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2.
Adv Physiol Educ ; 45(1): 103-108, 2021 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-33544037

RESUMO

The objective of this study was to determine gastrointestinal transit time in first-year health science students with a laboratory practical exercise conducted in two cohorts (classes of 2018 and 2019) of first-year health sciences students at the Health Science Campus in Windhoek, Namibia. All first-year health science students undertaking the Physiology course were invited to take part in the laboratory exercise. The primary outcome was the measurement of gastrointestinal transit time from the amount of time taken for ingested whole-kernel sweetcorn to be eliminated, which was calculated as the time period between ingestion of corn and the time of corn first seen in the stool and the time corn was last seen in the stool. The secondary outcome was an association between emotional irritability and/or anxiety and gastrointestinal transit time. The study analyzed responses of 175 students, who reported a median transit time of 29 (1-99) h. There was no difference in gastrointestinal transit time between male and female students. Likewise, there was no difference in the duration of the corn in the bowel between male and female students. Students who reported being worried and irritable during the exercise had more bowel movements before they saw corn in their stool and had slower transit times, respectively. A wider range of transit time was reported in a group of young, healthy students compared with previous studies in the literature. There were no differences between male and female student bowel activity. Anxiety did impact the bowel activity of the participants.


Assuntos
Trânsito Gastrointestinal , Zea mays , Defecação , Exercício Físico , Feminino , Humanos , Masculino , Estudantes
4.
Int J Clin Pharm ; 42(6): 1528-1532, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33058018

RESUMO

Namibia has previously relied on external training of pharmacists but began in-country training in 2011. In response to an identified need for postgraduate clinical pharmacy development and training in the country, a Master's degree was set up at the University of Namibia in 2016. The country has a considerable health burden of HIV and TB as well as a shortage of healthcare professionals. A UK clinical diploma model was adapted to meet the specific needs of the country and wider region, ensuring students could access the course over a sparsely populated, but large geographical spread, in addition to providing work-based learning, embedding research skills for future development, and focusing on the health needs of Namibia. The course uses online learning platforms and contact sessions to cover both knowledge and skill acquisition throughout the 3 years of the course. UK and US clinical pharmacists are utilised to provide specialist input, both remotely and within student workplaces, and further support has come from collaborations, including cross-site visits, with the UK-based pharmacy school whose diploma model was adapted. Challenges have included a shortage of clinical mentors, also compounding the students' difficulty in visualising their future roles, as well as lone practitioners finding it hard to attend all contact sessions. The initial dropout rates of earlier cohorts have since reduced with greater understanding of the programme, and enthusiasm for the course remains high. The aim for the Master's is to train students to become competent clinical pharmacists, thus having the knowledge and skills to mentor future cohorts of the course, as well as expanding the specialty within the country.


Assuntos
Educação a Distância , Educação de Pós-Graduação em Farmácia , Farmacêuticos/provisão & distribuição , Estudantes de Farmácia , Competência Clínica , Currículo , Humanos , Mentores , Namíbia
5.
Toxins (Basel) ; 12(8)2020 08 14.
Artigo em Inglês | MEDLINE | ID: mdl-32823821

RESUMO

Cobra snakes, including Naja mossambica and Naja nigricincta nigricincta, are one of the major groups of snakes responsible for snakebites in southern Africa, producing significant cytotoxicity and tissue damage. The venom of N. mossambica has been briefly characterised, but that of N. n. nigricincta is not reported. The current study identifies the venom proteins of N. mossambica and N. n. nigricincta. This is achieved using sodium dodecyl sulphate (SDS)-polyacrylamide gel eletrophroresis (PAGE), followed by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Most of the proteins were less than 17 kDa in both snakes. N. mossambica was found to have 75 proteins in total (from 16 protein families), whereas N.n. nigricincta had 73 (from 16 protein families). Of these identified proteins, 57 were common in both snakes. The proteins identified belonged to various families, including the three-finger toxins (3FTx), Cysteine-rich secretory proteins (CRiSP), Phospholipase A2 (PLA2) and Venom metalloproteinase M12B (SVMP). The current study contributes to the profile knowledge of snake venom compositions, which is of fundamental value in understanding the proteins that play a major role in envenomation.


Assuntos
Venenos Elapídicos/química , Naja , Proteínas de Répteis/química , Animais , Cromatografia Líquida de Alta Pressão , Proteoma , Espectrometria de Massas em Tandem
7.
Curr Pharm Teach Learn ; 12(2): 213-219, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-32147164

RESUMO

BACKGROUND AND PURPOSE: Pharmacy and medical training were introduced for the first time in Namibia in 2011 and 2010 respectively. All students must complete a research project as part of their training, which is supported by various courses in the respective curricula including research methods. Following a revision of the medical curriculum, there was an opportunity to review the way research methods was taught for both degrees, piloting in pharmacy then expanding to other disciplines. An educational activity that was part of the research methods course for training pharmacy students in Namibia is described. EDUCATIONAL ACTIVITY AND SETTING: The activity described related to a new approach in the running of the research methods course for pharmacy students and included, in a portfolio-based approach, a group project. Students were tasked to collect qualitative data from medical student colleagues that they then needed to codify and ultimately articulate into a survey questionnaire. The questionnaire was subsequently sent out to collect responses on medicines-related items that could be analyzed quantitatively in subsequent teaching sessions. Supportive lectures, tutorials and portfolio assignments were provided during the project. Data were collected the following year to create a more substantive dataset and a screencast video made to benefit future students in the course. FINDINGS AND DISCUSSION: Through the course of this activity students developed a questionnaire survey tool based on qualitative responses to brief interviews with medical students and emergent themes based on qualitative analyses. A dataset was created that allowed demonstration of quantitative analyses and extraction of sub-scales from the questionnaire. Further educational resources were developed to ensure sustainability of this educational resource and retention in the taught curriculum. SUMMARY: The current article discusses the development, implementation and evaluation of this research methods course component. The application of data collected as part of the activity and its relevance to the educational activity is examined as well as lessons learned for the future running of the project and further evaluation.


Assuntos
Educação em Farmácia/métodos , Pesquisa/educação , Estudantes de Farmácia/estatística & dados numéricos , Currículo/tendências , Educação em Farmácia/normas , Educação em Farmácia/tendências , Avaliação Educacional/métodos , Humanos , Namíbia
8.
Am J Trop Med Hyg ; 101(4): 905-907, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31436159

RESUMO

Training health-care students in settings with high-prevalence HIV and tuberculosis (TB) presents a challenge to reduce the risk of infection during their clinical training while maintaining quality education. We sought to gauge the risk of exposure to HIV and TB and identify associated variables through two cross-sectional surveys of health students at the University of Namibia. In the HIV exposure survey, overall almost one-quarter of students (N = 367) reported exposure to HIV-most often needle-stick injury-with a much higher rate reported in senior years (73% in year 6). One in 10 students responding to the TB survey were found to have been exposed to TB (N = 290). Regression analyses suggested that time-related factors were a common predictor of risk of both HIV and TB in this setting. We consider that the overall exposure rate to HIV and TB was high, suggesting that training could be improved to reduce the risks of exposure.


Assuntos
Infecções por HIV/epidemiologia , Tuberculose/epidemiologia , Adolescente , Estudos Transversais , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Ocupações em Saúde/educação , Humanos , Masculino , Namíbia/epidemiologia , Prevalência , Risco , Estudantes de Ciências da Saúde , Inquéritos e Questionários , Universidades , Adulto Jovem
10.
Lancet ; 393(10167): 129-131, 2019 01 12.
Artigo em Inglês | MEDLINE | ID: mdl-30638578
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