Substance Use-Related Alterations of Social Decision Making in a Longitudinal Cohort of Young Adults.

BACKGROUND: Substance use disorders are associated with severe negative social and health-related outcomes. Evidence has accumulated that long-term substance use is associated with alterations in social interaction behavior, which likely contributes to the vicious cycle of substance use disorder. However, little is known about whether these social problems originate from contextual factors only or also from the substance use itself-in other words, if they are predisposed or substance induced. METHODS: We studied the causation behind behavioral alterations of substance users over a 9-year period (ages 11-20 years) in an urban age cohort (N = 1002) with a high prevalence of substance use at age 20. We identified common substance use patterns using toxicological hair analysis, examined behavioral alterations with incentivized games, and used teacher assessments across different ages to determine the causes and effects that underlie substance use-related impairments in social interaction. RESULTS: We found that opioid and stimulant users showed reduced prosocial behavior compared with nonusers, particularly in interpersonal trust and perspective taking (e.g., they were approximately 50% less likely to trust others). Our longitudinal analyses suggest a causal relationship between the nonmedical use of prescription opioids and impaired social behavior, whereas impairments among stimulant users seem to be partially predisposed. Moreover, women tended to be more severely affected by opioid use than men. However, no behavioral alterations were found among young adult cannabis or ecstasy users. CONCLUSIONS: Highly addictive substances such as opioids can impair users' social behavior by undermining fundamental human interaction, thereby fueling a vicious cycle of substance use and social isolation.

Lumbosacral Traumatic Spondylolisthesis L5 to S1-Classification and Surgical Management of a Difficult Presentation.

INTRODUCTION: Lumbosacral traumatic spondylolisthesis L5-S1 is a rare clinical entity that compromises the stability of the L5 vertebra by displacing it anteriorly, laterally, or posteriorly on the S1 vertebral body secondary to osteotendinous and/or articular compromise of this segment due to trauma. This pathology is difficult to classify and manage; although surgical management remains the gold standard, short- and long-term results in the literature are scarce and highly variable. PATIENT PRESENTATION: We present the case of a 53-year-old patient with lumbar trauma due to a free fall from a height of 6 meters. The fall resulted in cauda equina syndrome secondary to lumbosacral traumatic spondylolisthesis L5-S1, which required immediate surgical management. INTERVENTION AND OUTCOME: For surgical management, we used a posterior approach for L5-S1 transpedicular screw fixation, spinal decompression, bilateral root foraminotomy of L5, and L5-S1 open transforaminal lumbar interbody fusion with open reduction. After the operation, the patient reported immediate improvement of postoperative lower extremities pain and was discharged on the third postoperative day after achieving clinical improvement with physical therapy and bladder rehabilitation exercises. CONCLUSION: Lumbosacral traumatic spondylolisthesis L5-S1 is an unusual pathology that requires further study as there is currently no standardized classification. Surgical management is the gold standard and includes open reduction with short transpedicular screw fixation in segment L5-S1 and other surgical interventions such as extension to the pelvis with iliac screws, screws to the L4 vertebral body, and use of lumbar interbody fusion cages.

Perceptions of Scientific Authorship Revisited: Country Differences and the Impact of Perceived Publication Pressure.

Relying on data collected by the Zurich Survey of Academics (ZSoA), a unique representative online survey among academics in Germany, Austria, and Switzerland (DACH region), this paper replicates Johann and Mayer's (Minerva 57(2):175-196, 2019) analysis of researchers' perceptions of scientific authorship and expands their scope. The primary goals of the study at hand are to learn more about (a) country differences in perceptions of scientific authorship, as well as (b) the influence of perceived publication pressure on authorship perceptions. The results indicate that academics in Switzerland interpret scientific authorship more leniently than their colleagues in Germany and Austria. The findings further indicate that, as perceived pressure to publish increases, researchers are more likely to belong to a group of academics who hold the view that any type of contribution/task justifies co-authorship, including even those contributions/tasks that do not justify co-authorship according to most authorship guidelines. In summary, the present study suggests that action is required to harmonize regulations for scientific authorship and to improve the research culture.

Mapping mental models of science communication: How academics in Germany, Austria and Switzerland understand and practice science communication.

The mental models that individual scholars have of science communication - how it works, what it is supposed to achieve and so on - shape the way these academics actually communicate to the public. But these mental models, and their prevalence among scholars, have rarely been analysed. Drawing on a large-scale, representative web survey of academics at universities in Germany, Austria and Switzerland (n = 15,778) from 2020, we identify three mental models that are prevalent among scholars, and that correspond to conceptual models found in science communication theory: 'Public Understanding of Science', 'Public Engagement with Science' and 'Strategic Science Communication'. The results suggest that the 'Strategic Science Communication' model is particularly prevalent among academics in precarious employment and female scholars. Extrinsically motivated academics, that is, those under pressure to win grants, also seem to use science communication more strategically. The 'Public Engagement' model is prevalent among older and female scholars, while 'Public Understanding' is particularly prevalent among scholars who find their work especially meaningful. Findings also reveal that academics' mental models largely align with the way they practice science communication.

[Parenchymal lung changes on CT in patients with coronavirus disease 2019 (COVID-19)].

Introduction Infections due to COVID-19 can lead to life threatening pneumonia. Accompanying severe disease are more prominent pulmonary changes on Computed Tomography (CT) scan of the chest. The goal of this study was to describe pulmonary CT changes during acute COVID-19 and at follow up and whether the extent of changes correlate with severity of illness, demographics or other risk factors. Materials and methods Included in this study are all individuals that had confirmed COVID-19 and came for a follow up CT of the chest at Landspitali from May to September 2020. Information regarding medical history was obtained retrospectively from medical charts. All CT scans were reviewed using an international staging system to evaluate the extent of lung changes. Results Eighty-five patients with a mean age of 59 years were included in the study. Sixty patients (71%) were hospitalized during the acute phase and 18 (21%) were admitted to the ICU. During the acute phase more pronounced lung involvement was seen in males and patients admitted to the ICU. At follow-up females had less lung involvement but there was a significant relationship between a higher CT score and age, ICU admissions and days in the ICU. Full recovery was seen at follow-up CT in 31% of patients (median 68,5 days between acute and follow-up imaging). Conclusion Patients with severe COVID-19 have more pronounced lung involvement on CT than patients with milder disease during the acute phase and follow-up. Older patients and males are at greater risk of acute and persistent COVID-19 related lung changes.

Correction: Satisfaction of scientists during the COVID-19 pandemic lockdown.

[This corrects the article DOI: 10.1057/s41599-020-00618-4.].

Channels of participation: Political participant types and personality.

This article employs a person-centred approach to test the relationship between personality traits and empirically defined political participant types. We argue that it is more appropriate to focus on types of participants to test the relationship between personality and political participation than on individual modes or latent dimensions of political participation. Our reasoning is that the person-centred approach allows us to learn more about how and why citizens combine different modes of participation from a tool kit of available political activities to achieve a goal as a function of their personality. We rely on data collected by the German Longitudinal Election Study 2017 (GLES, ZA6801). On the basis of a set of survey questions enquiring on political activities that people take part in, Latent Class Analysis allows us to identify three political participant types (inactives, voting specialists, and complete activists). The 10-item Big Five Inventory (BFI-10) measures respondents' personality traits. Our findings suggest that conscientious people are more likely to affiliate with the voting specialists and extroverts with the more active participant types in Germany.

Intra-Campaign Changes in Voting Preferences: The Impact of Media and Party Communication.

An increasing number of citizens change and adapt their party preferences during the electoral campaign. We analyze which short-term factors explain intra-campaign changes in voting preferences, focusing on the visibility and tone of news media reporting and party canvassing. Our analyses rely on an integrative data approach, linking data from media content analysis to public opinion data. This enables us to investigate the relative impact of news media reporting as well as party communication. Inherently, we overcome previously identified methodological problems in the study of communication effects on voting behavior. Our findings reveal that campaigns matter: Especially interpersonal party canvassing increases voters' likelihood to change their voting preferences in favor of the respective party, whereas media effects are limited to quality news outlets and depend on individual voters' party ambivalence.

Voting at 16: Turnout and the quality of vote choice.

Critics of giving citizens under 18 the right to vote argue that such teenagers lack the ability and motivation to participate effectively in elections. If this argument is true, lowering the voting age would have negative consequences for the quality of democracy. We test the argument using survey data from Austria, the only European country with a voting age of 16 in nation-wide elections. While the turnout levels of young people under 18 are relatively low, their failure to vote cannot be explained by a lower ability or motivation to participate. In addition, the quality of these citizens' choices is similar to that of older voters, so they do cast votes in ways that enable their interests to be represented equally well. These results are encouraging for supporters of a lower voting age.