A closer look at bio-hydrogen strategy in post-carbon age and its prospect in Egypt.

The necessity of achieving climate goals has become more pressing during the past two years. Discussions on implementing and achieving these goals have taken place in addition to the tightening of the climate targets and the desire for net-zero attainment by as early as 2050. Along with the capacity of biomass to supply the energy needs of society today being quite significant, hydrogen may be the best choice to replace fossil fuels as a clean energy source. Therefore, this study presents a high-level overview of the bio-hydrogen technical pathways, as well as socioeconomic and ecological aspects of bio-hydrogen, and an analysis of the global hydrogen development. A focus on Egypt, as a prominent spot on the global energy map, could instruct other emerging countries and help policymakers of the national hydrogen agenda to prioritize developing a new legal framework to regulate hydrogen production projects, offering financial incentives to energy-intensive companies to switch to using green hydrogen, and providing transparency and certainty regarding future hydrogen demand possibilities.

Assessing the role of green economy on sustainable development in developing countries.

Purpose: Over the last few years, the green economy (GE) notion has been realized as a key tool for achieving sustainable development (SD) in both developing and developed nations. Therefore, the current study tries to investigate the role of GE in achieving SD in developing countries. Through empirically examining the relationship between the GE and three different dependent variables which are GDP per capita, total unemployment rate, and poverty level, using cross-sectional data for 60 developing countries in 2018. Design/methodology/approach: Applying generalized least square (GLS) approach. The four dimensions of the Global Green Economy Index (GGEI) are the key independent variables that measure the accomplishment of nations in aspects of the global green economy. Findings: The empirical results showed the existence of a positive statistically significant relationship between the GE and GDP per capita and the level of total unemployment, while there is a negative statistically significant relationship between the GE and the poverty rate in developing countries. Implication policy: This study recommends that both the private and public sectors continue to endorse and adopt GE in the future for SD, job creation, and poverty alleviation.The original value of the study: It is the first research for developing countries that explores the relationship between GE and SD using three indicators of SD using a GLS approach according to our information. Also, this study categorized the dataset of the developing countries based on their income level for addressing the heteroskedasticity problem.

Modelling natural gas, renewables-sourced electricity, and ICT trade on economic growth and environment: evidence from top natural gas producers in Africa.

Addressing extensive global goals including growing energy-sourced electricity and advancing sustainable development plans strongly depends on natural gas as a transition fuel to renewable forms of energy. Therefore, by using pooled, random, and fixed-effects models, the current study investigates the effects of electricity sourced from natural gas (ENG), renewable energy (RE), and trade in information and communication technologies (ICTs) on economic growth and carbon dioxide (CO2) emissions in Africa's top three natural gas producers, Algeria, Egypt, and Nigeria, from 1990 to 2020. The findings indicate that CO2, ENG, ICT trade, and urbanization (UP) are all strongly and positively correlated to economic progress, with the exception of RE, which has an insignificant influence. For the environment, data indicate that RE and GDP degrade the environment while ENG and ICT trade boost it. The causality results that ENG and RE cause both economic growth and CO2 emissions. Based on these empirical results, it is recommended that policymakers should step up their efforts to usage natural gas as a transition fuel to renewable energy sources and acknowledge the advantages of the significant contribution that green ICT trade can make to economic advancement and a clean environment.

Assessing environmental concern and its association with carbon trade balances in N11 Do financial development and urban growth matter?

Expanding of complex global supply chains enhances the role of global trade in the deterioration of the environment by production redeployment across nations, which is tightly connected to emission transmission or the carbon trade balance. Although much earlier studies have assessed the link between emissions of carbon dioxide (CO2) and their influenced variables in the past few years, no substantial attention is available in the literature review concerning the influence of carbon trade balance on the environment in N11 economies. Therefore, via economic progress, renewable/fossil energies consumption, financial development, and urbanization growth as control variables, the influence of the carbon trade balance on emissions of CO2 in N11 countries is explored from 1990 to 2020. The Co-integration and causality relationships using Panel PMG ARDL and Granger causality techniques are investigated to reach our goal. All of the variables investigated degrade the environment in the long run, whereas renewables alleviate CO2. As a result, carbon emission countries' regulators should step up their efforts to support green energy subsidies and carbon taxes, as well as, when supply chains outsource emission-intensive production units to partner nations, they should encourage positive externalities of innovative green technologies.

Investigating the potential role of innovation and clean energy in mitigating the ecological footprint in N11 countries.

This paper seeks to explore the potential function of technological innovation and clean power in mitigating the ecological footprint in the N-11 nations during the phase 1992-2015 by applying panel cointegration analysis. The outcomes of the panel cointegration test signify the occurrence of a long-run relation among the clean energy (CE) variable, the ecological footprint (EF) variable, the per capita GDP (Y) variable, the financial development (FIN) variable, and technological innovation (TI) variable. The outcomes of the VECM signify a long-run causal relation from the ecological footprint (EF) variable to the clean energy (CE) variable, the GDP per capita (Y) variable, and technological innovation (TI) variable. This implies that the environmental degradation faced by the N-11 countries leads to shifting toward clean energy sources and technological innovation in the long run. Thus, the N-11 countries are in need to design policies that enhance shifting toward environmentally friendly energy sources.

How do clean energy sources and financial development affect unemployment? Empirical evidence from Egypt.

Reducing unemployment rate to reach 5% is one of the most important priorities in Egypt's Strategy for Sustainable Development. So, enhancing the finance of medium and small enterprises and attracting investors to clean energy resources sectors are considered the most important government's priorities to achieve this strategic goal (UN 2018). Depending on this strategy, the study investigates the long-run and causal relationships between unemployment, financial development, population, and clean energy sources in Egypt from 1971 to 2014. Johansen and Juselius, auto-regressive distributed lag (ARDL), and vector error correction (VECM) approaches are employed to achieve this purpose. The results indicate that while clean energy resources have an adverse effect on unemployment, financial development and population have positive effect. The main findings of VECM reveal the existence of short run one-way causal relation from unemployment to financial development and from population to financial development and alternative energy sources. The main results imply that devoting domestic credit to renewable energy sector can help in providing job opportunities.

IDH Mutations in AML Patients; A higher Association with Intermediate Risk Cytogenetics.

OBJECTIVE: IDH mutations diversely affect the prognosis of cyogenetically normal acute myeloid leukemia (CN-AML) adult patients. The aim of this study is to assess the frequency of IDH mutations and to evaluate its role in AML prognosis. METHODS: We have analyzed IDH1 and 2 mutations using High Resolution Melting curve analysis (HRM) in 70 denovo AML patients. RESULTS: The median age of AML patients is 40 years (16-75). Incidence of IDH mutations is 10/70 (14.3%); 2 (2.9%) IDH1 mutant and 8 (11.4%) IDH2 mutant. Median PB blasts of mutant IDH patients was 67.5% (25-96) vs. 44% (0-98) for wild type (p=0.065). Eight/10 (80%) mutant IDH patients had B.M blasts ≥50% vs. 2/10 (20%) <50% (p<0.001) and were classified as intermediate risk cytogenetics (p=0.020) with wild FLT3-ITD (p=0.001). Ten/10 (100%) mutant IDH patients showed wild NPM1 (p=0.049). Median OS of mutant IDH in the intermediate risk cytogenetics was 1.8 years (0.7-3.1) vs. 3.1 years (1.1-5.5) for wild IDH (p=0.05). CONCLUSION: IDH mutation is mainly associated with intermediate risk AML and when integrated in this specific subgroup displays a lower survival and can be considered an additional integrated molecular risk marker for AML prognosis.
.

Do technological innovations and financial development improve environmental quality in Egypt?

Achieving the seventh Sustainable Development Goal which is clean energy at affordable prices depending on technological innovation is one of the most strategic objectives of Egypt, aiming at mitigating carbon dioxide emissions and enhancing sustainable economic growth (IRENA 2018b). Based upon this goal, the study explores the relationships among carbon dioxide emissions, technological innovation, alternative energy resources, economic growth, and financial development in Egypt over the period 1971-2014. Auto-regressive distributed lag (ARDL), fully modified ordinary least square (FMOLS), Stock and Watson dynamic ordinary least square (DOLS), and Toda-Yamamoto approaches are employed. The results show the existence of cointegration among the variables. Moreover, empirical results show that while technological innovation and alternative energy resources improve environmental quality, financial development and economic growth deteriorate it. The findings obtained from Toda-Yamamoto approach reveal the existence of bi-directional causal relation between environmental degradation and economic growth. Also, environmental degradation causes technological innovation and financial development causes environmental degradation and economic growth. Thus, several policy implications should be suggested to policymakers as enhancing the development of technological innovation especially in renewable energy sector to improve environmental quality.

Impact of FLT3 Receptor (CD135) Detection by Flow Cytometry on Clinical Outcome of Adult Acute Myeloid Leukemia Patients.

BACKGROUND: The significance of FMS-like tyrosine kinase 3 (FLT3)-ITD mutation in acute myeloid leukemia (AML) prognosis has been well established. The aims of this study were to investigate the prognostic impact of the FLT3 protein (CD135) expression and its association with FLT3-ITD mutation, and to identify its role in minimal residual disease. PATIENTS AND METHODS: CD135 was measured by flow cytometry on leukemic blasts of 257 adults with de novo AML. High expression of CD135 ≥ 20% was correlated with clinical, laboratory, and other prognostic factors that influenced treatment outcome. FLT3-ITD mutation was tested by PCR. RESULTS: The frequency of CD135 expression was 138 (53.7%) of 257. FLT3-ITD was detected in (21.4%). Positive CD135 expression was associated with high total leukocyte count (P = .006), platelet count (P = .003), monocytic leukemia (P < .001), and CD34 (P = .008) and CD117 (P = .006) expression. CD135 expression ≥ 25% was a predictor of FLT3-ITD mutation (P = .03). CD135 overexpression was a negative predictor of complete remission and of postinduction minimal residual disease at days 14 and 28 (P < .001). CD135 had an adverse impact on overall and disease-free survival (68.5% vs. 15%, P = .002). Multivariate analysis indicated CD135 was the sole independent prognostic factor for overall survival (hazard ratio = 2.49; 95% confidence interval, 1.855-3.345; P < .001). CONCLUSION: CD135 is emerging as a prognostic factor, a new marker for minimal residual disease, and a potential novel therapeutic target of AML.

Global left ventricular performance in non-diabetic non-hypertensive metabolic syndrome adults.

AIM: To evaluate the left ventricular structure and function in isolated metabolic syndrome. METHODS: One hundred and fifty six consecutive adults with metabolic syndrome were enrolled in the study. Fifty nine had isolated metabolic syndrome (group A) and 97 had metabolic syndrome with hypertension and/or diabetes (group B). There was a control group of 34 healthy adults. In addition to classic echocardiographic assessment of myocardial structural and functional changes, the Tei index was used to evaluate global left ventricular performance. RESULTS: There were no statistically significant differences between group A and controls in all parameters of left ventricular structural, systolic, and diastolic function except global myocardial performance (Tei index). On the other hand, significant differences were observed between group B and the control group in most of the parameters of left ventricular structural and global performance. CONCLUSION: The early identification of isolated metabolic syndrome in non-diabetic, non-hypertensive adults may be an indication that aggressive preventive measures should not be postponed until overt obesity, hypertension or diabetes mellitus has developed.