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INTRODUCTION AND IMPORTANCE: Primary hepatic neuroendocrine neoplasms(PHNEN) are among the rarest primitive neuroendocrine neoplasms. Main prognostic factor is histological. We report an unusual case of a PHNEN with 21 years of evolution in the setting of a primary sclerosing cholangitis(PSC). CASE PRESENTATION: A 40 year old man presented in 2001 with clinical signs of obstructive jaundice. CT-scan and MRI showed a 4 cm large hypervascular proximal hepatic mass evoking hepatocellular carcinoma(HCC) or cholangiocarcinoma. Exploratory laparotomy found an aspect of advanced chronic liver disease of the left lobe. Extemporaneous biopsy of a suspicious nodule showed signs of cholangitis. Left lobectomy was performed and postoperatively the patient received ursodeoxycholic-acid and biliary stenting. After 11 years of follow-up, jaundice reappeared with a stable hepatic lesion.A percutaneous liver biopsy was done. Pathology showed a G1 neuroendocrine tumor. Endoscopy, imagery and Octreoscan were normal, supporting the diagnosis of PHNEN. PSC was diagnosed on tumor-free parenchyma. The patient is on liver transplantation waiting list. CLINICAL DISCUSSION: PHNENs are exceptional. Pathology findings, endoscopy and imagery are necessary to rule out an extra hepatic NEN with liver metastasis. While G1 NEN are known for their slow evolution, this 21 year latency is extremely rare. The presence of PSC adds to the complexity of our case. Surgical resection is recommended when possible. CONCLUSION: This case showcases the extreme latency of some PHNEN as well as possible overlap with PSC. Surgery is the most recognized treatment. Liver transplantation seems to be necessary for us, as the rest of the liver shows signs of PSC.
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BACKGROUND: The use of mesh has become nowadays a standard for hernia repairs. It allows a tension-free hernioplasty and has shown that it is an effective way to prevent recurrences. But complications have been described. Intraperitoneal migration of mesh plug is an uncommon complication. CASE REPORT: In this paper we report a case of a 57 year old male who has been operated on 12 years ago, he had a mesh plug repair for a ventral incisional hernia. The mesh migrated into the abdominal cavity and it was wrongfully taken for a locally advanced right colon cancer. Colonoscopy was done and biopsies were taken, but the results were not conclusive. He was operated on. We found the mesh that had migrated and eroded the hepatic flexure. There was a granulation tissue that also included some of the small intestine. There was also an abscess in the abdominal wall. He had an en-bloc resection of a part of the abdominal wall, small intestine and right colon. CONCLUSION: Mesh hernioplasty is a frequent, simple and effective procedure with a low recurrence rate but it can be associated to serious complications such as mesh migration.
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Echinococcosis/hydatidosis caused by Echinococcus granulosus has a widespread distribution in the human population of Tunisia, particularly in the north-west and centre-west of the country. In a recent study, the morphological features, fertility and viability of hydatid cysts that had been excised from patients in Tunis were explored, and the E. granulosus strain or genotype involved in each case was identified from morphology of the protoscolex hooks and the results of molecular genotyping. The hepatic cysts investigated came from 41 patients [31 women and 10 men, with a mean (S.E.) age of 43.41 (14.25) years] who were treated for cystic echinococcosis, by surgery but rarely with chemotherapy, at the La Rabta Hospital in Tunis, in the 12 months ending in June 2008. Most (56%) of these patients originated from rural areas in endemic governorates. Of the 60 hepatic cysts that were studied, 38.3% were located in the right lobe of the liver and 35.0% each involved both hepatic lobes. Almost a third (31.7%) of the excised cysts were degenerating, with the rest considered viable and either multivesicular (38.3%) or univesicular (30.0%). Almost all (93.3%) of the cysts were categorized as fertile, with a mean protoscolex viability of 21.8%. Protoscolex viability was relatively high in the viable univesicular cysts with a visible cyst wall and in the multivesicular and multiseptate cysts with daughter cysts, and lowest in the cysts that appeared to be solid calcified masses. The observed variation in protoscolex viability with cyst type, in cysts excised from patients before any chemotherapy, supports the cyst classification recommended by the World Health Organization but could also be compatible with the imaging-based 'Gharbi' classification. The results of the molecular genotyping showed that all 23 cysts investigated (which came from 20 of the patients) were caused by E. granulosus of the G1 genotype (also known as the 'sheep' or 'sheep-dog' strain).
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Equinococose Hepática/parasitologia , Echinococcus granulosus , Adolescente , Adulto , Idoso , Animais , Doenças do Cão/parasitologia , Cães , Equinococose Hepática/cirurgia , Equinococose Hepática/veterinária , Echinococcus granulosus/anatomia & histologia , Echinococcus granulosus/genética , Echinococcus granulosus/fisiologia , Feminino , Fertilidade , Genótipo , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Ovinos , Doenças dos Ovinos/parasitologia , Tunísia , Adulto JovemRESUMO
The psoas muscle is an uncommon location for hydatid cyst accounting for only 1 to 3% of cases. The purpose of this report is to describe the epidemiologic, clinical, paraclinical, and therapeutic features of primary hydatid cyst of the psoas muscle. A retrospective study conducted in Surgery Department A at the Rabta Hospital in Tunisia compiled a total of 9 cases of primary hydatid cyst of the psoas muscle treated between 1980 and 2006. There were 6 men and 3 women with a mean age of 42.8 years. Symptomatology was nonspecific with pain in 6 cases. Discovery was coincidental in two cases. Clinical examination detected a mass in the presents of an abdominal mass in 7 cases. Radiologic findings (ultrasound and/or CT scan) confirmed diagnosis in 8 cases. In one case a mistaken diagnosis of psoas muscle abscess was made in a patient with an infected hydatid cyst. Serological tests were performed in 4 cases and were positive in 3. All patients underwent surgical treatment. The extraperitoneal approach (Leriche) was used in 7 cases and the transperitoneal approach via median laparotomy in 2. In all cases the surgical procedure consisted of partial cystectomy leaving a part of the pericystic against neurovascular structures. There was no operative mortality. The only postoperative complication was urinary infection in one patient. Mean follow-up was 2.5 years. One local recurrence was observed 4 years after surgical treatment and required reoperation.
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Equinococose/diagnóstico , Músculos Psoas/parasitologia , Adulto , Idoso , Diagnóstico por Imagem , Equinococose/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Músculos Psoas/cirurgia , TunísiaRESUMO
Enterosalpingeal fistula is a rare complication of Crohn's disease which is rarely diagnosed preoperatively. We describe a new case of this complication suspected by CT scan and confirmed by hysterosalpingogram and contrast from the ileum. This case is about a 50-year-old woman suffering from ileal Crohn's disease diagnosed two years previously and actually complicated by stenosis and entero-salpingeal fistula. The treatment consisted on resection of the ileocaecal region with salpingectomy. Postoperative course was uneventful.
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Doença de Crohn/complicações , Doenças das Tubas Uterinas/etiologia , Fístula/etiologia , Doenças do Íleo/etiologia , Fístula Intestinal/etiologia , Meios de Contraste , Doença de Crohn/cirurgia , Doenças das Tubas Uterinas/cirurgia , Feminino , Fístula/cirurgia , Humanos , Histerossalpingografia , Doenças do Íleo/cirurgia , Fístula Intestinal/cirurgia , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
Le muscle psoas est une localisation exceptionnelle du kyste hydatique ne representant que 1 a 3des cas. Le but de ce travail est d'etudier les caracteristiques epidemio- logiques; cliniques; paracliniques et therapeutiques de cette entite. Notre etude est retrospective consecutive portant sur 9 cas de kystes hydatiques primitifs du psoas colliges entre 1980 et 2006 dans le service de chirurgie A de l'Hopital La Rabta. Il s'agissait de 6 hommes et 3 femmes dont l'age moyen etait de 42;8 ans. La symptomatologie etait atypique dominee par les douleurs retrouvees dans 6 cas. La decouverte etait fortuite dans deux cas. L'examen physique retrouvait une masse du flanc dans 7 cas. Le diagnostic etait confirme par la radiologie (echographie et/ou tomodensitometrie) dans 8 cas. Dans 1 cas; le diagnostic d'abces du psoas etait pose a tort chez un patient porteur d'un kyste hydatique infecte. La serologie hydatique pratiquee dans 4 cas etait positive dans 3 cas. Tous les patients etaient operes. La voie d'abord etait extra peritoneale (Leriche) dans 7 cas et transperitoneale a travers une laparotomie mediane dans 2 cas. Le geste a consiste dans tous les cas en une kystectomie partielle laissant une calotte de perikyste contre les elements vasculo-nerveux. La mortalite etait nulle. Un seul patient s'est complique en postoperatoire d'une infection urinaire. Le suivi moyen etait de 2;5 ans. Au cours de la surveillance postoperatoire; une seule recidive locale etait diagnostiquee a 4 ans postoperatoire ayant necessite une nouvelle intervention
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Equinococose , Músculos PsoasRESUMO
INTRODUCTION: Anastomotic leak or disruption is a grave complication of colorectal surgery. Protection of an at-risk anastomosis by an upstream open diverting colostomy (OC) reduces this gravity. An unopened upstream loop colostomy is a surgical alternative which may diminish the unpleasant consequences of an open colostomy while maintaining the option of diversion in case of need. The aim of this study is to report the results of this approach and to define its indications. MATERIAL AND METHODS: [corrected] We report a retrospective series of 34 cases of unopened diverting loop colostomy to protect an at-risk colorectal anastomosis. Indications for this procedure were stool-laden bowel (59%), low serum albumin (11.5%), local inflammation (11.5%), and very low placed anastomosis (17.5%). RESULTS: The loop colostomy was eventually opened after surgery in six cases because of anastomotic leakage diagnosed clinically and/or detected by water soluble contrast opacification which was performed routinely on the sixth post-operative day. In all six cases, there was no need for an urgent surgical intervention. In 28 cases, the anastomosis healed without complication and the exteriorized loop was returned to the abdominal cavity seven days after the initial surgery. This was a short, simple procedure with an average operating time of ten minutes. Average hospital stay after returning the unopened colostomy to the abdomen was two days. CONCLUSION: Unopened loop colostomy offers the advantages of protection of a colorectal anastomosis without proper morbidity or mortality, shorter hospitalization, and improved psychological comfort for the patient. It's principal indication is to minimize the risks related to leakage from an at-risk colorectal anastomosis.
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Adenocarcinoma/cirurgia , Colo/cirurgia , Colostomia/métodos , Neoplasias Retais/cirurgia , Reto/cirurgia , Anastomose Cirúrgica/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/prevenção & controle , Estudos RetrospectivosRESUMO
Two new cases of Menetrier's disease with gastric adenocarcinoma in two men aged 62 and 81 years, respectively, are reported. In both cases, the diagnosis was established by histologic examination of the operative specimen. Emphasis is placed on diagnostic difficulties and on the risk of malignant transformation of Menetrier's disease, which should be viewed as a precancerous gastric lesion.
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Adenocarcinoma/complicações , Gastrite Hipertrófica/complicações , Neoplasias Gástricas/complicações , Adenocarcinoma/patologia , Idoso , Idoso de 80 Anos ou mais , Transformação Celular Neoplásica/patologia , Diagnóstico Diferencial , Gastrite Hipertrófica/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Lesões Pré-Cancerosas/patologia , Neoplasias Gástricas/patologiaAssuntos
Adrenérgicos/uso terapêutico , Raquianestesia/efeitos adversos , Efedrina/uso terapêutico , Hipotensão/prevenção & controle , Vasoconstritores/uso terapêutico , Idoso , Interpretação Estatística de Dados , Hemodinâmica , Humanos , Soluções Isotônicas/administração & dosagem , Pessoa de Meia-Idade , Perfusão , Estudos Prospectivos , Solução de RingerRESUMO
The authors report a case of mesenteric venous infarction in a pregnant woman. After having studied the clinical characteristics of this accident, they discuss the role of pregnancy in its accuracy and also the therapy that has to be adopted.