Assuntos
Cistos Aracnóideos/diagnóstico , Hemorragia Cerebral/diagnóstico , Encefalocele/diagnóstico , Hematoma Subdural Agudo/diagnóstico , Imageamento por Ressonância Magnética , Tomografia Computadorizada por Raios X , Adolescente , Cistos Aracnóideos/cirurgia , Encéfalo/patologia , Hemorragia Cerebral/cirurgia , Ventrículos Cerebrais/patologia , Constrição Patológica , Dominância Cerebral/fisiologia , Encefalocele/cirurgia , Hematoma Subdural Agudo/cirurgia , Humanos , Masculino , Exame Neurológico , Ruptura Espontânea , TrepanaçãoRESUMO
Two patients with mast cell disease presented with unusual features. In one the absence of skin lesions made the diagnositic problem a challenging one. Certain of the laboratory findings, especially those related to the serum cholesterol concentration and platelet function tests, were particularyl interesting. Chemotherapy induced partial remission. The second patient had a long, relatively benign course complicated by two episodes of herpes zoster, the last being associated with the Landry-Guillain-Barre syndrome. In both patients the skeletal abnormalities were radiologically similar. When these are present they should be considereed sufficiently characteristic to indicate strongly a diagnosis of mastocytosis.
Assuntos
Urticaria Pigmentosa/diagnóstico , Idoso , Animais , Osso e Ossos/diagnóstico por imagem , Humanos , Mastócitos/patologia , Osteoblastos , Osteólise/diagnóstico por imagem , Prednisona/uso terapêutico , Coelhos , Radiografia , Costelas/diagnóstico por imagem , Tiotepa/uso terapêutico , Urticaria Pigmentosa/diagnóstico por imagem , Urticaria Pigmentosa/patologia , Vincristina/uso terapêuticoRESUMO
A 68-year-old woman suffering from a longstanding urticaria pigmentosa with mast cell infiltrations in bones had two attacks of herpes zoster. The second herpes zoster attack was followed by a severe polyradiculoneuritis (Guillain-Barré syndrome). The sequence of events suggests an immunological deficiency.
