RESUMO
The authors describe the imaging appearance of limbic encephalitis. This condition may be the presenting complaint of patients with an occult malignant lesion, as in the case reported here. The contrast-enhanced cerebral computed tomography scans of patients with limbic encephalitis may be normal, yet magnetic resonance imaging may show distinctive features. Because neurologic improvement may follow treatment of the primary tumour, early diagnosis is important.
Assuntos
Carcinoma de Células Pequenas/complicações , Encefalite/diagnóstico , Sistema Límbico , Neoplasias Pulmonares/complicações , Imageamento por Ressonância Magnética , Síndromes Paraneoplásicas/diagnóstico , Carcinoma de Células Pequenas/diagnóstico por imagem , Encefalite/etiologia , Humanos , Neoplasias Pulmonares/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Síndromes Paraneoplásicas/etiologia , Tomografia Computadorizada por Raios XRESUMO
We studied the effect of heat treatment and subsequent rehydration of heated monosodium urate monohydrate (MSUM) crystals on the physicochemical characteristics and ability of the crystals to cause hemolysis of erythrocytes (measure of membranolytic potential). MSUM crystals dehydrated slowly on heating at 200 degrees from 1-5 h and rehydration to 100% monohydrate was complete within 30 min. Heating at 250 degrees for 2 h caused rapid dehydration to anhydrous MSU and rehydration was incomplete up to 17 h. Zeta potential and percent hemolysis of MSUM crystals decreased after heating and rehydration. This reduction in percent hemolysis may be due to the reduction in surface potential (measured as zeta potential) of the crystals.