RESUMO
Prolonged wound discharge is a common postoperative complication of orthopaedic procedures and a risk factor for implant-related infection. Occlusive wound closure methods have previously been suggested to reduce or even prevent this complication. We performed a randomised controlled trial on 70 patients who underwent surgical treatment for metastatic bone disease involving the proximal femur at our centre between January 2017 and August 2018. At conclusion of the tumour resection and endoprosthetic reconstruction procedure, patients were randomised to either occlusive wound closure (n = 35), using the Dermabond Prineo-22 skin closure system, or routine wound closure with conventional skin staples (n = 35). Skin closure with occlusive wound closure resulted in a lesser degree (P < .0001) and shorter duration of postoperative wound discharge (HR 2.89 [95% CI 1.6-5.05], P < .0018). Compared with staples, surgical wounds were already dry after a mean of 3.5 days [95% CI 3.2-3.9] versus 6.1 days [95% CI 4.8-7.3] (P < .0001). Prolonged wound discharge for 7 days or more was observed in 23% of patients (n = 8) in the Staples-group but was entirely absent in the occlusive wound closure group (P < .003). This study provides strong evidence that occlusive wound closure reduces frequency, degree, and duration of wound discharge in a patient population at particularly high risk for this complication.
Assuntos
Doenças Ósseas , Neoplasias , Humanos , Técnicas de Sutura/efeitos adversos , Técnicas de Fechamento de Ferimentos , Complicações Pós-Operatórias/prevenção & controle , Complicações Pós-Operatórias/etiologia , Suturas , Fêmur/cirurgia , Doenças Ósseas/etiologia , Infecção da Ferida Cirúrgica/etiologiaRESUMO
Glomus tumours are rare dermal tumours, which very seldom can be seen viscerally. The majority is benign small tumours of the skin. Malignancy has been reported in very few cases worldwide. The diagnosis is made clinically supported by MRI-scans and biopsy of the lesion. We present a case story of a 14-year-old boy, who had an infiltrative glomus tumour of the foot. The tumour met the criteria for malignancy and was operated radically by amputation of the forefoot. The post-operative period was uncomplicated and no metastases were observed neither clinically nor by PET-CT scans.
Assuntos
Tumor Glômico/cirurgia , Articulação Metatarsofalângica/cirurgia , Metatarso/cirurgia , Adolescente , Amputação Cirúrgica , Tumor Glômico/patologia , Humanos , Masculino , Articulação Metatarsofalângica/patologia , Metatarso/patologiaRESUMO
BACKGROUND: Regenerex is a novel porous titanium construct with a three-dimensional porous structure and biomechanical characteristics close to that of normal trabecular bone. The aim of this study was to compare this novel construct to a well-proven porous plasma sprayed tibial (PPS) implant after total knee arthroplasty. METHODS: Sixty-one patients scheduled for an uncemented TKA were randomized to receive either a novel highly porous titanium construct Regenerex or the PPS tibial component. Radiostereometric analysis of the tibial components was performed postoperatively and at three, six, 12, and 24months with measurements of migration (segment motion and maximum total point motion (MTPM)). RESULTS: Knee and function scores improved significantly from preoperatively to two-year follow-up. For both the Regenerex and the PPS the majority of migration appeared during the first three months and then stabilized. No statistically significant differences in MTPM were found in any follow-up between three and 24months. The Regenerex group had a lower migration rate between 12 and 24months compared with the PPS implants (p=0.03) but the PPS group had an initial significantly lower subsidence (p=0.04). CONCLUSION: In conclusion the Regenerex implant could prove an effective scaffold material for coating of uncemented implants but did no better than the PPS component at 24months of follow-up. ClinicalTrials.gov identifier: NCT01936415.
Assuntos
Artroplastia do Joelho , Prótese do Joelho , Osteoartrite do Joelho/cirurgia , Desenho de Prótese , Titânio , Idoso , Cimentação , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Osteoartrite do Joelho/diagnóstico por imagem , Osteoartrite do Joelho/fisiopatologia , Porosidade , Estudos Prospectivos , Falha de Prótese , Análise Radioestereométrica , Amplitude de Movimento Articular , TíbiaRESUMO
BACKGROUND: The relative effectiveness of different methods for reconstructing large bone loss at the proximal tibia in revision total knee arthroplasty (rTKA) has not been established. The aim of this study was to evaluate the clinical and radiological outcome after the use of trabecular metal technology (TMT) cones for the reconstruction of tibial bone loss at the time of rTKA. METHODS: Thirty-six patients had rTKA with the use of a TMT Cone. Bone loss was classified according to the AORI classification and 25% of the patients suffered from T3 AORI defects and 75% of the patients from T2 AORI defects. Implants used were from the NexGen series. At follow-up, radiographs were evaluated according to the Knee Society Roentgenographic Scoring System. Knee and function score was calculated using the Knee Society Clinical Rating System. Average follow-up time was 47 months (range 3-84 months). RESULTS: Clinical and radiological follow-up data were available in 30 patients and missing in six patients: two died and four patients had re-revision (reinfection (n=2), aseptic loosening (n=1), and knee hyperextension (n=1)). Knee- and function scores (follow-up 43 months (range 12-84 months)) improved from 42 to 77 points (p<0.0005) and 19 to 63 points (p<0.0005) respectively. Twenty-seven patients (follow-up 44 months (range 12-72 months)) showed no signs of radiological loosening of rTKA components. CONCLUSION: Based on our study, it was concluded that the use of TMT Cones provided an effective treatment in terms of surgical efficacy, clinical results and radiological results and was evidently at least as effective as the other options reviewed in the literature. LEVEL OF EVIDENCE: IV.
Assuntos
Artroplastia do Joelho/métodos , Reabsorção Óssea/cirurgia , Articulação do Joelho/cirurgia , Prótese do Joelho , Tantálio/uso terapêutico , Tíbia/cirurgia , Idoso , Idoso de 80 Anos ou mais , Bioprótese , Reabsorção Óssea/diagnóstico por imagem , Reabsorção Óssea/fisiopatologia , Substitutos Ósseos , Feminino , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/fisiopatologia , Masculino , Pessoa de Meia-Idade , Radiografia , ReoperaçãoRESUMO
"Trabecular Metal Cone" (TM Cone) (Zimmer, Inc, Warsaw, Ind) for reconstruction of bone loss in the proximal tibia during revision total knee arthroplasty is now optional. Forty patients were randomized to receive revision total knee arthroplasty with or without TM Cone (No TM Cone). The Anderson Orthopaedic Research Institute bone loss classification and NexGen revision system were used. Radiostereometric analysis was performed with 24 months of follow-up. Maximum total point motion: stable migration was seen in the TM Cone group. No statistically significant difference was found. Segment motion analysis at 24 months showed the same net direction of rotation for the groups around the y-, z-axis and around the x-, y-axis for translation. Tibial revision implants with TM Cone result in an early stable situation with less irregular migration pattern than revision without TM Cone.
Assuntos
Artroplastia do Joelho/instrumentação , Idoso , Feminino , Seguimentos , Humanos , Masculino , Metais , Pessoa de Meia-Idade , Próteses e Implantes , Análise Radioestereométrica , Reoperação , Rotação , TíbiaRESUMO
PURPOSE: Forty patients were enrolled in a prospective randomised study using conventional method or "Trabecular Metal Cone" (TM Cone) (Zimmer inc., Warsaw, USA) for reconstruction of bone loss of the proximal tibia during revision total knee arthroplasty (rTKA). The aim was to evaluate changes in bone mineral density (BMD) at the proximal tibia. MATERIAL AND METHODS: Thirty-six patients [median 67 years (range: 40-85 years)] received rTKA with NexGen® (Zimmer Warsaw, USA) revision system. Knee Society´s Knee Scoring System and the Anderson Orthopaedic Research Institute (AORI) bone classification was used. Changes in BMD were measured by dual energy X-ray absorptiometry (DEXA). RESULTS: Knee and function score improved in both groups. No significant changes between the groups were found. Changes in BMD within the two groups were quite similar. Overall decreases in BMD of 0.1 - 5.4 % were found in both groups (ROI 1-6) postoperative to 12 months of follow-up, except that ROI 7 showed an increase in BMD (0.8 - 1.3 %). After 24 months of follow-up, an increase in BMD was found along the stem (ROI 2-5) of 1.9 - 6.3 % , with significant changes in the TM Cone Group (ROI 3, 4, 5) . No significant changes in BMD between the groups were found. CONCLUSIONS: The bone remodelling pattern was almost the same in the two groups after two years.
Assuntos
Artroplastia do Joelho , Densidade Óssea , Reabsorção Óssea/diagnóstico , Prótese do Joelho , Tantálio , Tíbia/metabolismo , Absorciometria de Fóton , Adulto , Idoso , Idoso de 80 Anos ou mais , Artroplastia do Joelho/efeitos adversos , Remodelação Óssea/fisiologia , Reabsorção Óssea/etiologia , Reabsorção Óssea/cirurgia , Substitutos Ósseos , Feminino , Humanos , Articulação do Joelho/fisiopatologia , Articulação do Joelho/cirurgia , Masculino , Pessoa de Meia-Idade , Osseointegração , Complicações Pós-Operatórias/etiologia , Estudos Prospectivos , Desenho de Prótese , Recuperação de Função Fisiológica , Reoperação , Tíbia/diagnóstico por imagem , Resultado do TratamentoRESUMO
BACKGROUND: The effect of postoperative adaptive bone remodeling following a stemmed femoral implant in revision total knee arthroplasty (rTKA) is unknown. The aim of this study was to evaluate bone mineral density (BMD) changes of the distal femur following cemented rTKA with a 100-mm press-fit stem. MATERIALS AND METHODS: Sixteen consecutive patients were included in the study (age range 40-85 years; mean 63.5 years). NexGen(®) (Zimmer, Warsaw, IN, USA) cemented revision implants were used. All implants had the same press-fit femoral stem length of 100 mm. Clinical examinations with evaluation of the knee function using the Knee Society's Knee Scoring System were used. Measurements of BMD (g/cm(2)) were performed by dual-energy X-ray absorptiometry (DEXA) using a Norland XR-46 (Norland Corp. Fort Atkinson, WI, USA) bone densitometer. RESULTS: Knee and function scores improved significantly (P = 0.005) from the preoperative values to 1 year of follow-up. In regions of interest (ROI) 1-4, a significant increase in BMD (3.5-6.0%) after 6 months was seen. This increase only remained significant in ROI 4 (4.0%, P = 0.01) at 1 year of follow-up. CONCLUSIONS: The increase in BMD is probably the result of increased mobility and load on the extremity after implantation of a well-functioning rTKA.
Assuntos
Artroplastia do Joelho/métodos , Densidade Óssea/fisiologia , Remodelação Óssea/fisiologia , Fêmur/fisiologia , Prótese do Joelho , Absorciometria de Fóton , Adulto , Idoso , Idoso de 80 Anos ou mais , Cimentos Ósseos , Intervalos de Confiança , Feminino , Fêmur/diagnóstico por imagem , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Desenho de Prótese , Estudos de Amostragem , Fatores de TempoRESUMO
BACKGROUND: The outcome of performing isolated tibial polyethylene insert exchange (ITPIE) after total knee arthroplasty (TKA) is under debate. We evaluated the survival probability of ITPE after uncemented TKA. METHOD: 27 patients (27 knees) with an ITPIE performed mean 9 (0.9-17) years after the initial TKA were included in the study (22 patients also had the patellar component replaced simultaneously). All patients had their exchange performed at our department between 1997 and 2001 and had their latest follow-up examination mean 40 (8-71) months after the exchange. RESULTS: During the follow-up, 2 patients had total knee revision because of aseptic loosening and 2 patients had isolated patella component exchange (in 1 of the patients, combined with a new ITPIE). Kaplan-Meier survival analysis gave a survival probability of 80% at 34 months of follow-up. INTERPRETATION: The short-term survival after an ITPIE was similar to that of a total knee revision with exchange of all components. Since the ITPIE is a much smaller operation with fast rehabilitation, we recommend it in elderly patients with a well-fixed and wellaligned prosthesis without surface damage of the components.