[The hemostatic system in patients with pulmonary tuberculosis during their preparation for surgery]. / Sistema gemostaza u bol'nykh tuberkulezom legkikh v period ikh podgotovki k operatsii.

The basic mechanisms responsible for equilibrium impairment in the hemostatic system in pulmonary tuberculosis patients are reduced activity of antithrombin III and disturbances of platelet functional capacities. These changes were proved to reflect the course of intravascular hemocoagulation whose degree of manifestation is related directly to the extent of specific lesions in the lungs and intoxication phenomena. The process of intravascular hemocoagulation in tuberculosis patients runs in the presence of an increased concentration of plasma fibronectin , while major surgery performed in patients with fibrous-cavernous processes leads to its reduced level. It is pathogenetically proved to use antithrombin III concentrate preparations with anti- and dysaggregatory properties, fibronectin preparations, trasylol or its analogs during complex preoperative preparation of patients.

[The use of a concentrate of antithrombin III and disaggregants in the preoperative preparation of patients with pulmonary tuberculosis]. / Primenenie kontsentrata antitrombina III i dezagregantov v predoperatsionnoi podgotovke bol'nykh tuberkulezom legkikh.

A study of the blood coagulation system in 32 patients with pulmonary tuberculosis before surgical intervention showed that reduction of the antithrombine III activity and related enhancement of the thrombin formation reaction and suppression of deaggregation capacities of thrombocytes reflect the latent process of pathological intravascular blood coagulation. The authors suggest justification of restoring the reduced antithrombine blood capacitance and normalization of the deaggregation capacity of thrombocytes by means of the antithrombine III concentrate and disaggregants in the complex preoperative care.

[Functional activity of thrombocytes in patients with post-tuberculosis spinal osteochondrosis complicated by pain syndrome]. / Funktsional'naia aktivnost' trombotsitov u bol'nykh posttuberkuleznym osteokhondrozom pozvonochnika, oslozhnennym bolevym sindromom.

It was found that in patients with attenuated tuberculous spondylitis and post-tuberculous vertebral osteochondrosis there was a sharp increase in platelet aggregability and a decrease in their disaggregability at the peak of the pain syndrome. With the therapy followed by relief of the pain syndrome, a rise in the platelet aggregability was significantly less noticeable, without significant changes in their disaggregability.

[Blood coagulation function in pulmonary tuberculosis patients at the stages of surgical treatment]. / Sostoianie gemokoaguliatsii u bol'nykh tuberkulezom legkikh na étapakh khirurgicheskogo lecheniia.

The results of studying the coagulative properties of blood in 25 patients with pulmonary tuberculosis before surgical operations and at the stages of the postoperative period are presented. It was shown that, unlike the patients mainly with processes of productive nature and insignificant extent of the specific process, the patients with extended fibrocavernous tuberculosis of the lungs even before the operations were characterized by markedly increased thrombin formation. During surgical operations the hemocoagulation impairments in such patients could be aggravated up to development of coagulopathy.