RESUMO
Objective To investigate the clinical effect of hyper-fractionated three-dimensional conformal radiotherapy (3DCRT) combined with transcatheter arterial chemeembolization (TACE) for heating patients with inoperable primary liver cancer.Methods One hundred and two patients with inoperable advanced primary liver cancer were divided by random digits table method into control group with 49 cases treated with TACE and observation group with 53 cases treated with hyper-fractionated 3DCRT combined with TACE.The short-term efficacy,adverse reaction and survival rate of the 1st,2nd and 3rd year and serum alpha-fetoprotein (AFP) expression after treatment in two groups were observed.Results The complete remission rate,progress rate and total efficiency were 17.0％ (9/53),11.3％ (6/53),73.6％ ( 39/53 ) in observation group,2.0％( 1/49 ),28.6％ (14/49),51.0％(25/49 ) in control group.There were significant differences between two groups (P ＜ 0.05).There was no statistical significance in adverse reactions between two groups ( P ＞ 0.05 ).The survival rates of the 1 st,2nd and 3rd year in control group were 51.0％ ( 25/49 ),28.6％(14/49),14.3％(7/49),the median survival time was 15 months;while those in observation groupwere 71.7％(38/53),52.8％(28/53),39.6％(21/53) and 20 months.The survival rates of the 2nd and 3rd year in observation group were significantly higher than those in control group respectively (P ＜0.05 or ＜0.01 ).The rate of patients with no obvious serum AFP protein change between observation group [ 9.8％(4/41) ] and control group [ 31.6％(12/38) ] had statistical significance (P ＜ 0.05).Conclusion Hyper-fractionated 3DCRT combined with TACE for treating patients with inoperable primary liver cancer has good clinical efficacy,it is worthy of clinical practice.
RESUMO
Objective To study the application value of cytological examination and biopsy for the transbronchial needle aspiration (TBNA) in the diagnosis of cancer. Methods 101 patients with lung disease by CT that need TBNA examination to make final diagnosis were selected. They were executed with routine ex-amination of TBNA. And then pathologic biopsy and cytological examination were applied on the collection sam-pies. Results 86 patients among the 96 subjects were finally diagnosed by TBNA. So the ratio of final diagno-sis was 94. 5%. And the positive ratios about transbronchial needle aspiration and ring clamp biopsy, also brush biopsy, were 71.4% 、75.8%、 61.5%. Only 5 patients were histodiagnosed by just transbrenchial needle aspiration. Conclusion TBNA plays an important role on the diagnosis of lung tumor with different types. And the combination of three methods can improve the diagnosis pro-gressively.
