative aspects of stress or burnout, rather than enabling positive aspects. With the added strain of a pandemic, identifying how best to maintain and support the well-being, satisfaction and flourishing of general practitioners (GPs) is now more important than ever. DESIGN: Systematic review. DATA SOURCES: We searched MEDLINE, PsycINFO, Embase, CINAHL and Scopus from 2000 to 2020. STUDY SELECTION: Intervention studies with more than 50% GPs in the sample evaluating self-reported well-being, satisfaction and related positive outcomes were included. The Cochrane Risk of Bias 2 tool was applied. RESULTS: We retrieved 14 792 records, 94 studies underwent full-text review. We included 19 studies in total. Six randomised controlled trials, three non-randomised, controlled trials, eight non-controlled studies of individual or organisational interventions with a total of 1141 participants. There were two quasi-experimental articles evaluating health system policy change. Quantitative and qualitative positive outcomes were extracted and analysed. Individual mindfulness interventions were the most common (k=9) with medium to large within-group (0.37-1.05) and between-group (0.5-1.5) effect sizes for mindfulness outcomes, and small-to-medium effect sizes for other positive outcomes including resilience, compassion and empathy. Studies assessing other intervention foci or other positive outcomes (including well-being, satisfaction) were of limited size and quality. CONCLUSIONS: There is remarkably little evidence on how to improve GPs well-being beyond using mindfulness interventions, particularly for interventions addressing organisational or system factors. This was further undermined by inconsistent reporting, and overall high risk of bias. We need to conduct research in this space with the same rigour with which we approach clinical intervention studies in patients. PROSPERO REGISTRATION NUMBER: CRD42020164699. FUNDING SOURCE: Dr Diana Naehrig is funded through the Raymond Seidler PhD scholarship.