1.
Spectrochim Acta A Mol Biomol Spectrosc
; 61(11-12): 2788-95, 2005 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16043079
RESUMO
A series of novel isoindolone derivatives (13-18) were prepared in goods yields by applying the TAWERS methodology. A general approach for formation of isoindolones from the aza-Wittig reaction of iminophosphoranes with dialdehydes under neutral and mild conditions was realized. Using 1D NMR a [1,3]-hydride migration was detected. The assignment of the structures and conformation behavior of the derivatives was achieved using 1D and 2D NMR (NOESY, DEPT, HMQC, and HMBC).