Learning needs and perceived barriers and facilitators to end-of-life care: a survey of front-line nurses on acute medical wards.

OBJECTIVES: Caring for dying hospitalised patients is a healthcare priority. Our objective was to understand the learning needs of front-line nurses on the general internal medicine (GIM) hospital wards, and perceived barriers to, and facilitators of, optimal end-of-life care. METHODS: We developed an 85-item survey informed by the Theoretical Domains Framework and Capability-Opportunity-Motivation-Behaviour system. We included demographics and two main domains (knowledge and practice; delivering end-of-life care) with seven subsections. Nurses from four GIM wards and the nursing resource team completed this survey. We analysed and compared results overall, by Capability, Opportunity, and Motivation, and by survey domain. We considered items with median scores <4/7 barriers. We conducted an a priori subgroup analysis based on duration of practice (≤5 and >5 years). RESULTS: Our response rate was 60.5% (144/238). 51% had been practising for >5 years; most respondents were female (93.1%). Nurses had similar scores on the knowledge (mean 76.0%; SD 11.6%) and delivering care (mean 74.5% (8.6%)) domains. Scores for items associated with Capability were higher than those associated with Opportunity (median (first, third quartiles) 78.6% (67.9%, 87.5%) vs 73.9% (66.0%, 81.8%); p=0.04). Nurses practising >5 years had significantly higher scores on all analyses. Barriers included engaging with families having strong emotional reactions, managing goals of care conflicts between patients and families, and staffing challenges on the ward. Additional requested resources included formal training, information binders and more staff. Opportunities for consideration include formalised on-the-job training, access to comprehensive information, including symptom management at the end of life, and debriefing sessions. CONCLUSIONS: Front-line nurses reported an interest in learning more about end-of-life care and identified important barriers that are feasible to address. These results will inform specific knowledge translation strategies to build capacity among bedside nurses to enhance end-of-life care practices for dying patients on GIM wards.

Mapping sign-tracking and goal-tracking onto human behaviors.

As evidenced through classic Pavlovian learning mechanisms, environmental cues can become incentivized and influence behavior. These stimulus-outcome associations are relevant in everyday life but may be particularly important for the development of impulse control disorders including addiction. Rodent studies have elucidated specific learning profiles termed 'sign-tracking' and 'goal-tracking' which map onto individual differences in impulsivity and other behaviors associated with impulse control disorders' etiology, course, and relapse. Whereas goal-trackers are biased toward the outcome, sign-trackers fixate on features that are associated with but not necessary for achieving an outcome; a pattern of behavior that often leads to escalation of reward-seeking that can be maladaptive. The vast majority of the sign- and goal-tracking research has been conducted using rodent models and very few have bridged this concept into the domain of human behavior. In this review, we discuss the attributes of sign- and goal-tracking profiles, how these are manifested neurobiologically, and how these distinct learning styles could be an important tool for clinical interventions in human addiction.

Development and preliminary validation of the Anticipated Effects of Food Scale.

Expectancy theory has been widely applied in substance use research but has received less attention in eating behavior research. Measuring food expectancies, or the anticipated outcomes of eating specific foods, holds theoretical and practical promise for investigations into nonhomeostatic eating behavior. The current study developed and assessed the psychometric properties of a novel measure of positively and negatively valenced highly (e.g., sweets, salty snacks, fast foods, sugary drinks) and minimally (e.g., fruits, vegetables) processed food expectancies. The Anticipated Effects of Food Scale (AEFS) was adapted from a self-report of alcohol expectancies, piloted for item generation/retention and readability, and preliminarily validated in an adult sample (N = 247; Mage = 36.84; 53.3% male; 74.5% White). Consistent with the substance expectancies literature, AEFS positive highly processed food expectancies were associated with greater added sugars intake, r = .17, p = .009, and food addiction symptoms, r = .56, p < .001. Of note, AEFS negative minimally processed food expectancies were robustly associated with food addiction symptoms, r = .81, p < .001, and, together with AEFS positive highly processed food expectancies, explained 67% of the variance in food addiction symptoms. Furthermore, AEFS food expectancies demonstrated incremental validity with food addiction symptoms above and beyond general eating expectancies. The AEFS seems to be a psychometrically sound measure and can be used to investigate cognitive-affective mechanisms implicated in highly processed food intake and food addiction. Moreover, the present results provide new insight into potential food expectancy challenge intervention approaches for preventing nonhomeostatic eating behavior. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

Structured Documentation of Home Ventilator Settings in Children: A Quality Improvement Project.

INTRODUCTION: In children requiring long-term mechanical ventilation (LTMV), insufficient admission charting can lead to adverse events. Our purpose in this study was to create and evaluate a structured documentation tool of home LTMV settings to improve communication, documentation, and patient safety. METHOD: This study used a pretest-posttest survey of pulmonary unit nurses' satisfaction with the tool and perceptions of patient safety, chart reviews of documentation compliance, and reports of education session attendance. Mann-Whitney U and Fisher exact tests, category analyses, and descriptive statistics were applied. RESULTS: Nurses' reports of positive communication of LTMV settings increased from 54.5% to 100% (p = .002), overall satisfaction with associated documentation increased (p < .001), and witnessed related adverse events decreased from 50% to 18.75%. Nurse compliance for education attendance and documentation was 97.4% and 97.3%, respectively. DISCUSSION: Structured admission charting of LTMV settings should be continued and yielded improvements in pulmonary unit nurses' perceptions of communication, patient safety, and documentation compliance.

Food craving as a mediator between addictive-like eating and problematic eating outcomes.

BACKGROUND: There is growing interest and debate about whether an addictive process contributes to problematic eating outcomes, such as obesity. Craving is a core component of addiction, but there has been little research on the relationship between addictive-like eating, craving, and eating-related concerns. In the current study, we examine the effect of both overall food craving and craving for different types of food on the relationship between addictive-like eating symptoms and elevated body mass index (BMI) and binge eating episodes. METHODS: In a community sample (n=283), we conducted analyses to examine whether overall craving mediated the association between addictive-like eating and elevated BMI, as well as binge eating frequency. We also ran separate mediational models examining the indirect effect of cravings for sweets, fats, carbohydrates, and fast food fats on these same associations. RESULTS: Overall food craving was a significant partial mediator in the relationships between addictive-like eating and both elevated BMI and binge eating episodes. Cravings for sweets and other carbohydrates significantly mediated the relationship between addictive-like eating and binge eating episodes, while cravings for fats significantly mediated the relationship between addictive-like eating and elevated BMI. CONCLUSIONS: Craving appears to be an important component in the pathway between addictive-like eating and problematic eating outcomes. The current results highlight the importance of further evaluating the role of an addictive process in problematic eating behaviors and potentially targeting food cravings in intervention approaches.

Current considerations regarding food addiction.

"Food addiction" is an emerging area, and behavioral and biological overlaps have been observed between eating and addictive disorders. Potential misconceptions about applying an addiction framework to problematic eating behavior may inhibit scientific progress. Critiques of "food addiction" that focus on descriptive differences between overeating and illicit drugs are similar to early criticisms of the addictiveness of tobacco. Although food is necessary for survival, the highly processed foods associated with addictive-like eating may provide little health benefit. Individual differences are important in determining who develops an addiction. If certain foods are addictive, the identification of possible risk factors for "food addiction" is an important next step. Not all treatments for addiction require abstinence. Addiction interventions that focus on moderation or controlled use may lead to novel approaches to treating eating-related problems. Finally, addiction-related policies that focus on environmental (instead of educational) targets may have a larger public health impact in reducing overeating.

Nicotinic acetylcholine receptors: a comparison of the nAChRs of Caenorhabditis elegans and parasitic nematodes.

Nicotinic acetylcholine receptors (nAChRs) play a key role in the normal physiology of nematodes and provide an established target site for anthelmintics. The free-living nematode, Caenorhabditis elegans, has a large number of nAChR subunit genes in its genome and so provides an experimental model for testing novel anthelmintics which act at these sites. However, many parasitic nematodes lack specific genes present in C. elegans, and so care is required in extrapolating from studies using C. elegans to the situation in other nematodes. In this review the properties of C. elegans nAChRs are reviewed and compared to those of parasitic nematodes. This forms the basis for a discussion of the possible subunit composition of nAChRs from different species of parasitic nematodes. Currently our knowledge on this is largely based on studies using heterologous expression and pharmacological analysis of receptor subunits in Xenopus laevis oocytes. It is concluded that more information is required regarding the subunit composition and pharmacology of endogenous nAChRs in parasitic nematodes.