RESUMO
Androgenetic alopecia, also known as male and female pattern hair loss, is a very prevalent condition; however, approved therapeutic options are limited. Fractionated laser has been proposed to assist in penetration of topical medications to the cutaneous tissue. We present four cases of androgenetic alopecia that underwent treatment with a non-ablative erbium glass fractional laser followed by the application of topical finasteride 0,05% and growth factors including basic fibroblast growth factor, insulin-like growth factor, vascular endothelial growth factor, and copper peptide 1%. During all laser treatment sessions, eight passes were performed, at 7 mJ, 3-9% of coverage and density of 120 mzt/cm2. A positive response was observed in all of the four patients. Photographs taken 2 weeks after the last session showed improvement in hair regrowth and density. No significant side effects were observed.
Assuntos
Inibidores de 5-alfa Redutase/administração & dosagem , Alopecia/terapia , Finasterida/administração & dosagem , Peptídeos e Proteínas de Sinalização Intercelular/administração & dosagem , Terapia com Luz de Baixa Intensidade/métodos , Inibidores de 5-alfa Redutase/uso terapêutico , Adulto , Idoso , Terapia Combinada , Feminino , Finasterida/uso terapêutico , Humanos , Peptídeos e Proteínas de Sinalização Intercelular/uso terapêutico , Lasers de Estado Sólido , Terapia com Luz de Baixa Intensidade/efeitos adversos , MasculinoRESUMO
Cutaneous metastasis is a rare manifestation of visceral malignancies that indicates primarily advanced disease. Due to its low incidence and similarity to other cutaneous lesions, it is not uncommon to have a delayed diagnosis and a shortened prognosis. We describe the case of a patient who presented with a cutaneous nodule in the sternal region as a first sign of malignancy.
Assuntos
Adenocarcinoma/secundário , Neoplasias Gastrointestinais , Neoplasias Primárias Desconhecidas/patologia , Neoplasias Cutâneas/secundário , Idoso de 80 Anos ou mais , Biópsia , Evolução Fatal , Feminino , HumanosRESUMO
AbstractCutaneous metastasis is a rare manifestation of visceral malignancies that indicates primarily advanced disease. Due to its low incidence and similarity to other cutaneous lesions, it is not uncommon to have a delayed diagnosis and a shortened prognosis. We describe the case of a patient who presented with a cutaneous nodule in the sternal region as a first sign of malignancy.