[The value of antibiotic prophylaxis in transurethral resection of bladder tumors. Apropos of 61 cases]. / Intérêt de l'antibioprophylaxie au cours des résections transurétrales de tumeurs de vessie. A propos de 61 cas.

In order to define the value of antibiotic prophylaxis, we conducted a prospective, randomised, double-blind, placebo-controlled study in 61 patients undergoing transurethral resection (TUR) of a bladder lesion suspected to be neoplastic. 32 patients received a single dose of 800 mg of pefloxacin at the time of anaesthetic induction and 29 patients received placebo. All patients had sterile preoperative urine and none had received any antibiotics during the fortnight preceding the operation. 3 patients in the pefloxacin group (9.4%) developed postoperative bacteriuria versus 7 in the placebo group (24.1%) (no statistically significant difference). No patient developed symptomatic urinary tract infection. We conclude that antibiotic prophylaxis is not indicated during TUR for bladder tumours.

[Midazolam used for intramuscular premedication in locoregional anesthesia in urology. Usefulness of late premedication]. / Le mizadolam en prémédication intra-musculaire dans l'anesthésie loco-régionale en urologie. Utilité d'une prémédication tardive.

Midazolam was used as an intramuscular premedication combined with atropine in a population of 100 patients receiving loco-regional anaesthesia for urologic procedures. Two different dosages were given according to age: 0.10 mg/kg for patients over 50 years, 0.15 mg/kg for those under 50. This premedication was always effected just before the patient's transport to surgery. We observe the quality of anxiety relief (85%), sedation (82%), anterograde amnesia. These results confirm that midazolam is a suitable drug for late premedication by the intramuscular route. It is a potent drug with regular short-lasting action, which lead us to suggest its use in ambulatory anaesthesia.