Examination of the effects of cannabidiol on menstrual-related symptoms.

Some individuals attempt to alleviate menstrual-related symptoms (MRS) by using cannabis and report having expectations that cannabis can improve MRS; however, no study has examined the effect of cannabinoids on MRS. The present study is a pre-post, randomized, open-label trial that aimed to examine the effects of oral cannabidiol (CBD) isolate for alleviating MRS. Participants were assigned randomly to one of two open-label dosing groups of CBD softgels (160 mg twice a day, BID, n = 17; 320 mg BID, n = 16) and completed a 1-month baseline period. Following baseline, participants were instructed to consume CBD starting the first day they believed they experienced symptoms each month and to take their assigned dose daily for 5 consecutive days for three CBD-consumption months. We examined differences in MRS and related outcomes between baseline and 3 months of CBD consumption. Results revealed reductions (in both dosing groups) in MRS, irritability, anxiety, global impression of change, stress, and subjective severity scores when comparing baseline to all 3 months of CBD consumption. Depression scores did not change in either dosing group. Findings suggest that CBD may have the potential for managing MRS. Importantly, changes in symptoms appeared in the first month of CBD consumption and persisted over the 3 consumption months. Further research is warranted comparing the effects of CBD to placebo (a limitation of the study) and examining the potential to optimize CBD consumption for reducing MRS (e.g., combining CBD with terpenes; varying routes and timing of administration). (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Initial Validity Evidence for a Measure of Transactional Sex in a U.S. College Student Sample.

The current study provides initial validity evidence for a measure of Transactional Sex (TS). Participants (N = 269) were recruited from a Northeastern University in the United States and consisted of undergraduate and graduate students. Participants completed an online survey through QuestionPro that contained the Transactional Sex Measure (TSM) as well as measures of depression, anxiety, and stress, condom use negotiation self-efficacy and sexual risk, alcohol and drug use, and materialism. Construct and criterion validity were examined. Findings revealed that the TSM provided good criterion validity evidence but the construct validity evidence was minimal. Further studies on the conceptualization of TS and distribution of the TSM across a variety of diverse samples can provide more validity evidence.

A preliminary investigation of the simultaneous effects of cannabidiol and caffeine.

Caffeine and cannabidiol (CBD) are commonly consumed by the general population, particularly among young adults; however, there is little research on the simultaneous effects of caffeine and CBD. The present study aimed to examine the simultaneous self-reported effects of caffeine and CBD in young healthy adults. Participants (N = 54) who reported daily caffeine use (> 200 mg) attended one experimental session via Zoom and were assigned randomly to receive caffeine (200 mg) combined with either a placebo or CBD (25, 50, 80, 160, or 240 mg). Participants completed subjective drug effects measures at baseline and then ingested caffeine and their assigned CBD dose. Throughout the 140-min session, participants completed self-report measures. The primary outcomes of this study were measures of general drug effects and anxiety. After caffeine and CBD administration, few effects were observed in self-reported measures of general drug effects. No negative effects emerged as a result of combined caffeine and CBD administration. These results should be interpreted cautiously given the preliminary nature and variability in outcomes. The present study findings suggest that combinations of the tested doses of caffeine and CBD do not alter subjective drug effects; further, no negative effects emerged, providing preliminary safety evidence for using these products simultaneously. Further research is needed to examine the simultaneous and/or interactive nature of caffeine and CBD on other caffeine-induced outcomes (e.g., cognition and physiological effects) and will be critical for informing future regulatory decisions regarding caffeine: CBD mixtures. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

A Double-Blind, Randomized, Placebo-Controlled Test of the Effects of Cannabidiol on Experiences of Test Anxiety Among College Students.

Introduction: Oral administration of cannabidiol (CBD) has shown to yield a variety of therapeutic benefits among humans, particularly regarding symptoms of anxiety. This study tested single oral administration doses of CBD (150, 300, or 600 mg), compared to placebo, for reducing test anxiety (TA) in a researcher-derived experimental analog. Method: Our sample included 32 healthy college students who self-reported moderate-to-severe levels of TA. Participants attended an experimental session, and received a dose of CBD or placebo, in a double-blind procedure. After administration of CBD, participants completed a statistics examination and measures of TA and general anxiety during examination administration. Results: Results indicated no effect of CBD dose on self-reported TA or general anxiety; however, results indicated efficacy of our experimental manipulation for inducing TA in vivo. Discussion: This is the first study to demonstrate that CBD does not reduce experiences of TA, and future work may examine the underlying mechanisms and affective states related to anxiety for which CBD may offer anxiolytic benefits, and for whom.

An investigation of the reinforcing value of video game playing relative to concurrently available monetary alternatives.

OBJECTIVE: Video game playing (VGP) has received recent attention as a result of sharing many similarities with other addictive behaviors. Behavioral economic models are commonly used to understand drug use and other addictive behaviors and may similarly inform conceptual models of VGP. METHOD: The present study employed behavioral economic principles to conceptualize relative reinforcing value for playing video games compared to concurrently available alternative potential monetary reinforcers. Participants (N = 81) played three video games picked to represent games of low, medium, and high quality (i.e., OutDrive, Forza Motorsport 1, and Forza Motorsport 7), with quality designations based on the research teams' assessment of various features of the game (e.g., graphics, sound, immersion) as well as the game's market value at the time the study was conducted. Participants played each game for 10 min and completed Visual Analog Scales and a multiple-choice procedure (MCP) designed to assess relative reinforcing value at various time points during and after each session. RESULTS: As hypothesized, both subjective ratings and relative reinforcing value increased as the designated quality of the game increased. More specifically, the high-quality game was rated as more fun and likable and had a higher MCP crossover point than the medium and low-quality games. CONCLUSIONS: Like other behavioral addiction studies, results suggest that methodologies and behavioral measures commonly used in drug administration literature can be effectively applied to VGP. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

The Effects of Alcohol Priming on the Subsequent Value of Alcohol.

OBJECTIVE: Previous research has investigated the effects of substance priming (i.e., substance exposure or preload) on the subsequent value of alcohol. Studies suggest that substance priming may serve as a cue, resulting in increased desire for the substance or drug-related behavior; however, results have been inconsistent. The current studies aimed to examine the effects of a priming dose of alcohol, compared with placebo, on the relative reinforcing effects of subsequent alcohol. METHOD: Undergraduate students (Study 1: N = 46 [33 women]; Study 2: N = 69 [50 women]) completed the Multiple Choice Procedure (MCP) during individual, lab-based sessions. The MCP was used to assess the relative reinforcing value of alcohol compared with concurrently available alternatives. Study 1 compared a standard dose of alcohol (one standard drink) with placebo, and Study 2 compared g/kg dosing of alcohol (controlling for gender) with placebo. RESULTS: Data revealed no statistically significant priming effect of alcohol on the subsequent value of alcohol in either study. CONCLUSIONS: The conditions under which alcohol priming does (and does not) occur are still not fully understood, and further systematic work is necessary to determine potential clinical utility.

Using the Multiple-Choice Procedure to Measure the Relative Reinforcing Efficacy of Gambling: Initial Validity Evidence Among College Students.

The multiple choice procedure (MCP) is used to assess the relative reinforcing value of concurrently available stimuli. The MCP was originally developed to assess the reinforcing value of drugs; the current within-subjects study employed the MCP to assess the reinforcing value of gambling behavior. Participants (N = 323) completed six versions of the MCP that presented hypothetical choices between money to be used while gambling ($10 or $25) versus escalating amounts of guaranteed money available immediately or after delays of either 1 week or 1 month. Results suggest that choices on the MCP are correlated with other measures of gambling behavior, thus providing concurrent validity data for using the MCP to quantify the relative reinforcing value of gambling. The MCP for gambling also displayed sensitivity to reinforcer magnitude and delay effects, which provides evidence of criterion validity. The results are consistent with a behavioral economic model of addiction and suggest that the MCP could be a valid tool for future research on gambling behavior.

Celebrating St. Patrick's Day: Students' Expectations, Intent, and Behavior.

College students engage in risky alcohol use within a variety of contexts, including specific celebratory events. Student intentions and peer perceptions predict alcohol use; however, how these factors affect specific celebratory drinking may vary from typical alcohol use. The current study sought to better understand event-specific drinking among college students during St. Patrick's Day, as compared to Spring Break. Undergraduate students (N = 82) at a campus with a unique traditional celebration of St. Patrick's Day were surveyed. At Time 1, participants were asked to indicate how much alcohol they intended to drink and how much alcohol they expected other students to drink during St. Patrick's Day and Spring Break. At Time 2, students reported on actual alcohol consumption during both events. Results indicated that participants reported greater intent to consume, expectation of peer consumption, and actual alcohol consumption during St. Patrick's Day as compared to Spring Break. Neither sensation seeking nor impulsivity predicted alcohol use during either event. Findings are discussed in the context of understanding, preventing, and intervening with event-specific drinking among college students.

The impact of campus traditions and event-specific drinking.

OBJECTIVE: Specific events (e.g., Spring Break, holidays) are associated with greater college student drinking. However, the ways in which specific events are celebrated at specific campuses may impact students' beliefs about the social acceptability of drinking during these events, which may impact students' event-specific drinking. The present study investigated whether two campuses with different traditions regarding St. Patrick's Day and Mardi Gras differed on event-specific normative beliefs, intent to drink, and actual alcohol consumption. METHOD: Undergraduate students at two campuses (N=570, 59% female) were surveyed pre- and post-events. Campus 1 has specific campus-wide traditions regarding St. Patrick's Day whereas Campus 2 has specific campus-wide traditions regarding Mardi Gras. Prior to the events, participants were asked to indicate how much they expected their peers to drink and how much alcohol they intended to drink themselves during these events. After the events, students reported how much alcohol they actually consumed during the events. RESULTS: Campus 1 reported greater intent to drink and actual drinking during St. Patrick's Day than Campus 2, whereas Campus 2 reported greater intent to drink and actual drinking during Mardi Gras than Campus 1. Campus 1 reported greater norms during SPD than Campus 2, whereas Campus 2 reported greater norms during MG than Campus 1. Event-specific norms did not moderate the relation between event and student event-specific drinking. CONCLUSION: Campuses with different event-specific traditions differed in intent to drink and actual event-specific drinking. Findings have important implications for campus-wide interventions and individual treatment.

Physical activity and cannabis cessation.

BACKGROUND AND OBJECTIVES: Based on recent empirical and theoretical work suggesting that physical activity (PA) activates many of the same physiological systems as cannabis, the present study sought to investigate the impact of PA level (ie, low [including none] vs. moderate/high) on a cannabis cessation attempt during the first 7 days post-quit. METHODS: The present study was a 2 time-point prospective study of 84 cannabis dependent military veterans (3 female) who responded to study flyers, within a Veterans Affairs Medical Center, seeking individuals interested in engaging in a self-guided cessation attempt. All study measures were self-report. RESULTS: Though no baseline differences between those with low and those with moderate/high levels of physical activity were observed, results revealed that participants who reported low levels of physical activity, versus moderate/high levels, were significantly more likely to report a cannabis lapse during the week following a quit attempt, particularly within the first 4 days of the cessation period. Further, individuals with low levels of PA were also more likely to report greater mean cannabis use during the first 4 days of the cessation period. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Findings suggest that early interventions aimed at increasing physical activity may be useful among individuals with cannabis dependence who are engaged in a cessation attempt.

Tobacco use among African-American youth receiving behavioral healthcare services.

African-American youth with behavioral health problems may be particularly vulnerable to tobacco use and dependence; however, little is known about overall prevalence and factors associated with tobacco use in this population. The present study compared rates of tobacco use for African-Americans (aged 13-17) receiving behavioral healthcare services to state and national prevalence rates. In addition, we examined whether tobacco use prevalence was related to treatment characteristics and services rendered. Retrospective chart reviews were conducted at an urban, public behavioral healthcare agency for youth admitted in 2009. Tobacco use rates among African-Americans receiving behavioral healthcare services were similar to, and in some cases, higher than statewide and national prevalence rates. While tobacco users were more likely to be enrolled in a substance abuse program than in a mental health program, only 2 of 55 youth reporting tobacco use had received documented tobacco cessation treatment. Future work should focus on implementing tobacco cessation prevention and treatment for these youth.

Relationship between Facebook use and problematic Internet use among college students.

The popularity of Facebook and other online social-networking sites has led to research on the potential risks of use, including Internet addiction. Previous studies have reported that between 8 percent and 50 percent of college students report problems consistent with Internet addiction. The current study assessed a range of variables related to Facebook use, and sought to determine how the use of Facebook relates to problematic Internet use. Undergraduate participants (N=281, 72 percent women) completed a battery of self-report measures, including the Internet Addiction Test, via an online interface. The results of the current study suggest that a sizable minority of students experience problems related to Internet use and that the use of Facebook may contribute to the severity of symptoms associated with Internet addiction.

The reinforcing value of alcohol in a drinking to cope paradigm.

BACKGROUND: Alcohol use is often regarded as a means of coping with sadness and distress. The present research was conducted to explore the relation between negative mood and the reinforcing value of alcohol, while clarifying the role of coping motives. METHODS: Participants with a history of recent alcohol use (N=44; 72% female) attended a laboratory session and were randomly assigned to either a negative (n=22) or a neutral (n=22) mood condition. A manipulation check confirmed that participants in the negative mood condition, but not the neutral mood condition, displayed a significant increase in negative affect. The multiple choice procedure (MCP) was used to measure the reinforcing value of alcohol after the mood manipulation. RESULTS: Regression models employing the MCP crossover point as the dependent variable and mood condition (neutral or negative) and drinking to cope as predictors indicated that a model with an interaction term accounted for the most variance. CONCLUSIONS: These results suggest that the relation between mood and the reinforcing value of alcohol is moderated by drinking to cope, and help clarify the conditions under which drinking to cope may lead to negative outcomes.

Anxiety sensitivity as a mediator of the relationship between moderate-intensity exercise and coping-oriented marijuana use motives.

The present study examined the working hypothesis that moderate-intensity exercise is associated with coping-oriented marijuana use motives through its association with the fear of somatic arousal (ie, anxiety sensitivity). Using data from 146 young adult current marijuana users, we found evidence consistent with this hypothesis. Specifically, moderate-intensity exercise was associated with coping-oriented use motives, even after controlling for frequency of current marijuana use and other co-occurring marijuana use motives. This relationship became nonsignificant after entering anxiety sensitivity as an additional predictor variable, denoting a putative mediational role for this cognitive factor. These findings extend previous work and offer support for the potential utility of moderate-intensity aerobic exercise for the treatment of marijuana use problems.

Exercise and coping-oriented alcohol use among a trauma-exposed sample.

The present investigation examined the relation between exercise intensity and alcohol use coping motives among trauma-exposed adults. Participants were 114 adults (58 women; M(age)=22.31 years, SD=8.89) who reported exposure to at least one traumatic event (American Psychiatric Association, 2000) and alcohol use in the past 30 days. Partially consistent with expectation, engagement in vigorous-intensity activities (≥6 resting metabolic rate [MET] score) demonstrated a significant, incremental (negative) association with alcohol use coping motives. This incremental association was observed after accounting for current alcohol consumption, non-criterion alcohol use motives, anxiety sensitivity, posttraumatic stress symptom severity, as well as engagement in light- and moderate-intensity activities (<6 resting MET score). Results are discussed in terms of better understanding the association between vigorous-intensity aerobic exercise and coping-oriented alcohol use among trauma-exposed individuals.

A brief abstinence test for college student smokers: a feasibility study.

Cigarette smoking among college students is prevalent and correlated with other unhealthy behaviors. Reinforced abstinence (e.g., contingency management) has been demonstrated to be an effective method for reducing substance use in a variety of populations and across a variety of drugs, including cigarettes. Reinforced abstinence has seldom been used specifically targeting a college student population. A Brief Abstinence Test (BAT) has been used to effectively reduce cocaine use among methadone maintenance patients (Robles, Silverman, Preston, Cone, Katz, Bigelow, & Stitzer, 2000). However, no published studies have investigated the use of a BAT to reduce the use of cigarettes. The current study implemented a 3-week intervention (Baseline 1, BAT, and Baseline 2 weeks) for smoking abstinence among college students. Forty-two percent of the sample met abstention criteria during the BAT. Carbon monoxide and urinalysis scores decreased significantly from Baseline 1 to the BAT phase but did not differ significantly from BAT to Baseline 2. These results suggest that the BAT may have utility initiating abstinence in both clinical and research contexts.

Perceived consequences of cigarette use among college students.

The current study was designed to investigate the perceived consequences of cigarette smoking among a sample of college students. Participants (N=206) rated the negative consequences of smoking higher than the positive consequences on both the Decisional Balance Measure and the Smoking Consequences Questionnaire. While scales assessing the perceived positive consequences of cigarette smoking varied as a function of smoking status, the perceived negative consequences of smoking did not vary as a function of smoking status or stage of change. This pattern of findings is inconsistent with previous studies, which have reported that the relationship between the perceived positive and negative consequences of smoking shifts towards a more negative view as smokers become more motivated to change or actually quit smoking. The differential patterns of results across studies highlight the need for continued research on the relationship between the perceived consequences of cigarette use and actual smoking behavior among young adults who smoke but are not necessarily nicotine dependent.

Using national alcohol screening day to deliver personalized feedback: a pilot study.

The current study tested the effectiveness of using National Alcohol Screening Day (NASD) to deliver personalized feedback via mail. At-risk NASD participants were assigned to either personalized or generic feedback conditions and attended a 4-week follow-up. Results failed to find any group differences on alcohol-related variables. However, participants in the personalized group reported a reduction in the maximum number of drinks consumed on one occasion. The personalized group also had a more accurate view of the amount of alcohol their peers consumed. NASD is a vehicle to efficiently deliver feedback to individuals about their alcohol use; however, more research is needed to determine the types of feedback that would be most effective.