Review of Active Constituents and Pharmacological Activities of Schisandrae Chinensis Fructus / 中国实验方剂学杂志

Schisandrae Chinensis Fructus is dry,mature fruits of magnolia plant Schisandra chinensis. In recent years,domestic and foreign scholars have made a lot of studies on active constituents of S. chinensis and pharmacological activities. This article systematically organizes the active constituents and pharmacological activities of S. chinensis. It was found that fruit,seeds,roots,stems and leaves of S. chinensis and other medicinal parts mainly contained lignans,volatile oils,triterpenoids,polysaccharides and flavonoids. And lignans were the main characteristic active ingredients of S. chinensis,triterpenoids,polysaccharides and volatile oils were the secondary active ingredients,and the activity of flavonoids had rarely been reported. According to the pharmacological study of S. chinensis,S. chinensis lignans had certain effects on the central nervous system,cardiovascular system,liver,kidney and reproductive system,with anti-oxidation,anti-tumor,anti-bacterial and anti-HIV effects. Other chemical components also had good pharmacological activities,but were less studied than lignans. With dual functions in medicine and food, it was widely used as a health product and medicine. This article systematically summarized the active constituents and pharmacological activities of S. chinensis,and provided an important reference and basis for the further development of the health product and medicine of S. chinensis in the future.

Chemical constituents from Hydrangea macrophylla / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate chemical constituents from Chinese herbal medicine Hydrangea macrophylla.</p><p><b>METHOD</b>The compounds were separated and purified by column chromatography over silica gel, ODS, and preparative HPLC. Their structures were identified by spectral methods including 1H, 13C-NMR and MS.</p><p><b>RESULT</b>Eleven compounds were isolated and identified as zeorin, hopane-6, 22-diol (1), botulin (2), betulinic acid (3), 2-ethyl-3-methyl-maleimide-N-beta-D-glucopyranoside (4), uridine (5), thymidine (6), adenosine (7), nicotinamide (8), methyl pyroglutamate (9), hydrangenol (10) and hydrangenol-4'-O-beta-D-glucopyranoside (11), respectively.</p><p><b>CONCLUSION</b>Compounds 14 and 7-9 were obtained from the genus Hydrangea for the first time.</p>