Hand-arm Vibration Syndrome in Farmers and its Correlation with Degenerative Triangular Fibrocartilage Complex Injury.

CONTEXT: Hand-arm vibration syndrome (HAVS) is an occupational disease that affects workers who are exposed to vibrations. Farmers are prone to various musculoskeletal and cumulative trauma disorders. These occur owing to overuse, degeneration, and excess physical efforts along with whole-body vibrations- owing to the use of farming equipment such as tractors and harvesters. AIMS: Aims of the study were to find out the prevalence of various symptoms of HAVS among farmers using tractors, harvesters, etc., and to find out the correlation of triangular fibrocartilage complex (TFCC) injury with HAVS. SUBJECTS AND METHODS: A prevalence study was conducted among farmers. Farmers were selected by random sampling method and were asked to fill-up a HAVS surveillance questionnaire. The handgrip strength was recorded with a hand dynamometer. Assessment of carpal tunnel syndrome was done, and correlation of HAVS with TFCC injury was assessed. RESULTS: Data from 100 farmers was obtained and analyzed. The musculoskeletal symptoms of HAVS, more specifically pain was prevalent (n = 65), followed by sensorineural symptoms (n = 70), and the vascular symptoms were less common (n = 43). HAVS accounts for a prevalence of 64% with 39% of farmers having TFCC injury along with HAVS (P value = <0.0001). CONCLUSIONS: These findings reported in the study provide a better understanding of the impact and extent of HAVS in farmers. There is a significant prevalence of HAVS with mild symptoms of vascular component, mild to moderate symptoms of sensorineural component, and significant involvement of the musculoskeletal component. In addition, TFCC injury is correlated with HAVS.

Prevalence of Upper Cross Syndrome in Laundry Workers.

CONTEXT: Upper crossed syndrome is caused by weakness in one group of muscles and tightness in other group of muscles. Deep-neck flexor weakness and tight pectorals and sternocleidomastoid contribute to this syndrome. This syndrome mainly arises as a result of muscular imbalance that usually develops between weak and tonic muscles. Laundry workers tend to develop this syndrome due to the nature of their work. AIMS: The aim of the study is to find the prevalence of upper crossed syndrome in laundry workers. SUBJECTS AND METHODS: A prevalence study was conducted among laundry workers. Laundry workers were selected by random sampling method. They were assessed by performing various special tests for tightness and weakness of the muscles. Oswestry neck disability index questionnaire was then filled up by the population included. RESULTS: Data from fifty laundry workers were obtained and analyzed. The symptoms of upper crossed syndrome were present (n = 14) in the population with mild neck disability (n = 4) and moderate neck disability (n = 11) and no disability (n = 35). CONCLUSIONS: These findings reported in the study provide a better understanding of impact and the extent of upper crossed syndrome. We found out that there is a significant prevalence of upper crossed syndrome in laundry workers. Neck pain presents as the main symptom, and these patients also present with forward head-and-neck posture.

Facile synthesis of α-alkoxymethyltriphenylphosphonium iodides: new application of PPh3/I2.

An efficient one pot method for the synthesis of α-alkoxymethylphosphonium iodides is developed by using PPh3/I2 combination at room temperature. Reaction conditions are found general to synthesize wide range of structurally variant alkoxymethylphosphonium iodides in high yield (70-91%). These new functionalized phosphonium salts are further used in stereoselective synthesis of vinyl ethers as well as in carbon homologation of aldehydes.

Nutritional assessment and antioxidant analysis of 22 date palm (Phoenix dactylifera) varieties growing in Sultanate of Oman

OBJECTIVE@#To assess the nutritional values and antioxidant analysis of 22 varieties of date palm (Phoenix dactylifera) fruit collected from various regions of the Sultanate of Oman.@*METHODS@#Nutritional parameters including moisture, fats, fiber, proteins, carbohydrates, and energy value were determined using standard methods of Association of Official Analytical Chemists. The antioxidant activity was screened for their free radical scavenging properties using ascorbic acid as a standard antioxidant. Free radical scavenging activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl free radical.@*RESULTS@#The results of the date fruits (dried/tamar stage) revealed significantly higher moisture (15%-21%), dry matter (78%-86%), ash content (1.0%-2.0%), fiber (1.0%-2.5%), fat (0.1%-0.7%), protein (1.8%-3.8%), nitrogen (0.25%-0.55%), carbohydrates (74.5%-82.4%), and energy values (307-345.5 kcal/100 g). The antioxidant activity ranged between 40% and 86% depending upon the type of date and location. Overall, Khalas, Fardh and Khasab have significantly higher nutritional attributes; however, other varieties such as Barshi, Qush LuLu, Handal, and Khunaizi also have comparable nutritional values. The cluster analysis further evidenced the correlation of proximate parameters in different locations. Moreover, the nutritional and antioxidant attributes of similar date varieties collected from different locations were slightly varied.@*CONCLUSIONS@#The present finding helps in understanding the nutritional significance of different date varieties in Oman while the lesser known varieties can be improved through sustainable horticultural practices as a valuable product. The study further reveals that the consumption of these dates' fruits would exert several beneficial effects by virtue of their antioxidant activity.

Analgesic effects of crude extracts and fractions of Omani frankincense obtained from traditional medicinal plant Boswellia sacra on animal models

OBJECTIVE@#To investigate the analgesic effect of Boswellia sacra (B. sacra), which could support the Omani traditional uses of frankincense for muscle, stomach, and arthritis pain.@*METHODS@#The crude extract, the essential oils and various sub-fractions of the crude methanol extract (each 300 mg/kg of the body weight of the animal) obtained from the resin of B. sacra were administered orally, and were evaluated for their analgesic activities by using two well known models of pain in mice, viz. acetic acid induced writhing test and formalin induced pain test in mice.@*RESULTS@#Of 13 samples, almost all of them were effective at an orally administered dose of 300 mg/kg of the body weight. The acetic acid induced writhes were inhibited in all the three phases with comparable values to the standard drug aspirin (300 mg/kg of body weight) with inhibition of 67.6% in phase I, 66.8% in phase II, and 37.9% in phase III. At the same time, all the tested samples were found effective in both the early and the late phases of formalin test. In formalin test, most of the tested samples showed more inhibitory effects as compared to the standard drug aspirin (300 mg/kg of body weight), which showed 36.2% and 29.6% inhibition in early and late phases respectively. Among the tested samples, the most significant inhibition was produced by Shabi frankincense oil (57.5% in early phase, and 55.6% in late phase). Interestingly, the extracts showed comparable percentage of inhibition to the oil and found in the following order: 60% chloroform/n-hexane sub-fraction (55.3% in early phase, and 66.7% in late phase), and 70% chloroform/n-hexane sub-fraction (59.6% in early phase, and 63.0% in late phase).@*CONCLUSIONS@#The present study provided the scientific justification about the analgesic properties of the essential oils, extract, and various sub-fractions obtained from the resin of B. sacra, thus validating its use in traditional folk medicines and other products; and hence supporting the development in the analgesic properties of bioactive natural substances.

Analgesic effects of crude extracts and fractions of Omani frankincense obtained from traditional medicinal plant Boswellia sacra on animal models

Objective: To investigate the analgesic effect of Boswellia sacra (B. sacra), which could support the Omani traditional uses of frankincense for muscle, stomach, and arthritis pain. Methods: The crude extract, the essential oils and various sub-fractions of the crude methanol extract (each 300 mg/kg of the body weight of the animal) obtained from the resin of B. sacra were administered orally, and were evaluated for their analgesic activities by using two well known models of pain in mice, viz. acetic acid induced writhing test and formalin induced pain test in mice. Results: Of 13 samples, almost all of them were effective at an orally administered dose of 300 mg/kg of the body weight. The acetic acid induced writhes were inhibited in all the three phases with comparable values to the standard drug aspirin (300 mg/kg of body weight) with inhibition of 67.6% in phase I, 66.8% in phase II, and 37.9% in phase III. At the same time, all the tested samples were found effective in both the early and the late phases of formalin test. In formalin test, most of the tested samples showed more inhibitory effects as compared to the standard drug aspirin (300 mg/kg of body weight), which showed 36.2% and 29.6% inhibition in early and late phases respectively. Among the tested samples, the most significant inhibition was produced by Shabi frankincense oil (57.5% in early phase, and 55.6% in late phase). Interestingly, the extracts showed comparable percentage of inhibition to the oil and found in the following order: 60% chloroform. /n-hexane sub-fraction (55.3% in early phase, and 66.7% in late phase), and 70% chloroform. /n-hexane sub-fraction (59.6% in early phase, and 63.0% in late phase). Conclusions: The present study provided the scientific justification about the analgesic properties of the essential oils, extract, and various sub-fractions obtained from the resin of B. sacra, thus validating its use in traditional folk medicines and other products; and hence supporting the development in the analgesic properties of bioactive natural substances.

Nutritional assessment and antioxidant analysis of 22 date palm (Phoenix dactylifera) varieties growing in Sultanate of Oman

Objective: To assess the nutritional values and antioxidant analysis of 22 varieties of date palm (Phoenix dactylifera) fruit collected from various regions of the Sultanate of Oman. Methods: Nutritional parameters including moisture, fats, fiber, proteins, carbohydrates, and energy value were determined using standard methods of Association of Official Analytical Chemists. The antioxidant activity was screened for their free radical scavenging properties using ascorbic acid as a standard antioxidant. Free radical scavenging activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl free radical. Results: The results of the date fruits (dried/tamar stage) revealed significantly higher moisture (15%-21%), dry matter (78%-86%), ash content (1.0%-2.0%), fiber (1.0%-2.5%), fat (0.1%-0.7%), protein (1.8%-3.8%), nitrogen (0.25%-0.55%), carbohydrates (74.5%-82.4%), and energy values (307-345.5 kcal/100 g). The antioxidant activity ranged between 40% and 86% depending upon the type of date and location. Overall, Khalas, Fardh and Khasab have significantly higher nutritional attributes; however, other varieties such as Barshi, Qush LuLu, Handal, and Khunaizi also have comparable nutritional values. The cluster analysis further evidenced the correlation of proximate parameters in different locations. Moreover, the nutritional and antioxidant attributes of similar date varieties collected from different locations were slightly varied. Conclusions: The present finding helps in understanding the nutritional significance of different date varieties in Oman while the lesser known varieties can be improved through sustainable horticultural practices as a valuable product. The study further reveals that the consumption of these dates' fruits would exert several beneficial effects by virtue of their antioxidant activity.

An improved method of synthesis of N-protected L-amino acids as their benzoxymethyl esters.

An improved method for the synthesis of L-amino acids as their benzoxymethyl esters has been reported. All the synthesized compounds were characterized by (1)H NMR, EI-MS and IR spectroscopic methods.