Exploring the antioxidant and antimicrobial potential of three common seaweeds of Saint Martin's Island of Bangladesh.

Antioxidants, which have long been deemed an indispensable guardian of human health, play a pivotal role in bolstering the body's defense against a plethora of diseases. Three well-recognized seaweeds in Bangladesh, including Caulerpa racemosa, Padina tetrastromatica, and Hypnea musciformis, were subjected to meticulous analysis to reveal their phytochemical composition, antioxidant activity, and antimicrobial efficacy using advanced spectroscopic and disc diffusion methods. Intriguingly, we observed that C. racemosa emerges as frontrunners, possessing a substantial arsenal of phenol (143.08 ± 18.51 mg gallic acid equivalent g─1) and flavonoid (63.79 ± 2.16 mg rutin equivalent g─1). More fundamentally, C. racemosa exhibits a notable enrichment in the content of tannin (73.58 mg RE g─1) and chlorophyll (13.50 mg g─1), as well as, antioxidant capacity (4457.67 µg g─1). P. tetrastromatica, on the other hand, displayed commendable effectiveness in scavenging the DPPH radical, with percentages ranging from 53.98 to 62.17%. In terms of hydroxyl radical (OH•) scavenging activity, C. racemosa exhibited the highest efficacy at 400 g mL─1. Fascinatingly, C. racemosa exhibited an impressive antioxidant potential, as evidenced by its exceptionally low IC50 value of 5.58 µg mL-1 for OH• scavenging, whereas P. tetrastromatica showed impressively low value of 0.96 µg mL-1 for DPPH scavenging. Although the three seaweeds demonstrated limited efficacy against a spectrum of five human pathogenic bacteria, their potential as abundant sources of antioxidants remains unscathed. Notably, heatmap and PCA analysis revealed that C. racemosa and P. tetrastromatica emerge as the leading contender for studied antioxidant compounds, demonstrating their proclivity for antioxidant extraction, a trait that could be exploited for large-scale production of these valuable compounds.

Racial Variation of Carrying Angle of Elbow in North-East Indian Population: A Clinico-Radiological Study.

BACKGROUND: Carrying angle of elbow is the angle borne by the forearm to the arm in fully extended elbow and supinated forearm. Northeast Indian population being an amalgamation of diverse ethnicity of population, the researchers have felt the necessity of a reference value for this anthropometric parameter for pre-operative planning and template. The objective is to study the difference in carrying angle between males and females and its correlation with different parameters like age, sex, height, body mass index and handedness. MATERIALS AND METHODS: The study was conducted in Gauhati Medical College and Hospital on 384 persons with ages ranging from 20 to 74 years. Carrying angle was measured by goniometer and confirmed by radiography. RESULTS: Three hundred and forty-three were right handed while 41 individuals were left handed. In males, the mean carrying angle of the right elbow was found to be 12.55 ± 2.3° and of the left was found to be 12.27 ± 2.43°, while in females, the mean carrying angle of the right elbow was found to be 14.53 ± 2.34° and 14.06 ± 3.37° in the left (p < 0.05). Carrying angle is usually found significantly higher in dominant upper limb. There is no significant difference in carrying angle for northeast Indian population from the rest of the country. CONCLUSION: We have found that carrying angle is dependent on gender and on dominance of upper limb. The carrying angle variation in Northeastern Indian population is almost comparable with the population of the rest of our country except for some specific tribes which needs further analysis.

Analysis of biliary anatomy according to different classification systems.

PURPOSE: Variations in biliary anatomy are common, and different classifications have been described. These classification systems have not been compared to each other in a single cohort. We report such variations in biliary anatomy on magnetic resonance cholangiopancreatography (MRCP) using six different classification systems. METHODS: In 299 patients undergoing MRCP for various indications, biliary anatomy was classified as described by Couinaud (1957), Huang (1996), Karakas (2008), Choi (2003), Champetier (1994), and Ohkubo (2004). Correlation with direct cholangiography and vascular anatomy was done. Bile duct dimensions were measured. Cystic duct junction and pancreaticobiliary ductal junction (PBDJ) were classified. RESULTS: Normal biliary anatomy was noted in 57.8 %. The most common variants were Couinaud type D2, Choi type 3A, Huang type A1, Champetier type a, Ohkubo types D and J, and Karakas type 2a. The Ohkubo classification was the most appropriate; 3.1 % of right ducts and 6.3 % of left ducts with variant anatomy could not be classified using the Ohkubo classification. There was a good agreement between MRCP and direct cholangiography (ĸ = 0.9). Anomalous PBDJ was noted in 8.7 %. Variant biliary anatomy was not associated with gender (p = 0.194) or variant vascular anatomy (p = 0.24). CONCLUSION: Although each classification system has its merits and demerits, some anatomical variations cannot be classified using any of the previously described classifications. The Ohkubo classification system is the most applicable as it considers most clinically relevant variations pertinent to hepatobiliary surgery.

Non-bleeding Spontaneous Rupture of Hepatocellular Carcinoma.

Rupture of hepatocellular carcinoma (HCC) is not uncommon and most ruptured HCC present with hemoperitoneum and hemorrhagic shock. Management of ruptured HCC is different than non-ruptured one. Short- and long-term mortality increases following rupture of HCC with increasing chances of tumor dissemination. We describe a case with non-bleeding spontaneous rupture of HCC. A 62-year-old male patient was admitted to our institute hospital with mild to moderate pain in the right upper part of the abdomen. He lost appetite and weight. Ultrasonography of the abdomen was performed and it suggested HCC and ascites. Triple phase computer tomography revealed HCC in segments 6 and 7 of liver with typical radiological characteristics. Portal vein was thrombosed. No extravasation of dye was seen. Ruptured of tumor through liver capsule was seen with necrosis and hemorrhage in the center of the tumor. Non-bleeding ruptured HCC has not been reported in the literature to the best of our knowledge. We herein describe this rare case.