RESUMO
Background Sustainable and environmentally friendly methods of producing nanoparticles are now being investigated by scientists. Because there are so many marine renewable resources, scientists are focusing their attention on studying seagrass, seaweed, mangroves, marine macroalgae, and microalgae. An exciting new frontier in research involves the synthesis of nanoparticles using extracts from seaweed. Seaweed extracts are utilized to synthesize silver nanoparticles (Ag NPs), which serve as both reducing and stabilizing agents. Seaweed extracts possess bioactive substances like proteins, polysaccharides, and polyphenols that enable them to effectively convert silver (Ag+) ions into Ag NPs. Ag NPs derived from Sargassum seaweed have played an essential role in improving the anti-inflammatory properties of seaweed extracts. This study aimed to investigate the biosynthesis of Ag NPs from Sargassum seaweed and evaluate their anti-inflammatory properties. Materials and methods About 50 g of seaweed samples were mixed with 100 mL of distilled water and stirred for 24 hours. Additionally, 1.2 g of silver nitrate (0.120 M) was dissolved in 60 mL of distilled water to make a silver (Ag) solution. A 60 mL solution of silver nitrate (AgNO3) was mixed with a 40 mL solution of seaweed extract in water, and the mixture was stirred with a stirrer for 24 hours. A UV spectrophotometer was used to regularly monitor the reduction of Ag+ ions in the solution. Ag NPs were purified using a sequence of centrifugation steps with a duration of 10 minutes at a speed of 2500 revolutions per minute (rpm). To remove moisture from the water-suspended nanoparticles, they were vacuum-dried for 24 hours. Results The synthesis of Ag NPs from seaweed extract resulted in a noticeable change in the color of the mixture, which went from pale to brown. The alteration in color signifies the reduction of AgNO3 to Ag+ ions, facilitating the creation of Ag NPs. X-ray diffraction (XRD) measurement verified the remarkable crystallinity of the synthesized Ag NPs. Field emission scanning electron microscopy (FESEM) images indicated a spherical, homogeneous structure. The Ag NPs derived from seaweed exhibited significant anti-inflammatory characteristics. Conclusion Utilizing Sargassum sp. seaweed in the biological synthesis of Ag NPs shows promise to develop nanomaterials that can exhibit anti-inflammatory effects. This technique has benefits, such as being environmentally friendly and cost-efficient. Additional research in this area is essential for effectively exploiting the potential of Ag NPs in anti-inflammatory activity.
RESUMO
Introduction The utilization of Cymodocea serrulata for the eco-friendly synthesis of zinc oxide nanoparticles, which contain distinguishable nanostructures, presents a cost-effective and environmentally sustainable alternative for producing zinc nanoparticles. The production process of zinc nanoparticles are rich in phytochemicals, which can serve as stabilizing and reducing agents. Zinc nanoparticles can easily pass through bacterial cell walls and reach all cellular components. C. serrulata, is a small submerged angiosperm commonly found in submerged and tidal coastal environments. Aim Analysis of the biological activities of zinc oxide nanoparticles made from C. serrulata leaf extract. Materials and Methods Dry leaves of C. serrulata were ground into a powder, which was then placed into a conical flask and filled with water. Subsequently, the color of the mixture turned black. Next, a 20 mm piece of ZnO was dissolved in a 60 ml sample of distilled water to prepare the metal solution. Following this, a wavelength scan ranging from 200 to 700 nm was conducted using ultraviolet (UV) spectroscopy. After shaking the solution for an hour, a final reading was taken across the UV spectrum. The synthetic sample should also be centrifuged to remove any pellets and subsequently dried in a hot air oven. Result Using nanoscale profiling, the average particle size was measured and found to be less than 100 nm, specifically UV spectrum analysis revealed a notable absorbance value of 47.0 nm, at different angles within the peak height. The wavelength range of the zinc nanoparticles was observed to be between 250 and 350 nm. Conclusion The antibacterial properties of ZnO NPs have been demonstrated through in vitro investigations, indicating their potential application in in vivo studies.
