1.
Org Lett
; 16(3): 727-9, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24446807
RESUMO
Redox transformation of an α,ß-unsaturated aldehyde to a carboxylic acid derivative by means of a combination of TMSCN and DBU was investigated. In addition to the wide use of the carboxylic acid derivatives provided by this reaction, temperature-dependent control of the kinetic or thermodynamic protonation pattern was found to selectively switch the stereochemistry of the acyl group in the product.
Assuntos
Aldeídos/química , Ácidos Carboxílicos/síntese química , Cianetos/química , Compostos de Trimetilsilil/química , Ácidos Carboxílicos/química , Cinética , Estrutura Molecular , Oxirredução , Estereoisomerismo , Termodinâmica
2.
