Chemiluminescence as a method for detection and study of free radicals in biological systems.

Chemiluminescence observed during LPO or reactions of nitric oxide and oxygen radicals and was named "ultraweak luminescence". In the presence of chemiluminescence activators (luminol, lucigenin, rhodamine G, or coumarine C-525) the appearance of radicals is associated with intensive fluorescence; the registration of this fluorescence is widely used in biomedical and clinical studies.