Averting the legacy of kidney disease-focus on childhood.

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

World Kidney Day 2016: averting the legacy of kidney disease-focus on childhood.

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

El Día Mundial del Rinón 2016 está dedicado a la nefropatía infantil y a los antecedentes de nefropatía adulta que puede comenzar durante la primera niñez. La insuficiencia renal crónica (IRC) pediátrica difiere de la patología en los adultos dado que el principal grupo diagnóstico entre los niños incluye las anomalías congénitas y los trastornos hereditarios, mientras que las glomerulopatías y la nefropatía en el contexto de la diabetes son relativamente infrecuentes. Asimismo, muchos niños con lesión renal aguda tendrán, en última instanci secuelas que podrían derivar en hipertensión e IRC durante el resto de la infancia o la vida adulta. Los niños nacidos prematuros o pequeños para la edad gestacional tienen un riesgo relativamente mayor de desarrollar IRC más adelante. Es necesario supervisar atentamente a las personas nacidas por un parto de alto riesgo y con antecedentes durante la primera infancia para detectar a tiempo los signos tempranos de la nefropatía y así lograr la prevención o el tratamiento eficaces. Es posible tratar la IRC avanzada durante la niñez de forma satisfactoria. Según la evidenci los niños tienen mejor pronóstico que los adultos si reciben tratamiento renal sustitutivo, incluida la diálisis y el trasplante, mientras que solamente una minoría podría necesitar esta última intervención. Dadas las disparidades en el acceso a la atención, se requieren esfuerzos para que los niños con nefropatía puedan recibir un tratamiento eficaz, independientemente de dónde vivan o de las circunstancias geográficas o económicas. Esperamos que el Día Mundial del Rinón brinde información al público en general, a los responsables de formular políticas y a los cuidadores acerca de las necesidades y posibilidades en torno a la nefropatía infantil.

Evitando o legado da doença renal - Foco na infância / Averting the legacy of kidney disease-focus on childhood

Resumo O Dia Mundial do Rim de 2016 estará focado na doença renal na infância e os antecedentes da doença renal no adulto ,que pode começar na mais tenra infância. A doença renal crônica (DRC) na infância é diferente daquela dos adultos, como o maior grupo de diagnóstico entre as crianças inclui anomalias congênitas e doenças hereditárias, com glomerulopatias e doença renal com diabetes sendo relativamente incomum. Além disso, muitas crianças com lesão renal aguda acabarão por desenvolver sequelas que podem levar à hipertensão e doença renal crônica mais tarde na infância ou na idade adulta. As crianças nascidas precoces ou aquelas que nascem pequenas para a idade gestacional têm relativamente maior risco de desenvolver DRC mais tarde na vida. As pessoas com parto de alto risco e história no início da infância devem ser acompanhadas de perto, a fim de se detectar sinais precoces da doença renal em tempo hábil, para submetê-las à prevenção ou tratamento eficaz. O tratamento pode ser bem-sucedido para DRC avançada na infância; há evidência de que as crianças se saem bem melhor do que os adultos, se receberem terapia de substituição renal, incluindo diálise e transplante, enquanto que apenas uma minoria das crianças podem necessitar desse último. Uma vez que existem disparidades no acesso aos cuidados de saúde, é necessário um esforço de modo a que as crianças com doença renal, onde quer que morem, possam ser tratadas de forma eficaz, independentemente das suas circunstâncias geográficas ou econômicas. Nossa esperança é que o Dia Mundial do Rim, leve informação ao público em geral, aos formuladores de políticas públicas e cuidadores sobre as necessidades e possibilidades que cercam a doença renal na infância.

Abstract World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

Día mundial del riñón 2016, evitando el legado de la enfermedad renal, con enfoque en la niñez / World kidney day 2016, "adverting the legacy of kidney disease, focus on childhood

El Día Mundial del Riñón 2016 se enfoca en las enfermedades renales durante la infancia y en los antecedentes de la enfermedad renal del adulto que puede iniciar en la edad temprana. La Enfermedad Renal Crónica (ERC) en la infancia difiere de la de los adultos en que predominan las causas derivadas de anomalías congénitas y trastornos hereditarios, siendo poco frecuentes las glomerulopatías y la enfermedad renal asociada a diabetes. Adicionalmente, muchos niños con Injuria Renal Aguda pueden eventualmente desarrollar secuelas que lleven a hipertensión y ERC durante la adolescencia o la vida adulta. Los niños nacidos prematuros o pequeños para la edad gestacional tienen un incremento del riesgo para desarrollar ERC durante su vida. Personas con alto riesgo al nacer o en la primera infancia, deberán ser monitorizadas estrechamente para ayudar a detectar a tiempo signos tempranos de enfermedad renal a fin de proporcionar una prevención o tratamiento efectivos. Una terapia exitosa es factible para niños con ERC avanzada; existe evidencia que demuestra que los niños evolucionan mejor que los adultos cuando reciben terapia de reemplazo renal, incluyendo diálisis y trasplante, aunque solo una minoría de los niños puede requerir este tratamiento. Debido a las inequidades en el acceso a la atención médica, es necesario hacer un esfuerzo para que los niños con enfermedad renal, donde sea que vivan, puedan ser tratados de manera eficaz, independientemente de su ubicación geográfica y situación y económica. Nuestra esperanza es que el Día Mundial del Riñón pueda informar al público en general, a los tomadores de decisiones y a los profesionales de la salud, sobre las necesidades y las posibilidades que existen alrededor de la enfermedad renal en la infancia

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the lar- gest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood