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1.
Rozhl Chir ; 101(11): 525-529, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36717259

RESUMO

The use of silicone and latex drains is an integral part of surgical practice. Experience and the review of the world literature show that silicone drain is characterized by a much lower rate of fibrotic reaction of the tissue around the drain. The ability of a latex, or rubber, or popularly called rubber drain, to induce the formation of ligaments in its surroundings is advantageously used in situations where the targeted formation of scar tissue is desired. This feature is absent in silicone drains. However, nowadays the rule in most surgical departments is to use almost exclusively silicone drains, which is based on prevention of latex allergy. This article is devoted to the description of the different and mutually irreplaceable use of silicone and latex drains. Subsequently, he also discusses the question of whether the twilight of the use of latex drains in modern medicine is really progress, or rather retrogression.


Assuntos
Drenagem , Látex , Borracha , Silicones , Humanos
2.
Rozhl Chir ; 93(3): 139-42, 2014 Mar.
Artigo em Tcheco | MEDLINE | ID: mdl-24720717

RESUMO

INTRODUCTION: Diabetic foot syndrome is defined by ulcer or destruction of leg tissues in patients with diabetes (diabetics) associated with infection, neuropathy and various degree of ischaemia (peripheral vascular disease). In Czech Republic in 2010 were registrated over 45 000 patients with diabetic foot syndrome. 8500 (diabetics) patients with diabetes undergone the surgery (any type of amputation). MATERIAL AND METHODS: In retrospective non randomized trial we evaluated the population of patients with lower limb amputation admitted to Clinic of Surgery FNO between 2010-1012. We introduce current (present) view to possibilities of lower limb amputations, historical problems and development of surgical methods. Special aspect is dedicated to sagital shank amputation. Detail description of operative (surgical) technique itself and crural region (area) anatomy. RESULTS: In 2010-2012 we achieved 146 lower limb amputations in shank, from that 27 sagital shank amputations( sagital operative method). We observed ( followed up) the number of reoperations, reasons that led to amputation, wounds healing by secondary intention, ites sources and necessity of revision due to postoperative hemorrhage. CONCLUSION: Effects of amputations on patientes quality of life. Social and socioeconomical impacts. Provably lower number of complications in sagital shank amputations compared to (in comparison with) conventional methods. Authors would like to point out and introduce interesting operation method to the general public.


Assuntos
Amputação Cirúrgica/métodos , Pé Diabético/cirurgia , Complicações Pós-Operatórias/etiologia , Qualidade de Vida/psicologia , Retalhos Cirúrgicos/cirurgia , Amputação Cirúrgica/estatística & dados numéricos , República Tcheca/epidemiologia , Pé Diabético/epidemiologia , Humanos , Complicações Pós-Operatórias/epidemiologia , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Retalhos Cirúrgicos/estatística & dados numéricos , Tíbia/cirurgia
3.
Cell Transplant ; 19(11): 1413-24, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20529449

RESUMO

Fifty percent of diabetics (7% of general population) suffer from peripheral arterial occlusive disease, which may lead to amputation due to critical limb ischemia (CLI). The aim of our study was to prevent major limb amputation (MLA) in this group of patients using a local application of autologous bone marrow stem cells (ABMSC) concentrate. A total of 96 patients with CLI and foot ulcer (FU) were randomized into groups I and II. Patients in group I (n = 42, 36 males, 6 females, 66.2 ± 10.6 years) underwent local treatment with ABMSC while those in group II (n = 54, control, 42 males, 12 females, 64.1 ± 8.6 years) received standard medical care. The frequency of major limb amputation in groups I and II was 21% and 44% within the 120 days of follow up, respectively (p < 0.05). Only in salvaged limbs of group I both toe pressure and toe brachial index increased (from 22.66 ± 5.32 to 25.63 ± 4.75 mmHg and from 0.14 ± 0.03 to 0.17 ± 0.03, respectively, mean ± SEM). The CD34(+) cell counts in bone marrow concentrate (BMC) decreased (correlation, p = 0.024) with age, even though there was no correlation between age and healing. An unexpected finding was made of relative, bone marrow lymphopenia in the initial bone marrow concentrates in patients who failed ABMSC therapy (21% of MLA). This difference was statistically significant (p < 0.040). We conclude ABMSC therapy results in 79% limb salvage in patients suffering from CLI and FU. In the remaining 21% lymphopenia and thrombocytopenia were identified as potential causative factors, suggesting that at least a partial correction with platelet supplementation may be beneficial.


Assuntos
Transplante de Medula Óssea , Extremidades/irrigação sanguínea , Úlcera do Pé/terapia , Isquemia/terapia , Idoso , Amputação Cirúrgica , Índice Tornozelo-Braço , Antígenos CD34/metabolismo , Doença Crônica , Feminino , Humanos , Salvamento de Membro , Linfopenia/etiologia , Masculino , Pessoa de Meia-Idade , Transplante Autólogo
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