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1.
Eisei Shikenjo Hokoku ; (114): 48-9, 1996.
Artigo em Japonês | MEDLINE | ID: mdl-9037865

RESUMO

Preliminary screening of antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 138 samples tested, two were found to inhibit the growth of HIV in vitro. Neither of the positive samples has hopeful signs, as the ranges of effective doses of the samples are very narrow.


Assuntos
Fármacos Anti-HIV/farmacologia , HIV-1/efeitos dos fármacos , Avaliação Pré-Clínica de Medicamentos/métodos , Resistência Microbiana a Medicamentos , Testes de Sensibilidade Microbiana/métodos
2.
Eisei Shikenjo Hokoku ; (114): 50-2, 1996.
Artigo em Japonês | MEDLINE | ID: mdl-9037866

RESUMO

Preliminary screening of antiviral AIDS drugs has been carried out using three different in vitro assay systems. Among 246 samples of different origin tested, six were shown to inhibit the growth of HIV in vitro. Two of the positive samples have hopeful signs, as the ranges of effective doses are wider than those of most of positive samples which had been found by us.


Assuntos
Fármacos Anti-HIV/farmacologia , HIV-1/efeitos dos fármacos , Avaliação Pré-Clínica de Medicamentos/métodos , Resistência Microbiana a Medicamentos , Testes de Sensibilidade Microbiana/métodos
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