Effects of a 6-month self-rehabilitation programme in addition to botulinum toxin injections and conventional physiotherapy on limitations of patients with spastic hemiparesis following stroke (ADJU-TOX): protocol study for a randomised controlled, investigator blinded study.

INTRODUCTION: Home-based self-rehabilitation programmes combined with botulinum toxin injections (BTIs) appear to be a relevant approach to increase the recommended intensive rehabilitation of patients with spasticity following a stroke. The literature highlights a lack of evidence of beneficial effects of this adjuvant therapy to reduce limitations of patients with stroke. The aim of this study is to assess the effects of a 6-month self-rehabilitation programme in adjunction to BTI, in comparison with BTI alone, to reduce limitations of patients with spasticity following a stroke. METHODS AND ANALYSIS: 220 chronic patients will participate to this multicentre, prospective, randomised, controlled, assessor blinded study. All patients will benefit from two successive BTI (3 months apart), and patients randomised in the self-rehabilitation group will perform in adjunction 6 months of self-rehabilitation at home. All patients continue their conventional physiotherapy. The main outcome is the primary treatment goal (PTG), which will be determined jointly by the patient and the medical doctor using Goal Attainment Scaling. Impairments and functions, quality of life, mood and fatigue will be assessed. Botulinum toxin will be injected into the relevant muscles according to the PTG. Patients in the self-rehab group will be taught the self-rehabilitation programme involving respectively 10 min of stretching, 10 min of strengthening and 10 min of task-oriented exercises, corresponding to their PTG. Compliance to the self-rehabilitation programme will be monitored. ETHICS AND DISSEMINATION: Patients will sign written informed consent. Ethical approval was obtained from ethics committee. The results will be disseminated in a peer-reviewed journal and presented at international congresses. The results will also be disseminated to patients. TRIAL REGISTRATION NUMBER: NCT02944929.

Braun's flexor tendons transfer in disabled hands by central nervous system lesions.

INTRODUCTION: Since Braun's article, the nonfunctional hand of brain-injured patients has not been the subject of many publications. The objective of surgical treatment is to open the hand for hygiene and cosmetic reasons. The technique consists in lengthening the extrinsic flexor tendons group. HYPOTHESIS: The purpose of this work is to assess eventual functional benefits from superficialis-to-profundus tendon transfer according to Braun. MATERIAL AND METHODS: Our series comprised 15 patients aged a mean 55 years, operated using the Braun procedure for a nonfunctional hand (19 hands). Additional procedures were performed as required by the local condition (neurotomy of the deep branch of the ulnar nerve, wrist fusion, tenotomy of the flexors of the wrist and flexor pollicis longus, tenodesis of the extensors of the wrist). The results were assessed by the analysis of finger opening ability and by a specific scoring system (Mini Hand Score; MHS) rated from 6 (no discomfort) at 20 (major discomfort). RESULTS: The mean follow-up was 6 months. We observed imperfect results: thumb opening incapacity, spasticity of the intrinsic flexors, and hyperextension of the wrist. The preoperative MHS was a mean 13.87 out of 20 and the postoperative MHS was 9.67 out of 20, with a very substantial difference. DISCUSSION: Our easy-to-use system for evaluating the nonfunctional hand (MHS) was shown to be very effective in demonstrating the improvement of the postoperative result. The originality of our series was to show that Braun's original operation goals were only exceptionally and remotely achieved and that an additional technical procedure must be nearly systematically considered. All the patients in our series were followed up in multidisciplinary team visits where the patient's family and caretakers were encouraged to give their point of view. Level of evidence Level IV. Retrospective study.

[A rare cause of constipation: neurinoma of the fourth lumbar nerve. Case report and review of the literature ]. / Une cause rare de constipation: le neurinome du quatrième nerf lombaire. A propos d'un cas et revue de la littérature.

Constipation is a symptom not to be neglected, especially if the complaint is recent. We report a case where this symptom was the only clinical manifestation of a voluminous retroperitoneal tumor. The tumor was found to be a neurilemmoma of the fourth right lumbar roots, confirmed at pathological examination. Manifestations of extradural neurinomas generally result from compression of neighboring structures. The best preoperative diagnosis approach is magnetic resonance imaging but histology is required for confirmation. The close relations the tumor mass maintains with the unaffected nerve fibers makes resection difficult without postoperative functional consequences. Surgeons discuss the relevance of partial excision in order to preserve the nerve root in case of a benign slow-growing tumor. There does however appear to be a significant recovery of muscle strength even in case of total resection.