The clinical effect of experimental infection with Trypanosoma congolense on Dutch belted rabbits.

The clinical effect of Trypanosoma congolense infection on Dutch belted (does) rabbits was investigated. Sixteen Dutch belted rabbits weighing between 1.6 and 1.8 kg were grouped into two groups of eight each. Animals were accessed for packed cell volume (PCV), total leucocyte count (TLC), rectal temperature (RT), heart rate (HR), and body weight (BW) before infection as well as 18, 25, and 58 days post inoculation (PI). The level of parasitaemia was estimated on a weekly basis and was graded by number of parasites/field. There was a significant difference (P < 0.05) in the mean PCV between treatment and control groups of the rabbits on all days PI. The other parameters were not significantly different between uninfected controls and treatment group although the rectal temperature fluctuated. The mean PCV of infected rabbits was 36.0 ± 0.53%, 35.3 ± 0.19%, and 28.0 ± 0.89% at days 18, 25, and 58 PI, while for uninfected, the mean PCV was 40.8 ± 0.11%, 41.8 ± 0.19%, and 41.3 ± 0.08% across the same time periods. Parasitaemia was detected at 6th day PI and remained high to the end of the study. The study suggests that the use of haematinics and anti-pyrexia treatments as part of disease management for rabbits would be useful.

Azanza garckeana ameliorates Bisphenol A-induced reproductive toxicities in rabbit bucks.

This study evaluated the ameliorative properties of Azanza garckeana in Bisphenol A-induced reproductive toxicities on weight, spermiogram, serum hormonal profile, sperm DNA integrity, histopathology of testes and brain tissues of rabbit bucks. Twenty-eight rabbit bucks, with live weight of 1.20-2.00 kg and aged 10-18 months. They were randomly divided into four groups of seven bucks each, group A was administered distilled water (1.5 mL) daily for 12 weeks, group B was administered Bisphenol A (100 mg/kg) for 5 consecutive days in a week for a period of 12 weeks, group C was administered Azanza garckeana (500 mg/kg) daily for 12 weeks and group D was pre-dosed with Bisphenol A (100 mg/kg) for 5 consecutive days in a week over 6 weeks period followed by Azanza garckeana (500 mg/kg) daily for another 6 weeks. Mean testicular weights differed significantly (p < 0.05) between group B (4.4 ± 0.23) when compared with groups A (8.0 ± 0.06), C (8.7 ± 0.19) and D (7.1 ± 0.18). There were significant differences (p < 0.05) in the mean reaction time, spermiogram, testosterone, follicle stimulating hormone, luteinising hormone and sperm DNA fragmentation index between Bisphenol A-exposed groups and treatment groups. On histopathology, there was testicular vacuolization, interstitial hemorrhage, reduction in spermatogenic cells following Bisphenol A exposure. There were layers of dense basophilic cells in the pineal and pituitary parenchymas. In conclusion, Bisphenol A has negative effects on reproduction but administration of Azanza garckeana may possess some therapeutic properties that can ameliorate such adverse effects.

Genital lesions in cows naturally infected with trypanosomes in Abuja, Nigeria.

BACKGROUND AND AIM: Different species of trypanosomes have been reported to cause varying degrees of reproductive disorders in pregnant and non-pregnant animals under experimental infections. Information on reproductive disorders and losses in animals naturally infected with trypanosome species are few. This study was carried out to assess the abnormalities in the genital organs (ovaries, oviduct, uterus, cervix, and vagina) of female cattle naturally infected with trypanosomes in and around Abuja, Nigeria. MATERIALS AND METHODS: Cows showing signs such as emaciation, weakness, or anemia were selected and examined at Gwagwalada and Karu abattoirs, respectively. Venous blood samples were taken from 108 of such animals and screened using standard trypanosome detection methods. The genital organs were also collected and inspected for gross and histopathological lesions in the laboratory. RESULTS: Six (5.55%) out of the 108 animals were positive for trypanosomes; 4 (66.7%) were infected with Trypanosoma vivax and 2 (33.3%) were infected with Trypanosoma congolense. The mean packed cell volume of the infected animals was 22.83%. Grossly, congestion and ecchymotic hemorrhages were observed in the endometrium, myometrium, and cervical submucosa. Mucometra, hydrometra, and pyometra were also seen in the uterus. Histologically, necrosis of the epithelium and endometrial glands accompanied by mononuclear cellular infiltration was observed in the uterus. There was also sloughing of the endometrial epithelium, vascular congestion, and hypertrophy of serosa of the uterus. There was atropy of the granulosa cells, increased numbers of degenerating tertiary follicles, and absence of corpora lutea in the ovary. No gross or histopathological lesions were observed in the fallopian tube and vagina. CONCLUSION: The lesions observed were restricted to the uterus and ovary of the animals and were less severe when compared to lesions observed under experimental conditions as reported by previous authors.

Reproductive performance of pigs raised by intensive management system in Abuja, Nigeria.

BACKGROUND: Population growth led to an increase in the number of people raising pigs, resulting in increased demand for piglets/pigs for breeding and pork for consumption. AIM: This study was carried out to determine the reproductive performance of pigs raised by the intensive management system in Abuja, Nigeria, with a view to assist farmers in ensuring improved productivity and profitability. MATERIALS AND METHODS: Using an interview-based questionnaire, data from 121 sows and 649 preweaning piglets were collected in 12 herds, from September 2017 to March 2018. Measures of reproductive and production performance assessed in this study were interfarrowing interval (IFI), number of liveborn piglets (NLB), preweaning piglet mortality (PPM), age at weaning (AAW), weaning to service interval (WSI), age at first farrowing (AFF), number of piglets weaned per litter (NPWL), and number of piglets weaned per sow per year (NPWPY). RESULTS: The results obtained in this study were IFI 6.2±0.84 months, NLB 7.2±1.11, PPM 31%, AAW 40.2±3.12 days, NPWL 5.3±0.73, WSI 39.4±4.59 days, AFF 9.1±0.60 months, and NPWPY 8.1±1.21. The identified causes of PPM were maternal overlay 31.34%, splay leg/hypoglycemia 22.39%, cannibalism 20.40%, starvation 14.93%, and unknown cause 10.94%. CONCLUSION: The result showed that the reproductive performance of the sow (especially, NPWPY and PPM) needs to be improved on. There is a need to promote extension and herd health services by veterinarians and livestock personnel to potential and existing farmers in the area. This is more so because organized pig production in the studied area is relatively new and more people are establishing pig farms in the studied area.