[Immune shifts and their correction in the extremely severe course of diffuse suppurative peritonitis in children]. / Immunnye sdvigi i ikh korrektsiia pri kraine tiazhelom techenii razlichnogo gnoinogo peritonita u detei.

Clinical and immunological studies of 65 patients with extremely severe disseminated suppurative peritonitis have revealed profound disturbances in their immune status. A considerable (2.5-3-fold) decrease in phagocytosis and complement activity, a drastic drop in T-, B-lymphocyte and T-helper content and a depression in T-lymphocyte functional activity have been observed. All this was accompanied by the activation of allergic and autoimmune reactions. Single transfusion of extracorporally X-ray-irradiated autoblood (5-7% of circulating blood volume) promoted an earlier normalization of the patients' critical condition and a prompt correction of the immune shifts.

[Ways of increasing the efficacy of antibiotic therapy in young children with severe forms of acute pneumonia]. / Puti povysheniia éffektivnosti antibiotikoterapii pri tiazhelykh formakh ostroi pnevmonii u detei rannego vozrasta.

Examination of 136 children with the severe form of acute pneumonia treated in a resuscitation unit revealed a marked suppression of the immunity and lowered antibiotic sensitivity of the bacterial microflora isolated from the respiratory tracts. The patients were previously treated with antibiotics of 2 to 5 families. Auto-blood irradiated with X-rays without the host was transfused to 72 children (group 1) with immunomodulating purposes. 64 children (group 2) were treated with the same purposes with eleuterococcus, pentoxyl and methyluracil. After transfusion of the auto-blood irradiated with x-rays without the host there was an increase in the antibiotic sensitivity of the bacterial flora along with a marked and rapid improvement of the immunity status. The severe state was alleviated earlier in the patients of group 1. The inflammatory lesions in the lungs of the group 1 patients were arrested sooner and the patients were discharged from the hospital 11 days earlier than the children treated with the routine immunomodulators.

[The effect of in vitro X-irradiated blood transfusions on the morphostructure of immunocompetent organs and their nerve elements]. / Vliianie transfuzii rentgenoobluchennoi vne organizma krovi na morfostruktury immunokompetentnykh organov i ikh nervnye élementy.

A study was made of changes that occur in the rat thymus, spleen, lymph nodes, their nerve elements, and spinal ganglia under the effect of the in vitro X-irradiated blood transfusions. Parallelism was noted in the activation of the immunocompetent organ morphostructures, the rate of reactive alterations in nerve elements, and the improvement of the immunity indices.

[Intensive and immunocorrective therapy of critical conditions in young children with acute toxic pneumonia with obstructive syndrome]. / Intensivnaia i immunokorrigiruiushchaia terapiia kriticheskikh sostoianii pri ostrykh toksicheskikh pnevmoniiakh s obstruktivnym sindromom u detei rannego vozrasta.

The paper is concerned with an analysis of the data on the immune status in associated fairly grave pneumonia and the obstructive syndrome in 78 infants treated at the resuscitation department. Gross chances were revealed in nonspecific resistance and in the status of the cellular component of immunity. The use in the treatment of a single transfusion of autologous blood x-rayed outside the body promoted the patients' rapid egress from the critical condition as well as the early improvement of the immune system status.

[Clinico-immunological indices, lipid peroxidation and contents of middle mass molecules in young children with different course of suppurative diseases of the lungs and pleura]. / Kliniko-immunologicheskie pokazateli, perekisnoe okislenie lipidov i soderzhanie molekul srednei massy u detei rannego vozrasta s razlichnym techeniem gnoinykh zabolevanii legkikh i plevry.

The results of examination of 83 children with purulent diseases of the lungs and pleura at the age under 6 yrs are presented. The indices of activity of the immunity, intensity of the processes of peroxide oxidation of the lipids, and level of the middle mass molecules were studied. The correlative relationship between them depending on the severity of the course of the disease was revealed.

[Changes in the neural elements of lymphangiomas in children of various ages]. / Izmeneniia nervnykh élementov limfangiom u detei razlichnogo vozrasta.

The results of neurohistologic investigation of lymphangiomas, removed in 68 children, are presented. At the early age in children, the changes in neural fibers of lymphangiomas correspond to reaction of irritation. With increasing of the age, the pronouncement of the destructive processes in the neural fibers increases, leading to hypo- and anervia of the tissues of lymphangiomas.

[Hemangiomas of the skin in children]. / O gemangiomakh kozhnogo pokrova u detei

In the article the indications to and results of surgical treatment of 2420 children with skin hemangiomas are discussed. An operative excision of hemangiomas was used in 1139 cases, electrocoagulation--in 1648, sclerosing therapy--in 21, combined treatment--in 4. In 5 children hemangiomas were removed with subsequent free skin graft plasty. Late results were followed up in 795 (32.8%) children within the terms from 4 months to 10 years, following the excision--in 348 cases and after electrocoagulation--in 447.

[The state of the neural apparatus of cutaneous hemangiomas in children of different ages]. / Sostoianie nervnogo apparata gemangiom kozhi u detei v razlichnye vozrastnye periody

The work was undertaken to study the innervation of 120 skin hemangiomas in children aged from 1 month to 14 years. The data obtained have made it possible to conclude that shifts occurring in hemangioma are manifested by alterations in its nervous apparatus. The growth of hemangioma is accompanied with its hyperneuria, a delay in the tumor growth, its involution - by nerve destruction up to the state of hypo- and aneuria.