1.
Chemistry
; 30(24): e202400302, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38380868
RESUMO
In this paper, Pd-catalyzed [4+2] decarboxylative cycloaddition of 4-vinylbenzodioxinones with barbiturate-derived alkenes has been developed, leading to various spirobarbiturate-chromane derivatives in high yields with excellent diastereo- and enantioselectivities. The scale-up reaction and further derivation of the product were demonstrated. A plausible reaction mechanism was also proposed.