1.
Bioorg Med Chem Lett
; 13(18): 2961-6, 2003 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12941312
RESUMO
Through chemical modification and X-ray crystallography we identified the 2,4-bis anilino pyrimidines as potent inhibitors of CDK4. Herein, we describe the optimisation of this series.